<SEC-DOCUMENT>0001178253-12-000001.txt : 20120203
<SEC-HEADER>0001178253-12-000001.hdr.sgml : 20120203
<ACCEPTANCE-DATETIME>20120203134723
ACCESSION NUMBER:		0001178253-12-000001
CONFORMED SUBMISSION TYPE:	D/A
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20120203
DATE AS OF CHANGE:		20120203
EFFECTIVENESS DATE:		20120203

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SCYNEXIS INC
		CENTRAL INDEX KEY:			0001178253
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		D/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-170229
		FILM NUMBER:		12569113

	BUSINESS ADDRESS:	
		STREET 1:		3501-C TRICENTER BLVD
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713
		BUSINESS PHONE:		919-544-8600

	MAIL ADDRESS:	
		STREET 1:		3501-C TRICENTER BLVD
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713
</SEC-HEADER>
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        <cik>0001178253</cik>
        <entityName>SCYNEXIS INC</entityName>
        <issuerAddress>
            <street1>3501-C TRICENTER BLVD</street1>
            <city>DURHAM</city>
            <stateOrCountry>NC</stateOrCountry>
            <stateOrCountryDescription>NORTH CAROLINA</stateOrCountryDescription>
            <zipCode>27713</zipCode>
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        <issuerPhoneNumber>919-544-8600</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>Scyrex, Inc.</previousName>
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            <relatedPersonName>
                <firstName>Yves</firstName>
                <middleName>J.</middleName>
                <lastName>Ribeill</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Scynexis, Inc.</street1>
                <street2>3501-C Tricenter Boulevard</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <stateOrCountryDescription>NORTH CAROLINA</stateOrCountryDescription>
                <zipCode>27713</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Brian</firstName>
                <middleName>J.</middleName>
                <lastName>Schwab</lastName>
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            <relatedPersonAddress>
                <street1>c/o Scynexis, Inc.</street1>
                <street2>3501-C Tricenter Boulevard</street2>
                <city>Durham</city>
                <stateOrCountry>NC</stateOrCountry>
                <stateOrCountryDescription>NORTH CAROLINA</stateOrCountryDescription>
                <zipCode>27713</zipCode>
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                <firstName>Charles</firstName>
                <middleName>F.</middleName>
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                <firstName>Pamela</firstName>
                <middleName>J.</middleName>
                <lastName>Kirby</lastName>
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                <street1>c/o Scynexis, Inc.</street1>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ed</firstName>
                <lastName>Penhoet</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Alta Partners</street1>
                <street2>One Embarcadero Center, 37th Floor</street2>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>94111</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Patrick</firstName>
                <middleName>J.</middleName>
                <lastName>Langlois</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Scynexis, Inc.</street1>
                <street2>3501-C Tricenter Boulevard</street2>
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                <stateOrCountry>NC</stateOrCountry>
                <stateOrCountryDescription>NORTH CAROLINA</stateOrCountryDescription>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ann</firstName>
                <middleName>F.</middleName>
                <lastName>Hanham</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Burrill &amp; Company</street1>
                <street2>One Embarcadero Center, Suite 2700</street2>
                <city>San Francisco</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>94111</zipCode>
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                <firstName>Laurent</firstName>
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                <street2>3501-C Tricenter Boulevard</street2>
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            <relatedPersonName>
                <firstName>Jean-Yves</firstName>
                <lastName>Nothias</lastName>
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            <relatedPersonAddress>
                <street1>c/o Scynexis, Inc.</street1>
                <street2>3501-C Tricenter Boulevard</street2>
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                <stateOrCountry>NC</stateOrCountry>
                <stateOrCountryDescription>NORTH CAROLINA</stateOrCountryDescription>
                <zipCode>27713</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Horace</firstName>
                <middleName>D.</middleName>
                <lastName>Nalle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Merial Limited</street1>
                <street2>3239 Satellite Boulevard, Building 500</street2>
                <city>Duluth</city>
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                <stateOrCountryDescription>GEORGIA</stateOrCountryDescription>
                <zipCode>30096</zipCode>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mounia</firstName>
                <lastName>Chaoui</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Ventech</street1>
                <street2>5/7 rue de Monttessuy</street2>
                <city>Paris</city>
                <stateOrCountry>I0</stateOrCountry>
                <stateOrCountryDescription>FRANCE</stateOrCountryDescription>
                <zipCode>75007</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001178253-11-000003</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2011-12-07</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>15007500</totalOfferingAmount>
            <totalAmountSold>5724671</totalAmountSold>
            <totalRemaining>9282829</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>11</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
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        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
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        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>SCYNEXIS INC</issuerName>
                <signatureName>/s/ Brian J. Schwab</signatureName>
                <nameOfSigner>Brian J. Schwab</nameOfSigner>
                <signatureTitle>Chief Licensing Officer and General Counsel</signatureTitle>
                <signatureDate>2012-02-02</signatureDate>
            </signature>
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</SEC-DOCUMENT>
