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Convertible Preferred Stock - Additional Information (Detail) (USD $) In Thousands, except Share data, unless otherwise specified | 0 Months Ended | 3 Months Ended |  | 1 Months Ended | 12 Months Ended |  |  |  |  |  | 1 Months Ended | 3 Months Ended |  |  | 1 Months Ended |  |  |  |  | 0 Months Ended |  |  | 0 Months Ended | 12 Months Ended |  |  |  |  |  | 0 Months Ended |  |  |  |  |  |
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Mar. 13, 2014 | Jan. 31, 2014 | Mar. 31, 2014 | Dec. 31, 2011 | Jan. 31, 2005 Series C Convertible Preferred Stock [Member] | Dec. 31, 2002 Series C Convertible Preferred Stock [Member] | Dec. 31, 2001 Series C Convertible Preferred Stock [Member] Investor | Mar. 31, 2014 Series C Convertible Preferred Stock [Member] | Jan. 31, 2014 Series C Convertible Preferred Stock [Member] | Dec. 31, 2013 Series C Convertible Preferred Stock [Member] | Dec. 11, 2013 Series C Convertible Preferred Stock [Member] | Dec. 31, 2012 Series C Convertible Preferred Stock [Member] | Jul. 31, 2006 Series C-1 Convertible Preferred Stock [Member] | Aug. 31, 2004 Series C-1 Convertible Preferred Stock [Member] | Mar. 31, 2014 Series C-1 Convertible Preferred Stock [Member] | Mar. 31, 2013 Series C-1 Convertible Preferred Stock [Member] | Jan. 31, 2014 Series C-1 Convertible Preferred Stock [Member] | Dec. 11, 2013 Series C-1 Convertible Preferred Stock [Member] | Mar. 31, 2008 Series C-2 Convertible Preferred Stock [Member] | Mar. 31, 2014 Series C-2 Convertible Preferred Stock [Member] | Jan. 31, 2014 Series C-2 Convertible Preferred Stock [Member] | Dec. 31, 2013 Series C-2 Convertible Preferred Stock [Member] | Dec. 11, 2013 Series C-2 Convertible Preferred Stock [Member] | Jan. 31, 2014 Series D-2 Convertible Preferred Stock [Member] | Dec. 11, 2013 Series D-2 Convertible Preferred Stock [Member] | Mar. 31, 2014 Series D-2 Convertible Preferred Stock [Member] | Dec. 31, 2013 Series D-2 Convertible Preferred Stock [Member] | Dec. 31, 2000 Series B Convertible Preferred Stock [Member] | Dec. 31, 2000 Series B Convertible Preferred Stock [Member] | Mar. 31, 2014 Series B Convertible Preferred Stock [Member] | Jan. 31, 2014 Series B Convertible Preferred Stock [Member] | Dec. 31, 2013 Series B Convertible Preferred Stock [Member] | Dec. 11, 2013 Series B Convertible Preferred Stock [Member] | Dec. 31, 2012 Series B Convertible Preferred Stock [Member] | Dec. 11, 2013 Series D-1 Convertible Preferred Stock [Member] | Mar. 31, 2014 Series D-1 Convertible Preferred Stock [Member] | Dec. 31, 2013 Series D-1 Convertible Preferred Stock [Member] | Dec. 31, 2000 Convertible Preferred Stock [Member] | Mar. 31, 2014 Series A Convertible Preferred Stock [Member] | Dec. 31, 2013 Series A Convertible Preferred Stock [Member] | Dec. 31, 2000 Series A Convertible Preferred Stock [Member]
Temporary Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, par value |  |  |  |  |  |  |  | $ 0.001 |  | $ 0.001 |  |  |  |  |  |  |  |  |  | $ 0.001 |  | $ 0.001 |  |  |  | $ 0.001 | $ 0.001 |  |  | $ 0.001 |  | $ 0.001 |  |  |  | $ 0.001 | $ 0.001 | $ 0.001 | $ 0.001 | $ 0.001 |
Preferred stock, shares issued |  |  |  |  |  | 2,867,154 |  | 2,770,633 |  | 2,770,633 |  |  |  | 984,615 |  |  |  |  | 2,347,826 | 2,347,826 |  | 2,347,826 |  | 388,641 | 1,785,712 | 6,131,338 | 5,742,697 | 600,999 | 600,999 | 467,814 |  | 467,814 |  |  |  | 6,054,255 | 6,054,255 |  | 31,407 | 31,407 | 31,407
Issue Price |  |  |  |  |  |  |  | $ 10.15 |  |  |  |  |  |  | $ 3.25 |  |  |  |  | $ 5.75 |  |  |  | $ 1.40 | $ 1.40 | $ 1.40 |  | $ 9.01 | $ 9.01 | $ 9.01 |  |  |  |  |  | $ 1.40 |  |  | $ 7.96 |  | $ 7.96
Consideration in the form of equipment, intellectual property, and conversion of existing debt |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 2,200 | $ 2,200 |  |  |  |  |  |  |  |  |  |  |  |
Consideration in cash |  | 544 | 544 |  |  | 24,000 |  |  |  |  |  |  |  | 3,200 |  |  |  |  | 13,500 |  |  |  |  |  | 2,500 |  |  |  | 3,215 |  |  |  |  |  |  |  |  |  |  |  |
Issuance costs |  |  |  |  |  | 86 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 95 |  |  | 43 |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, additional shares issued |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 110,988 | 110,988 |  |  |  |  |  |  |  |  |  |  |  |
Conversion into common stock |  |  |  |  |  |  |  |  |  |  |  | 197,045 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 244,173 |  |  |  |  |  |  |
Number of warrants issued to purchase common stock |  | 19,048 |  | 26,000 |  |  | 100,524 |  |  |  |  |  | 196,923 |  |  |  |  |  |  |  |  |  |  |  | 87,532 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants |  | 0.20 |  | 0.20 |  |  | 0.01 |  |  |  |  |  | 3.25 |  |  |  |  |  |  |  |  |  |  |  | 0.20 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of investors |  |  |  |  |  |  | 2 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration in mode of convertible notes and accrued interest |  |  |  |  |  | 4,513 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Interest on convertible notes |  |  |  |  |  | 4.50% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares issued upon exercise of warrants |  |  |  |  | 23,911 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair value of warrants, debt discount |  |  |  |  |  |  |  |  |  |  |  |  | 459 |  |  |  |  |  |  |  |  |  |  | 906 | 4,214 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Adjustment to fair value |  |  | (3,145) |  |  |  |  |  |  |  |  |  |  |  | 37 | 0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrant expiration date |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Jul. 14, 2016 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion price of preferred stock |  |  |  |  |  |  |  |  | $ 36.2386 |  | $ 51.7700 |  |  |  |  |  | $ 46.1101 | $ 66.3000 |  |  | $ 78.9623 |  | $ 117.3000 |  | $ 28.56 |  |  |  |  |  | $ 32.2912 |  | $ 45.9500 |  |  | $ 1.4000 |  |  |  |  |
Conversion price, reduced due to anti-dilution provisions |  |  |  |  |  |  |  |  | $ 35.8917 |  | $ 36.2386 |  |  |  |  |  | $ 45.6062 | $ 46.1101 |  |  | $ 77.9382 |  | $ 78.9623 |  |  |  |  |  |  |  | $ 32.0076 |  | $ 32.2912 |  |  |  |  |  |  |  |
Excess of fair value of warrants over proceeds |  |  | 362 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 362 | 1,714 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair value of common stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 47.74 | $ 48.35 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Intrinsic value |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4,232 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Effective conversion price per share |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares converted to preferred stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,956,985 |  |  |  |  |  |  |  |  |  | 6,054,255 |  |  |  |  |  |
Public offering gross proceeds threshold required to trigger provisions for automatic conversion of preferred stock | $ 20,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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- Definition Per share amount of par value or stated value of stock classified as temporary equity. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 28 -Article 5 + Details
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