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Convertible Preferred Stock - Additional Information (Detail) (USD $)
In Thousands, except Share data, unless otherwise specified
 0 Months Ended 3 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 3 Months Ended 1 Months Ended 0 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended
Mar. 13, 2014
Jan. 31, 2014
Mar. 31, 2014
Dec. 31, 2011
Jan. 31, 2005
Series C Convertible Preferred Stock [Member]
Dec. 31, 2002
Series C Convertible Preferred Stock [Member]
Dec. 31, 2001
Series C Convertible Preferred Stock [Member]
Investor
Mar. 31, 2014
Series C Convertible Preferred Stock [Member]
Jan. 31, 2014
Series C Convertible Preferred Stock [Member]
Dec. 31, 2013
Series C Convertible Preferred Stock [Member]
Dec. 11, 2013
Series C Convertible Preferred Stock [Member]
Dec. 31, 2012
Series C Convertible Preferred Stock [Member]
Jul. 31, 2006
Series C-1 Convertible Preferred Stock [Member]
Aug. 31, 2004
Series C-1 Convertible Preferred Stock [Member]
Mar. 31, 2014
Series C-1 Convertible Preferred Stock [Member]
Mar. 31, 2013
Series C-1 Convertible Preferred Stock [Member]
Jan. 31, 2014
Series C-1 Convertible Preferred Stock [Member]
Dec. 11, 2013
Series C-1 Convertible Preferred Stock [Member]
Mar. 31, 2008
Series C-2 Convertible Preferred Stock [Member]
Mar. 31, 2014
Series C-2 Convertible Preferred Stock [Member]
Jan. 31, 2014
Series C-2 Convertible Preferred Stock [Member]
Dec. 31, 2013
Series C-2 Convertible Preferred Stock [Member]
Dec. 11, 2013
Series C-2 Convertible Preferred Stock [Member]
Jan. 31, 2014
Series D-2 Convertible Preferred Stock [Member]
Dec. 11, 2013
Series D-2 Convertible Preferred Stock [Member]
Mar. 31, 2014
Series D-2 Convertible Preferred Stock [Member]
Dec. 31, 2013
Series D-2 Convertible Preferred Stock [Member]
Dec. 31, 2000
Series B Convertible Preferred Stock [Member]
Dec. 31, 2000
Series B Convertible Preferred Stock [Member]
Mar. 31, 2014
Series B Convertible Preferred Stock [Member]
Jan. 31, 2014
Series B Convertible Preferred Stock [Member]
Dec. 31, 2013
Series B Convertible Preferred Stock [Member]
Dec. 11, 2013
Series B Convertible Preferred Stock [Member]
Dec. 31, 2012
Series B Convertible Preferred Stock [Member]
Dec. 11, 2013
Series D-1 Convertible Preferred Stock [Member]
Mar. 31, 2014
Series D-1 Convertible Preferred Stock [Member]
Dec. 31, 2013
Series D-1 Convertible Preferred Stock [Member]
Dec. 31, 2000
Convertible Preferred Stock [Member]
Mar. 31, 2014
Series A Convertible Preferred Stock [Member]
Dec. 31, 2013
Series A Convertible Preferred Stock [Member]
Dec. 31, 2000
Series A Convertible Preferred Stock [Member]
Temporary Equity [Line Items]                                                                                  
Preferred stock, par value               $ 0.001   $ 0.001                   $ 0.001   $ 0.001       $ 0.001 $ 0.001     $ 0.001   $ 0.001       $ 0.001 $ 0.001 $ 0.001 $ 0.001 $ 0.001  
Preferred stock, shares issued           2,867,154   2,770,633   2,770,633       984,615         2,347,826 2,347,826   2,347,826   388,641 1,785,712 6,131,338 5,742,697 600,999 600,999 467,814   467,814       6,054,255 6,054,255   31,407 31,407 31,407
Issue Price                $ 10.15             $ 3.25         $ 5.75       $ 1.40 $ 1.40 $ 1.40   $ 9.01 $ 9.01 $ 9.01           $ 1.40     $ 7.96   $ 7.96
Consideration in the form of equipment, intellectual property, and conversion of existing debt                                                       $ 2,200 $ 2,200                        
Consideration in cash   544 544     24,000               3,200         13,500           2,500       3,215                        
Issuance costs           86                                     95     43                          
Preferred stock, additional shares issued                                                       110,988 110,988                        
Conversion into common stock                       197,045                                           244,173              
Number of warrants issued to purchase common stock   19,048   26,000     100,524           196,923                       87,532                                
Exercise price of warrants   0.20   0.20     0.01           3.25                       0.20                                
Number of investors             2                                                                    
Consideration in mode of convertible notes and accrued interest           4,513                                                                      
Interest on convertible notes           4.50%                                                                      
Number of shares issued upon exercise of warrants         23,911                                                                        
Fair value of warrants, debt discount                         459                     906 4,214                                
Adjustment to fair value     (3,145)                       37 0                                                  
Warrant expiration date                             Jul. 14, 2016                                                    
Conversion price of preferred stock                 $ 36.2386   $ 51.7700           $ 46.1101 $ 66.3000     $ 78.9623   $ 117.3000   $ 28.56           $ 32.2912   $ 45.9500     $ 1.4000          
Conversion price, reduced due to anti-dilution provisions                 $ 35.8917   $ 36.2386           $ 45.6062 $ 46.1101     $ 77.9382   $ 78.9623               $ 32.0076   $ 32.2912                
Excess of fair value of warrants over proceeds     362                                         362 1,714                                
Fair value of common stock                                               $ 47.74 $ 48.35                                
Intrinsic value                                                 4,232                                
Effective conversion price per share                                                 $ 0                                
Shares converted to preferred stock                                                 3,956,985                   6,054,255            
Public offering gross proceeds threshold required to trigger provisions for automatic conversion of preferred stock $ 20,000