<SEC-DOCUMENT>0001628280-16-016942.txt : 20160606
<SEC-HEADER>0001628280-16-016942.hdr.sgml : 20160606
<ACCEPTANCE-DATETIME>20160606132114
ACCESSION NUMBER:		0001628280-16-016942
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160602
FILED AS OF DATE:		20160606
DATE AS OF CHANGE:		20160606

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SCYNEXIS INC
		CENTRAL INDEX KEY:			0001178253
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				562181648
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		101 HUDSON STREET
		STREET 2:		SUITE 3610
		CITY:			JERSEY CITY
		STATE:			NJ
		ZIP:			07302-6548
		BUSINESS PHONE:		201-884-5485

	MAIL ADDRESS:	
		STREET 1:		101 HUDSON STREET
		STREET 2:		SUITE 3610
		CITY:			JERSEY CITY
		STATE:			NJ
		ZIP:			07302-6548

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Macdonald Guy
		CENTRAL INDEX KEY:			0001296998

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36365
		FILM NUMBER:		161698108

	MAIL ADDRESS:	
		STREET 1:		C/O IDENIX PHARMACEUTICALS, INC.
		STREET 2:		60 HAMPSHIRE STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wf-form4_146523366127923.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2016-06-02</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001178253</issuerCik>
        <issuerName>SCYNEXIS INC</issuerName>
        <issuerTradingSymbol>SCYX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001296998</rptOwnerCik>
            <rptOwnerName>Macdonald Guy</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SCYNEXIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>101 HUDSON STREET, SUITE 3610</rptOwnerStreet2>
            <rptOwnerCity>JERSEY CITY</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07302-6548</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.98</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-06-02</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>8800</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.98</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2026-06-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>8800.0</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8800</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">One-hundred percent (100%) of the shares subject to the option vest on the earlier of (i) the first anniversary of the date of grant, and (ii) the date of the next Annual Meeting of Stockholders of the Issuer.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Robert F. Joyce Jr., by Power of Attorney</signatureName>
        <signatureDate>2016-06-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
