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Income Taxes Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2016
Income Tax Disclosure [Abstract] |
Schedule of Effective Income Tax Rate Reconciliation | Reconciliations of the differences between the benefit for income taxes and income taxes at the statutory U.S. federal income tax rate is as follows:
| Years Ended December 31,
| 2016 |  | 2015 |  | 2014
| Amount |  | Percent of Pretax Income |  | Amount |  | Percent of Pretax Income |  | Amount |  | Percent of Pretax Income
Income taxes from continuing operations at statutory rate | $ | (10,196 | ) |  | 34.0 | % |  | $ | (9,635 | ) |  | 34.0 | % |  | $ | (2,301 | ) |  | 34.0 | %
State income taxes | (1,287 | ) |  | 4.3 | % |  | (196 | ) |  | 0.7 | % |  | (471 | ) |  | 7.0 | %
Stock warrant derivative liability | — |  |  | — |  |  | — |  |  | — |  |  | (3,427 | ) |  | 50.6 | %
Stock-based compensation | 215 |  |  | (0.8 | )% |  | 15 |  |  | (0.1 | )% |  | 268 |  |  | (4.0 | )%
R&D tax credits | (955 | ) |  | 3.2 | % |  | (1,152 | ) |  | 4.1 | % |  | (320 | ) |  | 4.7 | %
Loss on sale of discontinued operations, net of reduction in related valuation allowances | — |  |  | — |  |  | (1,458 | ) |  | 5.1 | % |  | — |  |  | — |
Warrants issuance | 730 |  |  | (2.4 | )% |  | — |  |  | — |  |  | — |  |  | — |
Other | 719 |  |  | (2.4 | )% |  | (127 | ) |  | 0.5 | % |  | (190 | ) |  | 2.8 | %
Increase in valuation allowance | 10,774 |  |  | (35.9 | )% |  | 12,553 |  |  | (44.3 | )% |  | 5,275 |  |  | (77.9 | )%
Total income tax benefit | $ | — |  |  | — | % |  | $ | — |  |  | — | % |  | $ | (1,166 | ) |  | 17.2 | %
Schedule of Deferred Tax Assets and Liabilities | The components of deferred tax assets and liabilities as of December 31, 2016 and 2015 are as follows:
| December 31,
| 2016 |  | 2015
Current deferred tax assets: |  |  |
Accrued expenses | $ | 215 |  |  | $ | 783 |
Stock-based compensation | 1,664 |  |  | 1,507 |
Other | 39 |  |  | 19 |
| 1,918 |  |  | 2,309 |
Noncurrent deferred tax assets (liabilities); |  |  |
Net operating loss carryforwards | 53,173 |  |  | 42,358 |
Research and development credits | 4,185 |  |  | 3,836 |
| 57,358 |  |  | 46,194 |
Total deferred tax assets | 59,276 |  |  | 48,503 |
Valuation allowances | (59,276 | ) |  | (48,503 | )
Net deferred tax assets | $ | — |  |  | $ | — |
Schedule of Unrecognized Tax Benefits Roll Forward | The following is a tabular reconciliation of the total amounts of unrecognized tax benefits as of December 31, 2016 and 2015:
| December 31,
| 2016 |  | 2015
Unrecognized tax benefit—January 1 | $ | 623 |  |  | $ | 623 |
Additions for tax positions of current period | — |  |  | — |
Additions for tax positions of prior periods | — |  |  | — |
Other | — |  |  | — |
Unrecognized tax benefit—December 31 | $ | 623 |  |  | $ | 623 |

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