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Stockholders' Equity - Schedule of Reserved Shares of Common Stock for Future Issuance (Detail) - shares | Dec. 31, 2016 | Sep. 30, 2016 | Dec. 31, 2015 | Dec. 31, 2014
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Class of Stock [Line Items] |  |  |  |
Outstanding stock options (in shares) | 1,819,444 |  | 1,379,727 | 615,322
Outstanding Series C-1 convertible preferred stock warrants (in shares) | 14,033 |  | 14,033 |
Total common shares reserved for future issuance (in shares) | 7,080,921 |  | 2,161,458 |
2014 Equity Incentive Plan |  |  |  |
Class of Stock [Line Items] |  |  |  |
For possible future issuance under stock option plan (in shares) | 668,921 |  | 552,415 |
2014 Employee Stock Purchase Plan |  |  |  |
Class of Stock [Line Items] |  |  |  |
For possible future issuance under stock option plan (in shares) | 72,338 |  | 50,283 |
2015 Inducement Plan |  |  |  |
Class of Stock [Line Items] |  |  |  |
For possible future issuance under stock option plan (in shares) | 165,000 |  | 165,000 |
June 2016 Public Offering |  |  |  |
Class of Stock [Line Items] |  |  |  |
Warrants to purchase common stock (shares) | 4,218,750 |  | 0 |
Warrants Associated with Loan Agreement |  |  |  |
Class of Stock [Line Items] |  |  |  |
Outstanding Series C-1 convertible preferred stock warrants (in shares) |  | 122,435 |  |
Warrants to purchase common stock (shares) | 122,435 |  | 0 |

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- Definition Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)(2)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 + Details
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