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Stockholders' Equity - Additional Information (Detail) - USD ($) |  |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Sep. 30, 2016 | Jun. 21, 2016 | Jul. 31, 2006 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014 | May 07, 2014
Equity [Abstract] |  |  |  |  |  |  |
Common stock, par value (in dollars per share) |  |  |  | $ 0.001 | $ 0.001 |  |
Common stock, shares authorized (in shares) |  |  |  | 125,000,000 | 125,000,000 |  |
Common stock, shares outstanding (in shares) |  |  |  | 24,609,411 | 13,905,599 | 8,512,103 |
Common stock, shares issued (in shares) |  |  |  | 24,609,411 | 13,905,599 |  |
Preferred shares authorized (in shares) |  |  |  | 5,000,000 | 5,000,000 |  | 5,000,000
Preferred shares par value (in dollars per share) |  |  |  | $ 0.001 | $ 0.001 |  | $ 0.001
Preferred shares issued (in shares) |  |  |  | 0 | 0 |  |
Preferred shares outstanding (in shares) |  |  |  | 0 | 0 |  |
Schedule of Capitalization, Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  |  | 14,033 | 14,033 |  |
Change in fair value of derivative liability |  |  |  | $ 1,906,000 | $ 0 | $ 0 |
Warrant liability |  |  |  | 6,601,000 | 0 |  |
Warrants Associated with Loan Agreement |  |  |  |  |  |  |
Schedule of Capitalization, Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) | 122,435 |  |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ 3.6754 |  |  |  |  |  |
Warrants issued, expiration period (in years) | 5 years |  |  |  |  |  |
June 2016 Public Offering |  |  |  |  |  |  |
Schedule of Capitalization, Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 4,218,750 |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 3.00 |  |  |  |  |
Number of shares received per warrant (in shares) |  | 0.45 |  |  |  |  |
Warrants issued, expiration period (in years) |  | 5 years |  |  |  |  |
Series C-1 Convertible Preferred Stock |  |  |  |  |  |  |
Schedule of Capitalization, Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 196,923 |  |  |  |
Exercise price of warrants (in dollars per share) |  |  | $ 3.25 |  |  |  |
Fair value of warrant on issuance date |  |  | $ 459,000 |  |  |  |
Derivative liability |  |  |  | $ 0 | $ 0 |  |
Common Stock |  |  |  |  |  |  |
Schedule of Capitalization, Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 14,033 |  |  |  |
Exercise price of warrants (in dollars per share) |  |  | $ 45.61 |  |  |  |

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