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Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | ---
Income Tax Disclosure [Abstract] |  |
Accrued expenses | $ 215 | $ 783
Stock-based compensation | 1,664 | 1,507
Other | 39 | 19
Current deferred tax assets | 1,918 | 2,309
Net operating loss carryforwards | 53,173 | 42,358
Research and development credits | 4,185 | 3,836
Noncurrent deferred tax assets (liabilities) | 57,358 | 46,194
Total deferred tax assets | 59,276 | 48,503
Valuation allowances | (59,276) | (48,503)
Net deferred tax assets | $ 0 | $ 0

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