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Summary of Significant Accounting Policies - Concentration Risk (Details) - Customer Concentration Risk - Sales
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Waterstone Pharmaceuticals      
Concentration Risk [Line Items]      
Percentage of total revenue 0.00% 0.00% 80.00%
R-Pharm, CJSC      
Concentration Risk [Line Items]      
Percentage of total revenue 100.00% 100.00% 20.00%