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Stockholders' Equity - Schedule of Reserved Shares of Common Stock for Future Issuance (Detail) - shares
Dec. 31, 2016
Sep. 30, 2016
Dec. 31, 2015
Dec. 31, 2014
Class of Stock [Line Items]        
Outstanding stock options (in shares) 1,819,444   1,379,727 615,322
Outstanding Series C-1 convertible preferred stock warrants (in shares) 14,033   14,033  
Total common shares reserved for future issuance (in shares) 7,080,921   2,161,458  
2014 Equity Incentive Plan        
Class of Stock [Line Items]        
For possible future issuance under stock option plan (in shares) 668,921   552,415  
2014 Employee Stock Purchase Plan        
Class of Stock [Line Items]        
For possible future issuance under stock option plan (in shares) 72,338   50,283  
2015 Inducement Plan        
Class of Stock [Line Items]        
For possible future issuance under stock option plan (in shares) 165,000   165,000  
June 2016 Public Offering        
Class of Stock [Line Items]        
Warrants to purchase common stock (shares) 4,218,750   0  
Warrants Associated with Loan Agreement        
Class of Stock [Line Items]        
Outstanding Series C-1 convertible preferred stock warrants (in shares)   122,435    
Warrants to purchase common stock (shares) 122,435   0