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Stock-based Compensation - Stock-based Compensation Plan Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Number of Shares      
Number of Outstanding Stock Options, beginning balance (in shares) 1,379,727 615,322  
Number of Shares Granted (in shares) 497,978 880,116  
Number of Shares Exercised (in shares) 0 0  
Number of Shares Canceled (in shares) (58,261) (115,711)  
Number of Outstanding Stock Options, ending balance (in shares) 1,819,444 1,379,727 615,322
Number of Shares Exercisable (in shares) 1,022,515 635,548  
Number of Options Vested or Expected to Vest (in shares) 1,779,597 1,342,518  
Weighted- Average Exercise Price      
Beginning balance (in dollars per share) $ 8.71 $ 9.55  
Granted in Period, per share (in dollars per share) 4.23 8.17  
Exercised, per share (in dollars per share) 0.00 0.00  
Canceled, per share (in dollars per share) 7.47 9.05  
Ending balance (in dollars per share) 7.52 8.71 $ 9.55
Weighted Average Exercise Price of Options Exercisable, per share (in dollars per share) 8.59 9.41  
Weighted Average Exercise Price of Options Vested or Expected to Vest, per share (in dollars per share) $ 7.55 $ 8.73  
Weighted- Average Remaining Contractual Life (in years) 6 years 11 months 23 days 7 years 2 months 5 days 9 years 5 months 23 days
Weighted- Average Remaining Contractual Life, Exercisable (in years) 5 years 6 months 4 days 4 years 6 months 22 days  
Weighted- Average Remaining Contractual Life, Vested or Expected to Vest (in years) 6 years 11 months 9 days 7 years 1 month 10 days  
Aggregate Intrinsic Value $ 32,000 $ 0 $ 265,000
Aggregate Intrinsic Value of Options Exercisable 15,000 0  
Aggregate Intrinsic Value of Options Vested or Expected to Vest 31,000 0  
Total fair value of shares vested during the year 1,534,000 595,000 458,000
Stock option compensation not yet recognized $ 2,739,000    
Share based compensation cost recognition period 2 years 8 months 12 days    
Intrinsic value of options exercised $ 0 $ 0 $ 11,000