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Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:      
Net loss $ (29,989,000) $ (32,623,000) $ (4,234,000)
Adjustments to reconcile net loss to net cash used in operating activities:      
Non-cash component of impairment loss on classification of assets as held for sale 0 586,000 0
Gain on insurance recovery 0 0 (165,000)
Loss on disposal of Services Business 0 73,000 0
Loss on extinguishment of debt 0 0 1,389,000
Write off of deferred offering costs 111,000 0 0
Depreciation 26,000 447,000 1,238,000
Stock-based compensation expense 1,210,000 3,023,000 1,201,000
Amortization of investment premium 315,000 0 0
Amortization of deferred financing costs and debt discount 100,000 0 755,000
Change in fair value of derivative liability 1,906,000 0 0
Derivative fair value adjustment 0 0 (10,080,000)
Changes in deferred rent 1,000 (108,000) (187,000)
Changes in operating assets and liabilities:      
Accounts receivable and unbilled services 0 31,000 (439,000)
Prepaid expenses, other assets, and deferred costs 172,000 (633,000) (490,000)
Accounts payable and accrued expenses (309,000) 1,066,000 1,575,000
Accrued severance and retention cost obligations (2,639,000) 2,639,000 0
Deferred revenue (257,000) 954,000 (35,000)
Net cash used in operating activities (29,353,000) (24,545,000) (9,472,000)
Cash flows from investing activities:      
Maturities of investments 12,300,000 0 0
Proceeds from insurance recovery 0 0 216,000
Proceeds from sale of Services Business 500,000 2,549,000 0
Maturity of a security 300,000 0 0
Purchase of a security 0 (300,000) 0
Payment of security deposit 0 (74,000) 0
Purchases of property and equipment (27,000) (589,000) (704,000)
Purchase of investments (35,545,000) 0 0
Net cash (used in) provided by investing activities (22,472,000) 1,586,000 (488,000)
Cash flows from financing activities:      
Proceeds from common stock issued 28,077,000 41,400,000 62,000,000
Proceeds from sale of preferred stock 0 0 544,000
Repayment of debt 0 0 (15,000,000)
Proceeds from Loan Agreement 15,000,000 0 0
Payments of Loan Agreement issuance costs (604,000) 0 0
Payments of offering costs and underwriting discounts and commissions (1,996,000) (3,805,000) (6,875,000)
Proceeds from employee stock purchase plan issuances 19,000 106,000 68,000
Proceeds from exercise of stock warrants 0 0 55,000
Proceeds from exercise of stock options 0 0 9,000
Net cash provided by financing activities 40,496,000 37,701,000 40,801,000
Net (decrease) increase in cash and cash equivalents (11,329,000) 14,742,000 30,841,000
Cash and cash equivalents, beginning of period 46,985,000 32,243,000 1,402,000
Cash and cash equivalents, end of period 35,656,000 46,985,000 32,243,000
Supplemental cash flow information:      
Cash paid for interest 351,000 0 49,000
Cash received for interest 478,000 0 0
Noncash financing and investing activities:      
Beneficial conversion feature on sale of Series D-2 preferred stock 0 0 909,000
Beneficial conversion feature for antidilution adjustment 0 0 214,000
Adjustment of preferred stock to redemption value 0 0 510,000
Issuance of warrants allocated to debt discount 0 0 906,000
Equipment purchases in accounts payable and accrued expenses 0 0 34,000
Impairment of fixed asset 0 0 51,000
Deferred offering costs reclassified to additional paid-in capital 79,000 3,388,000 4,126,000
Warrant derivative liability reclassified to additional paid-in capital 0 0 2,701,000
Conversion of convertible preferred stock to common stock 0 0 88,790,000
Proceeds from sale of Services Business held in escrow $ 0 $ 500,000 $ 0