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Stockholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  |  |  | 1 Months Ended | 12 Months Ended |  |  |
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Dec. 12, 2019 | Sep. 14, 2018 | Mar. 08, 2018 | Sep. 30, 2016 | Jun. 21, 2016 | Apr. 30, 2019 | Dec. 31, 2019 | Dec. 31, 2018 | Jun. 18, 2019 | Jun. 17, 2019 | May 07, 2014
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) |  |  |  |  |  |  | $ 0.001 | $ 0.001 |  |  |
Common stock, shares authorized (in shares) |  |  |  |  |  |  | 250,000,000 | 125,000,000 | 250,000,000 | 125,000,000 |
Common stock, shares issued (in shares) |  |  |  |  |  |  | 97,413,721 | 47,971,989 |  |  |
Common stock, shares outstanding (in shares) |  |  |  |  |  |  | 97,413,721 | 47,971,989 |  |  |
Preferred stock, shares authorized (in shares) |  |  |  |  |  |  | 5,000,000 | 5,000,000 |  |  | 5,000,000
Preferred stock, par value (in dollars per share) |  |  |  |  |  |  | $ 0.001 | $ 0.001 |  |  | $ 0.001
Preferred stock, shares issued (in shares) |  |  |  |  |  |  | 0 | 0 |  |  |
Preferred stock, shares outstanding (in shares) |  |  |  |  |  |  | 0 | 0 |  |  |
Derivative liability fair value adjustment |  |  |  |  |  |  | $ 1,567 | $ 0 |  |  |
Common stock issued, net of expenses (in shares) |  |  | 17,751,500 |  | 9,375,000 |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 13,198,075 |  |  |  |  |  |  |  |  |
Warrants, expiration date |  | Mar. 14, 2019 |  |  |  |  |  |  |  |  |
Warrant liabilities fair value adjustment |  |  |  |  |  |  | 4,497 | $ (11,866) |  |  |
Warrant liabilities |  |  |  |  |  |  | 18,400 |  |  |  |
Warrants to purchase common stock associated with Loan Agreement |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  |  | 122,435 |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  |  |  | $ 3.6754 |  |  |  |  |  |  |
Warrant expiration period |  |  |  | 5 years |  |  |  |  |  |  |
June 2016 Public Offering |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 4,218,750 |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 3.00 |  |  | $ 3.00 |  |  |  |  |  |
Number of shares received per warrant (in shares) |  |  |  |  | 0.45 |  |  |  |  |  |
Warrant expiration period |  |  |  |  | 5 years |  |  |  |  |  |
March 2018 Public Offering |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock issued, net of expenses (in shares) |  |  | 17,751,500 |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 21,301,800 |  |  |  |  |  |  |  |
December 2019 Public Offering |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock issued, net of expenses (in shares) | 38,888,889 |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) | 38,888,889 |  |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ 1.10 |  |  |  |  |  |  |  |  |  |
Warrants, expiration date | Jun. 12, 2023 |  |  |  |  |  |  |  |  |  |
Warrant liabilities fair value adjustment |  |  |  |  |  |  | 1,000 |  |  |  |
Underwriters | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Option to purchase shares of common stock | 5,833,333 |  |  |  |  |  |  |  |  |  |
Warrant liability | June 2016 Public Offering | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  |  |  | 4,218,750 |  |  |  |  |  |
Warrant liability | March 2018 Public Offering | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 21,301,800 |  |  |  |  |  |  |  |
Warrant liability | December 2019 Public Offering | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) | 38,888,889 |  |  |  |  |  |  |  |  |  |
Warrant liability | Underwriters |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) | 5,833,333 |  |  |  |  |  |  |  |  |  |
Number of warrants exercised | 5,833,333 |  |  |  |  |  |  |  |  |  |
Series 1 Warrant |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  |  |  |  |  |  | 115,550 |  |  |
Proceeds from Warrant Exercises |  |  |  |  |  |  |  | $ 200 |  |  |
Warrants, expiration date |  |  | Mar. 14, 2019 |  |  |  |  |  |  |  |
Series 1 Warrant | March 2018 Public Offering |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 13,198,075 |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 1.85 | $ 1.85 |  |  |  |  |  |  |  |
Number of shares received per warrant (in shares) |  |  | 0.75 |  |  |  |  |  |  |  |
Warrant term |  |  | 371 days |  |  |  |  |  |  |  |
Series 1 Warrant | March 2018 Public Offering | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 13,313,625 |  |  |  |  |  |  |  |
Series 2 Warrant | March 2018 Public Offering |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 7,988,175 |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 2.00 | $ 2.00 |  |  |  |  |  |  |  |
Number of shares received per warrant (in shares) |  |  | 0.45 |  |  |  |  |  |  |  |
Warrant term |  |  | 5 years |  |  |  |  |  |  |  |
Series 2 Warrant | March 2018 Public Offering | Maximum |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 7,988,175 |  |  |  |  |  |  |  |
Senior Convertible Note Purchase Agreement |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Conversion of convertible note, amount |  |  |  |  |  | $ 2,000 |  |  |  |  |
Conversion of convertible note exchanged for shares |  |  |  |  |  | 1,626,000 |  |  |  |  |
Senior Convertible Note Purchase Agreement | Other (Income) Expense |  |  |  |  |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |  |  |  |  |
Derivative liability fair value adjustment |  |  |  |  |  |  | $ 1,600 |  |  |  |

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