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Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Aug. 31, 2013 USD ($) | Dec. 31, 2019 USD ($) Segment | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($)
Subsidiary, Sale of Stock [Line Items] |  |  |  |
Cash, cash equivalents, and restricted cash |  | $ 42,193 | $ 11,767 | $ 11,469
Upfront payment received | $ 1,500 |  |  |
Deferred revenue estimated performance period | 70 months |  |  |
Revenue recognized from upfront payments |  | $ 121 | 257 |
Operating segments (number) | Segment |  | 1 |  |
License and Service |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |
Revenue recognized from upfront payments |  | $ 100 | $ 300 |
6.0% Convertible Senior Notes due 2025 |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |
Interest rate |  | 6.00% |  |
Collaboration Revenue | R-Pharm, CJSC | Customer Concentration Risk |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |
Percentage of total revenue |  | 100.00% | 100.00% |

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