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Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands | Total | Common Stock | Additional Paid-in Capital | Accumulated Deficit
--- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2017 | $ 21,410 | $ 29 | $ 226,631 | $ (205,250)
Beginning balance (in shares) at Dec. 31, 2017 |  | 28,971,651 |  |
Net loss | (12,468) |  |  | (12,468)
Stock-based compensation expense | 1,816 |  | 1,816 |
Common stock issued through employee stock purchase plan | 39 |  | 39 |
Common stock issued through employee stock purchase plan (in shares) |  | 31,361 |  |
Common stock issued, net of expenses | 20,437 | $ 19 | 20,418 |
Common stock issued, net of expenses (in shares) |  | 18,959,675 |  |
Common stock issued for vested restricted stock units | (9) |  | (9) |
Common stock issued for vested restricted stock units (in shares) |  | 9,302 |  |
Ending balance at Dec. 31, 2018 | $ 31,225 | $ 48 | 248,895 | (217,718)
Ending balance (in shares) at Dec. 31, 2018 | 47,971,989 | 47,971,989 |  |
Net loss | $ (53,710) |  |  | (53,710)
Stock-based compensation expense | 1,828 |  | 1,828 |
Common stock issued through employee stock purchase plan | 37 |  | 37 |
Common stock issued through employee stock purchase plan (in shares) |  | 36,847 |  |
Common stock issued, net of expenses | 30,530 | $ 47 | 30,483 |
Common stock issued, net of expenses (in shares) |  | 47,736,920 |  |
Common stock issued for April 2019 conversion of Notes | 2,984 | $ 2 | 2,982 |
Common stock issued for April 2019 conversion of Notes (in shares) |  | 1,626,000 |  |
Common stock issued for exercise of stock options | $ 12 |  | 12 |
Common stock issued for exercise of stock options (in shares) | 22,500 | 22,500 |  |
Common stock issued for vested restricted stock units | $ (11) |  | (11) |
Common stock issued for vested restricted stock units (in shares) |  | 19,465 |  |
Ending balance at Dec. 31, 2019 | $ 12,895 | $ 97 | $ 284,226 | $ (271,428)
Ending balance (in shares) at Dec. 31, 2019 | 97,413,721 | 97,413,721 |  |

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