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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Shares (Details) - shares
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 15,111,905 7,697,433
Outstanding stock options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 1,371,606 768,354
Outstanding restricted stock units    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 96,974 85,754
Warrants to purchase common stock associated with June 2016 Public Offering | Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 421,867 421,867
March 2018 Public Offering Series 2 | Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 798,810 798,810
December 2019 Public Offering | Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 4,472,205 4,472,205
December 2020 Public Offering Series 2 | Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 6,800,000 0
Common stock associated with March 2019 Notes    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 1,138,200 1,138,200
Warrants to purchase common stock associated with Solar loan agreement | Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive securities (in shares) 12,243 12,243