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Unaudited Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities:    
Net loss $ (4,676) $ (7,002)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 27 28
Stock-based compensation expense 398 410
Accretion of investments discount 0 (31)
Amortization of debt issuance costs and discount 256 278
Change in fair value of warrant liabilities (1,296) (4,768)
Change in fair value of derivative liabilities 90 (700)
Noncash operating lease expense for right-of-use asset 49 48
Loss on extinguishment of debt 2,725 0
Changes in operating assets and liabilities:    
Prepaid expenses, other assets, deferred costs, and other 1,736 1,734
Accounts payable, accrued expenses, and other (68) (4,054)
Net cash used in operating activities (759) (14,057)
Cash flows from investing activities:    
Maturities of investments 0 6,477
Purchases of property and equipment 0 (4)
Purchase of intangible assets (200) 0
Purchases of investments 0 (14,235)
Net cash used in investing activities (200) (7,762)
Cash flows from financing activities:    
Proceeds from common stock issued 0 214
Payments of offering costs and underwriting discounts and commissions (62) (7)
Proceeds from common stock issuance under employee stock purchase plan 6 18
Repurchase of shares to satisfy tax withholdings (15) (73)
Net cash (used in) provided by financing activities (71) 152
Net decrease in cash, cash equivalents, and restricted cash (1,030) (21,667)
Cash, cash equivalents, and restricted cash at beginning of period 93,314 42,193
Cash, cash equivalents, and restricted cash at end of period 92,284 20,526
Supplemental cash flow information:    
Cash paid for interest 420 420
Cash received for interest 5 129
Noncash financing and investing activities:    
Common stock issued for settlement of senior convertible notes 7,452 0
Purchased intangible assets included in accounts payable and accrued expenses 178 0
Deferred offering and issuance costs included in accounts payable and accrued expenses $ 0 $ 40