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Summary of Significant Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2022
Accounting Policies [Abstract] |
Schedule of Diluted Net Loss Per Common Share | The Company calculates net loss per common share in accordance with ASC 260, Earnings Per Share. Basic net loss per common share for the three and nine months ended September 30, 2022 and 2021 was determined by dividing net loss applicable to common stockholders by the weighted average number of common shares outstanding during the period. Per ASC 260, Earnings Per Share, the weighted average number of common shares outstanding utilized for determining the basic net loss per common share for the three and nine months ended September 30, 2022 includes the outstanding pre-funded warrants to purchase 11,666,667 and 3,200,000 shares of common stock issued in the April 2022 Public Offering and December 2020 public offering, respectively. The outstanding pre-funded warrants to purchase 3,200,000 shares of common stock issued in the December 2020 public offering were included in the three and nine months ended September 30, 2021. Diluted net loss per common share for the three and nine months ended September 30, 2022 and 2021 was determined as follows (in thousands, except share and per share amounts):
| Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
| 2022 |  |  | 2021 |  |  | 2022 |  |  | 2021 |
Net loss | $ | (29,584 | ) |  | $ | (605 | ) |  | $ | (48,380 | ) |  | $ | (3,623 | )
Dilutive effect of warrant liability |  | — |  |  |  | — |  |  |  | — |  |  |  | (15,719 | )
Dilutive effect of convertible debt |  | — |  |  |  | (988 | ) |  |  | — |  |  |  | — |
Net loss allocated to common shares | $ | (29,584 | ) |  | $ | (1,593 | ) |  | $ | (48,380 | ) |  | $ | (19,342 | )
Weighted average common shares outstanding – basic |  | 47,503,821 |  |  |  | 26,616,628 |  |  |  | 40,965,908 |  |  |  | 26,147,658 |
Dilutive effect of warrant liability |  | — |  |  |  | — |  |  |  | — |  |  |  | 178,348 |
Dilutive effect of convertible debt |  | — |  |  |  | 1,138,200 |  |  |  | — |  |  |  | — |
Weighted average common shares outstanding – diluted |  | 47,503,821 |  |  |  | 27,754,828 |  |  |  | 40,965,908 |  |  |  | 26,326,006 |
Net loss per share – diluted | $ | (0.62 | ) |  | $ | (0.06 | ) |  | $ | (1.18 | ) |  | $ | (0.73 | )
Summary of Antidilutive Securities Excluded from Computation of Weighted Average Common Stock Outstanding | The following potentially dilutive shares of common stock have not been included in the computation of diluted net loss per share for the three and nine months ended September 30, 2022 and 2021, as the result would be anti-dilutive:
| Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
| 2022 |  |  | 2021 |  |  | 2022 |  |  | 2021 |
Outstanding stock options |  | 2,125,002 |  |  |  | 1,643,506 |  |  |  | 2,125,002 |  |  |  | 1,643,506 |
Outstanding restricted stock units |  | 990,015 |  |  |  | 149,134 |  |  |  | 990,015 |  |  |  | 149,134 |
Warrants to purchase common stock associated with March 2018 public offering – Series 2 |  | 798,810 |  |  |  | 798,810 |  |  |  | 798,810 |  |  |  | 798,810 |
Warrants to purchase common stock associated with December 2019 public offering |  | — |  |  |  | 4,472,205 |  |  |  | — |  |  |  | 4,472,205 |
Warrants to purchase common stock associated with December 2020 public offering - Series 1 |  | — |  |  |  | 6,439,866 |  |  |  | — |  |  |  | — |
Warrants to purchase common stock associated with December 2020 public offering - Series 2 |  | 6,800,000 |  |  |  | 6,800,000 |  |  |  | 6,800,000 |  |  |  | 6,800,000 |
Warrants to purchase common stock associated with April 2022 Public Offering |  | 15,000,000 |  |  |  | — |  |  |  | 15,000,000 |  |  |  | — |
Warrants to purchase common stock associated with Loan Agreement |  | 198,819 |  |  |  | 170,410 |  |  |  | 198,819 |  |  |  | 170,410 |
Common stock associated with March 2019 Notes |  | 1,138,200 |  |  |  | — |  |  |  | 1,138,200 |  |  |  | 1,138,200 |
Warrants to purchase common stock associated with Danforth |  | 50,000 |  |  |  | — |  |  |  | 50,000 |  |  |  | — |
Total |  | 27,100,846 |  |  |  | 20,473,931 |  |  |  | 27,100,846 |  |  |  | 15,172,265 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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