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Description of Business and Basis of Preparation - Additional Information (Detail) - USD ($)
Jun. 30, 2023
May 31, 2023
Mar. 31, 2023
Mar. 30, 2023
Dec. 31, 2022
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Accumulated deficit $ (333,904,000)       $ (422,288,000)
Cash and cash equivalents and short-term investments 91,900,000        
Loan Agreement Amendment          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Prepayment fee payable       $ 262,500  
Upfront fee received   $ 90,000,000.0      
Hercules Capital and Silicon Valley Bridge Bank [Member] | Loan Agreement Amendment          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Prepayment fee payable 300,000   $ 35,000,000.0    
Final payment payable under loan agreement $ 1,400,000