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Stockholders' Equity - Schedule of Reserved Shares of Common Stock for Future Issuance (Detail) - shares | Mar. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 41,917,113 | 40,613,284
Stock options |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 2,716,602 | 1,867,795
Restricted Stock Units |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 3,202,012 | 1,886,374
Warrant | December 2020 Public Offering Series 2 |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 6,800,000 | 6,800,000
Warrant | Prefunded Warrants to Purchase Common Stock Associated with December 2020 Public Offering |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 3,200,000 | 3,200,000
Warrant | Warrants to Purchase Common Stock Associated With April 2022 Public Offering |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 15,000,000 | 15,000,000
Warrant | April 2022 Public Offering |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 7,516,267 | 7,516,267
Warrant | Warrant to purchase common stock associated with Danforth |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 50,000 | 50,000
Warrant | Warrants to purchase common stock associated with Loan Agreement |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 198,811 | 198,811
March 2019 Notes |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 1,138,200 | 1,138,200
2014 Employee Stock Purchase Plan |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 1,458,171 | 1,474,045
2014 Plan |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 0 | 848,202
2015 Plan |  |
Class of Stock [Line Items] |  |
Common shares reserved for future issuance | 637,050 | 633,590

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