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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Shares (Detail) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 22,493,164 24,419,347 22,493,164 24,419,347
Outstanding stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 2,842,808 1,970,536 2,842,808 1,970,536
Outstanding restricted stock units        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 3,263,345 400,000 3,263,345 400,000
December 2020 Public Offering Series 2 | Warrant        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 0 6,800,000 0 6,800,000
April 2022 Public Offering | Warrant        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 15,000,000 15,000,000 15,000,000 15,000,000
Warrants to purchase common stock associated with Loan Agreement | Warrant        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 198,811 198,811 198,811 198,811
Common stock associated with March 2019 Notes        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 1,138,200 0 1,138,200 0
Warrants to purchase common stock associated with Danforth | Warrant        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Anti-dilutive securities (in shares) 50,000 50,000 50,000 50,000