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Stockholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Nov. 06, 2024 | Apr. 22, 2022 | Nov. 30, 2021 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | May 07, 2014
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock, par value (in dollars per share) |  |  |  | $ 0.001 | $ 0.001 |  |
Common stock, shares authorized (in shares) |  |  |  | 150,000,000 | 150,000,000 |  |
Common stock, shares issued (in shares) |  |  |  | 37,973,991 | 37,207,799 |  |
Common stock, shares outstanding (in shares) |  |  |  | 37,973,991 | 37,207,799 |  |
Preferred stock, shares authorized (in shares) |  |  |  | 5,000,000 | 5,000,000 |  | 5,000,000
Preferred stock, par value (in dollars per share) |  |  |  | $ 0.001 | $ 0.001 |  | $ 0.001
Preferred stock, shares issued (in shares) |  |  |  | 0 | 0 |  |
Preferred stock, shares outstanding (in shares) |  |  |  | 0 | 0 |  |
Warrant liabilities fair value adjustment |  |  |  | $ (13,812) | $ 3,166 |  |
Warrant liabilities |  |  |  | $ 13,700 | $ 21,800 |  |
Warrants to purchase common stock associated with Danforth Advisors |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  | 50,000 |  |  |  |
Exercise price of warrants (in dollars per share) |  |  | $ 5.5 |  |  |  |
Warrant expiration period |  |  | 5 years |  |  |  |
Cantor Fitzgerald Co | Common Stock Sales Agreement |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ 0.001 |  |  |  |  |  |
Cantor Fitzgerald Co | Sales Agreement |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock issued, net of expenses (in shares) |  |  |  | 0 |  |  |
Maximum | Cantor Fitzgerald Co | Common Stock Sales Agreement |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock issued, net of expenses (in shares) | 50,000,000 |  |  |  |  |  |
Common Stock |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock, shares outstanding (in shares) |  |  |  | 37,973,991 | 37,207,799 | 32,682,342 |
Common stock issued, net of expenses (in shares) |  |  |  |  | 4,150,400 |  |
December 2020 Public Offering | Pre-funded Warrants |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  |  |  | 7,516,267 | 3,200,000 |  |
April 2022 Public Offering |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock issued, net of expenses (in shares) |  | 3,333,333 |  |  |  |  |
Pre-funded warrants were exercised for proceeds |  |  |  | $ 0 | $ 4,150 |  |
April 2022 Public Offering | Pre-funded Warrants |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Common stock, par value (in dollars per share) |  | $ 0.001 |  |  |  |  |
Common stock issued, net of expenses (in shares) |  |  |  | 0 | 4,150,400 |  |
Number of warrants issued to purchase common stock (in shares) |  | 11,666,667 |  | 7,516,267 | 3,200,000 |  |
Public offering price |  | $ 2.999 |  |  |  |  |
April 2022 Public Offering | Series 1 Warrant |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 0.001 |  |  |  |  |
April 2022 Public Offering | Series 1 Warrant | Maximum |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 11,666,667 |  |  |  |  |
April 2022 Public Offering | Series 2 Warrant |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 3.45 |  |  |  |  |
Warrant term |  | 7 years |  |  |  |  |
April 2022 Public Offering | Series 2 Warrant | Maximum |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Number of shares received per warrant (in shares) |  | 15,000,000 |  |  |  |  |
April 2022 Public Offering | Common Stock |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Public offering price |  | $ 3.00 |  |  |  |  |
April 2022 Public Offering | Warrant | Maximum |  |  |  |  |  |  |
Schedule Of Capitalization Equity [Line Items] |  |  |  |  |  |  |
Number of warrants issued to purchase common stock (in shares) |  | 15,000,000 |  |  |  |  |

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