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Stock-Based Compensation - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Dec. 06, 2022
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Common stock shares reserved for future issuance 2,571,610      
Number of options, granted 180,231      
Weighted average exercise price, granted $ 17.34      
Common stock, shares issued 5,661,933   84,165  
Stock-based compensation expense $ 11,126 $ 335    
Acceleration of stock awards 10,500      
Research and Development        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense 2,080 224    
General and Administrative        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense 9,046 $ 111    
Graybug        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Acceleration of stock awards 10,500      
Graybug | Research and Development        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense 1,900      
Graybug | General and Administrative        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense $ 8,600      
2006 Equity Incentive Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expiration period 10 years      
Award vesting rights, percentage 25.00%      
Award vesting period 1 year      
Vesting period 36 months      
Amendment to 2006 Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Common stock shares reserved for future issuance       180,245
2023 Equity Incentive Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Common stock shares reserved for future issuance 1,000,000      
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan 5.00%      
2023 Employee Stock Purchase Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Common stock shares reserved for future issuance 65,000      
Weighted averagefair value options, granted $ 11.94 $ 6.60    
Total fair value of shares vested $ 10,900 $ 200    
Common stock, shares issued 195,000      
Stock issued on exercise of stock options, Shares 0      
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan 1.00%      
Stock Issued 0      
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards $ 3,500      
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards weighted-average term of recognition 2 years 8 months 12 days