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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Operating activities:      
Net loss $ (19,288) $ (3,630)  
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation expense 11,126 335  
Depreciation and amortization 13 13  
Change in the fair value of warrant liability (1,146) (581)  
Change in the fair value of convertible promissory notes (2,022)    
Non-cash interest expense 110    
Accretion of discount on short-term investment (2)    
Changes in operating assets and liabilities:      
Prepaid expenses and other current and non-current assets 129 66  
Accounts payable (1,040) (657)  
Accrued expenses and other liabilities 6,765 828  
Net cash used in operating activities (5,355) (3,626)  
Investing activities:      
Purchases of property and equipment   (4)  
Maturity of investments 4,750    
Net cash provided by (used in) investing activities 4,750 (4)  
Financing activities:      
Proceeds from issuance of common stock, net of issuance costs 10,340    
Acquisition of stock of Graybug, net of cash 14,856    
Merger transaction costs (1,681)    
Proceeds from exercise of stock options   1  
Net cash provided by financing activities 23,515 1  
Net increase (decrease) in cash and cash equivalents 22,910 (3,629)  
Cash, cash equivalents and restricted cash at beginning of period 1,476 4,761 $ 4,761
Cash and cash equivalents at end of period 24,386 $ 1,132 $ 1,476
Supplemental cash flow information:      
Conversion of Series A, B, C-1, C-2 and D convertible preferred stock to common stock 62,071    
Issuance of common stock to Graybug stockholders as a result of the Merger 29,218    
Short-term investments assumed in the Merger 9,776    
Prepaid expenses and other current assets assumed in the Merger 2,096    
Accounts payable and accrued liabilities assumed in the Merger 2,258    
Conversion of C-2 warrants to common stock 442    
Conversion of convertible promissory notes to common stock 3,245    
Conversion of convertible promissory note warrants to common stock 841    
Merger transaction costs in accounts payable 206    
Merger transaction costs in accrued expenses 2,703    
Restricted stock units net settlement 297    
Reclassification of warrant liability to equity $ 216