Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan.

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Percentage of vesting of award under share-based payment arrangement.

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Stock-based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Mar. 20, 2023
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock shares reserved for future issuance	2,475,016
Common stock, shares issued	5,754,505	84,165
Number of options, forfeited	96,594
Stock-based compensation expense	$ 12,039	$ 1,401
Acceleration of stock awards	10,500
Research and Development
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation expense	2,449	499
General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation expense	9,590	$ 902
Graybug
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Acceleration of stock awards	10,500
Graybug \| Research and Development
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation expense	1,900
Graybug \| General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation expense	$ 8,600
2006 Equity Incentive Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expiration period	10 years
Award vesting rights, percentage	25.00%
Award vesting period	1 year
Vesting period	36 months
2023 Equity Incentive Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock shares reserved for future issuance	394,309		1,000,000
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan	5.00%
Number of options, forfeited	96,594
Shares available for grant (shares)	394,309
2023 Employee Stock Purchase Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock shares reserved for future issuance	65,000
Weighted averagefair value options, granted	$ 2.34	$ 12.85
Total fair value of shares vested	$ 11,900	$ 1,700
Common stock, shares issued	195,000
Exercise of common stock options, Shares	0
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan	1.00%
Stock Issued	0
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards	$ 2,300
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards weighted-average term of recognition	2 years 4 months 24 days