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Stock-based Compensation - Additional Information (Details) - USD ($) |  | 12 Months Ended |  |
--- | --- | --- | --- | ---
Jan. 01, 2024 | Dec. 31, 2024 | Dec. 31, 2023 | Mar. 28, 2024 | Mar. 20, 2023
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Common stock shares reserved for future issuance |  | 7,107,023 |  |  |
Common stock, shares issued |  | 13,481,917 | 5,754,505 |  |
Stock issued on exercise of stock options, Shares |  | 12,852 |  |  |
Number of options, forfeited |  | 228,475 |  |  |
Acceleration of stock awards |  | $ 10,500,000 |  |  |
Number of options, granted |  | 1,326,500 |  |  |
Restricted Stock Units |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Aggregate grant date fair value of RSUs vested |  | $ 0 |  |  |
Research and Development |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Stock-based compensation expense |  | 840,000 | $ 2,449,000 |  |
General and Administrative |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Stock-based compensation expense |  | 1,473,000 | 9,590,000 |  |
Graybug |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Acceleration of stock awards |  | $ 10,500,000 | 10,500,000 |  |
Graybug | Research and Development |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Stock-based compensation expense |  |  | 1,900,000 |  |
Graybug | General and Administrative |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Stock-based compensation expense |  |  | $ 8,600,000 |  |
2020 Equity Incentive Plan |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Number of shares unavailable for grant (shares) |  | 223,743 |  |  |
2023 Equity Incentive Plan |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Common stock shares reserved for future issuance |  | 807,414 |  | 1,500,000 | 1,000,000
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan |  | 5.00% |  |  |
Number of options, forfeited |  | 228,475 |  |  |
Increase in number of shares reserved for issuance | 287,725 |  |  |  |
Shares available for grant (shares) |  | 820,266 |  |  |
2023 Employee Stock Purchase Plan |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |
Common stock shares reserved for future issuance |  | 122,545 |  |  |
Common stock shares reserved for future issuance, initial |  | 65,000 |  |  |
Weighted average fair value options, granted |  | $ 4.14 | $ 2.34 |  |
Total fair value of shares vested |  | $ 5,000,000 | $ 11,900,000 |  |
Common stock, shares issued |  | 195,000 |  |  |
Stock issued on exercise of stock options, Shares |  | 12,852 |  |  |
Percentage of aggregate number of shares of common stock outstanding on last day of preceding year added to plan |  | 1.00% |  |  |
Increase in number of shares reserved for issuance |  | 57,545 |  |  |
Stock Issued |  | 0 |  |  |
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards |  | $ 4,700,000 |  |  |
Total unrecognized stock-based compensation expenses related to outstanding unvested stock awards weighted-average term of recognition |  | 2 years 9 months 18 days |  |  |
Number of options, granted |  | 1,326,500 |  |  |

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