<SEC-DOCUMENT>0001649739-22-000042.txt : 20220128
<SEC-HEADER>0001649739-22-000042.hdr.sgml : 20220128
<ACCEPTANCE-DATETIME>20220128125630
ACCESSION NUMBER:		0001649739-22-000042
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20220127
FILED AS OF DATE:		20220128
DATE AS OF CHANGE:		20220128

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Jaber Brandi Nicole
		CENTRAL INDEX KEY:			0001885458

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41068
		FILM NUMBER:		22566845

	MAIL ADDRESS:	
		STREET 1:		700 CENTRAL AVE
		CITY:			ST PETERSBURG
		STATE:			FL
		ZIP:			33701

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BayFirst Financial Corp.
		CENTRAL INDEX KEY:			0001649739
		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
		IRS NUMBER:				593665079
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		700 CENTRAL AVENUE
		STREET 2:		SUITE 102
		CITY:			ST PETERSBURG
		STATE:			FL
		ZIP:			33701
		BUSINESS PHONE:		727-399-5600

	MAIL ADDRESS:	
		STREET 1:		700 CENTRAL AVENUE
		STREET 2:		SUITE 102
		CITY:			ST PETERSBURG
		STATE:			FL
		ZIP:			33701

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	First Home Bancorp Inc
		DATE OF NAME CHANGE:	20150731
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wf-form4_164339257522460.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2022-01-27</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001649739</issuerCik>
        <issuerName>BayFirst Financial Corp.</issuerName>
        <issuerTradingSymbol>BAFN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001885458</rptOwnerCik>
            <rptOwnerName>Jaber Brandi Nicole</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>700 CENTRAL AVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PETERSBURG</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33701</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Executive Vice President</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2022-01-27</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1250</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3123.8322</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Restricted stock awards granted will vest in five equal annual installments beginning one year after the date of grant. In addition, all unvested Restricted Shares will automatically vest in full immediately upon attainment of Normal Retirement Age. Normal Retirement Age shall be 62.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Richard Pearlman, Attorney-in-Fact</signatureName>
        <signatureDate>2022-01-28</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
