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Research and development expenses (Tables) | 12 Months Ended
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Dec. 31, 2022
Research and development expenses |
Schedule of research and development expenses | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | For the Year Ended December 31,
(in thousands) |  | 2022 |  | 2021 |  | 2020
Pre-clinical and clinical trial expenses | ​ | $ | 28,178 | ​ | $ | 14,188 | ​ | $ | 11,325
Personnel-related expenses | ​ | ​ | 6,150 | ​ | ​ | 4,955 | ​ | ​ | 2,276
Research and development activities expenses | ​ | ​ | 2,241 | ​ | ​ | 1,843 | ​ | ​ | 1,022
Share-based compensation expense | ​ | ​ | 1,975 | ​ | ​ | 788 | ​ | ​ | 232
Facilities and other research and development expenses | ​ | ​ | 1,546 | ​ | ​ | 814 | ​ | ​ | 643
VUmc and other license expenses | ​ | ​ | 15 | ​ | ​ | 14,357 | ​ | ​ | 203
​ | ​ | $ | 40,105 | ​ | $ | 36,945 | ​ | $ | 15,701
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