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Share capital, share premium and other capital reserves (Tables) | 12 Months Ended
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Dec. 31, 2022
Share capital, share premium and other capital reserves |
Schedule of share capital | The following table provides information about the Company’s share capital as of December 31, 2022, 2021 and 2020:
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
(in thousands, except | ​ | Authorized | ​ | Issued and fully paid | ​ | Additional paid-in capital | ​ | Share premium
for share and per | ​ | December 31, | ​ | December 31, | ​ | December 31, | ​ | December 31,
share amounts) |  | 2022 |  | 2021 |  | 2020 |  | 2022 |  | 2021 |  | 2020 |  | 2022 |  | 2021 |  | 2020
Common shares of $0.01 each | ​ | — |  | — | ​ | 447,525 |  | — |  | — |  | 281,775 |  | $ | — |  | $ | — | ​ | $ | —
Preference Series A shares of $0.01 each | ​ | — |  | — | ​ | 1,755,845 |  | — |  | — |  | 1,037,595 |  | ​ | — |  | ​ | — | ​ | ​ | 722
Preference Series B shares of $0.01 each | ​ | — |  | — | ​ | 3,899,766 |  | — |  | — |  | 3,899,766 |  | ​ | — |  | ​ | — | ​ | ​ | 18,340
Preference Series C shares of $0.01 each | ​ | — |  | — | ​ | 4,133,805 |  | — |  | — |  | 4,133,805 |  | ​ | — |  | ​ | — | ​ | ​ | 22,026
Preference shares of $0.01 each | ​ | — |  | — | ​ | 9,789,416 |  | — |  | — |  | 9,071,166 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 41,088
Preference shares of $0.14 each | ​ | 45,000,000 | ​ | 45,000,000 | ​ | — | ​ | — | ​ | — | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | —
Common shares of $0.14 each | ​ | 45,000,000 | ​ | 45,000,000 | ​ | — | ​ | 26,289,087 | ​ | 25,775,538 | ​ | — | ​ | ​ | 194,424 | ​ | ​ | 192,270 | ​ | ​ | —
​ | ​ | 90,000,000 |  | 90,000,000 | ​ | 10,236,941 |  | 26,289,087 |  | 25,775,538 | ​ | 9,352,941 | ​ | $ | 194,424 | ​ | $ | 192,270 | ​ | $ | 41,088
​
Schedule of major shareholders on a non-diluted basis | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | As of December 31, | ​
​ |  | 2022 |  | 2021 |
Gilde Healthcare |  | 20.6 | % | 21.0 | %
Versant Venture Capital VI, L.P. |  | 17.5 | % | 17.8 | %
Novo Holdings A/S |  | 12.7 | % | 12.9 | %
Redmile Biopharma Investments |  | 10.6 | % | 10.8 | %
Sanofi Foreign Participations B.V. |  | 7.3 | % | 7.4 | %
Ysios Capital Partners, SGECR,S.A.U. |  | — | % | 6.2 | %
Other shareholders |  | 31.3 | % | 23.9 | %
​ |  | 100.0 | % | 100.0 | %

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