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Research and development expenses (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Research and development expenses
Pre-clinical and clinical trial expenses	$ 28,178	$ 14,188	$ 11,325
Personnel-related expenses	6,150	4,955	2,276
Research and development activities expenses	2,241	1,843	1,022
Share-based compensation expense	1,975	788	232
Facilities and other research and development expenses	1,546	814	643
VUmc and other license expenses	15	14,357	203
Total research and development expenses	40,105	36,945	15,701
Government grants	$ 1,600	$ 1,700	$ 1,000

X

- Definition

The amount of assistance by government in the form of transfers of resources to an entity in return for past or future compliance with certain conditions relating to the operating activities of the entity, recognised as deferred income. They exclude those forms of government assistance that cannot reasonably have a value placed upon them and transactions with government that cannot be distinguished from the normal trading transactions of the entity. [Refer: Deferred income other than contract liabilities; Government [member]]

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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X

- Definition

The amount of expenditure directly attributable to research or development activities, recognised in profit or loss.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition

The amount of facilities and other research and development expenses directly attributable to research or development activities, recognised in profit or loss.

+ References

No definition available.

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- Definition

The amount of personnel-related expenses directly attributable to research or development activities, recognised in profit or loss.

+ References

No definition available.

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- Definition

The amount of pre-clinical and clinical trial expenses directly attributable to research or development activities, recognised in profit or loss.

+ References

No definition available.

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- Definition

The amount of research and development activities expenses directly attributable to research or development activities, recognised in profit or loss.

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- Definition

The amount of share-based compensation expense directly attributable to research or development activities, recognised in profit or loss.

+ References

No definition available.

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- Definition

The amount of license expenses directly attributable to research or development activities, recognised in profit or loss.

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No definition available.

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