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Statements of Cash Flows - USD ($)
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:    
Net loss $ (7,898,000) $ (7,296,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Common stock issued for services 157,000 222,000
Share based payments 797,000 365,000
Depreciation and amortization 200,000 243,000
Abandonment of capitalized patents pending 593,000 262,000
Deferred rent (13,000) 2,000
Change in operating assets and liabilities:    
Prepaid expenses (94,000) 9,000
Accounts payable 242,000 (44,000)
Accrued compensation (245,000) 768,000
Net cash used in operating activities (6,261,000) (5,469,000)
Cash flows from investing activities:    
Acquisition of fixed assets (49,000) (78,000)
Disbursements for patents and other intangible assets (1,113,000) (1,176,000)
Net cash used in investing activities (1,162,000) (1,254,000)
Cash flows from financing activities:    
Proceeds from issuance of common stock for cash, net of offering costs 16,279,000 5,780,000
Proceeds from exercise of stock options 284,000 100,000
Net cash provided by financing activities 16,563,000 5,880,000
Net increase (decrease) in cash and cash equivalents 9,140,000 (843,000)
Cash and cash equivalents, beginning of year 1,845,000 2,688,000
Cash and cash equivalents, end of year $ 10,985,000 $ 1,845,000