Collaborative Arrangement, Duration Of Agreement

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- Definition

Collaborative Arrangement, Equity Interest Acquired

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- Definition

Collaborative Arrangement, Maximum Obligation For Research And Development

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- Definition

Collaborative Arrangement, Minimum Obligation For Research And Development

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- Definition

Collaborative Arrangement, Number of Collaboration Project, Completed

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- Definition

Collaborative Arrangement, Number of Collaboration Project, In Progress

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- Definition

Collaborative Arrangement, Outstanding Commitment

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- Definition

Collaborative Arrangement, Payment for Additional Development and Commercialization

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- Definition

Collaborative Arrangement, Payment for Research and Development Agreement

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- Definition

Collaborative Arrangement, Revenue Sharing, Percentage

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- Definition

Collaborative Arrangements And Noncollaborative Arrangement Transaction [Line Items]

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- Definition

Prepaid Research and Development

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- Definition

Research and Development Expense, Related Party

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Research and Collaboration Agreements (Details) € in Thousands			3 Months Ended
	Jun. 30, 2017 USD ($)	Jun. 30, 2017 EUR (€)	Mar. 31, 2019 USD ($) collaboration_project	Mar. 31, 2018 USD ($)	Dec. 31, 2018 USD ($)	Jun. 30, 2017 EUR (€)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Duration of agreement	2 years	2 years
Payment for research and development agreement	$ 1,100,000	€ 1,000
Prepaid research and development \| $			$ 200,000		$ 300,000
Research and development - related party \| $			389,473	$ 392,549
RSA
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Payment for research and development agreement \| €		€ 1,000
Payment for additional development and commercialization \| €						€ 1,500
RSA \| Minimum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue sharing, percentage	50.00%	50.00%
RSA \| Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue sharing, percentage	75.00%	75.00%
RSA \| BDI Holdings
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Equity interest acquired	16.10%	16.10%
RSA \| VLPbio
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Equity interest acquired	3.30%	3.30%
RSA \| BDI
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Duration of agreement	2 years	2 years
Obligation for payment for research and development, minimum \| €						936
Obligation for payment for research and development, maximum \| €						€ 8,000
RSA \| BDI \| Minimum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue sharing, percentage	50.00%	50.00%
RSA \| BDI \| Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue sharing, percentage	75.00%	75.00%
SFA
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Duration of agreement	2 years	2 years
Obligation for payment for research and development, minimum \| $	$ 1,000,000
Outstanding commitment \| $	$ 1,000,000		$ 0
Number of collaboration project, completed \| collaboration_project			4
Number of collaboration project, in progress \| collaboration_project			1