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v3.20.1

CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018
Cash flows from operating activities |  |
Net loss | $ (8,307,965) | $ (5,691,756)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 1,171,079 | 467,203
Amortization of held-to-maturity securities, net | 198,208 | 676,644
Foreign currency exchange loss (gain), net | 27,725 | 20,778
Changes in operating assets and liabilities: |  |
Interest receivable | (35,471) | 195,601
Accounts receivable | (252,772) | (59,984)
Income tax receivable | 506,866 | (1,007,482)
Prepaid research and development | 253,446 | 913,013
Prepaid expenses and other current assets | (105,707) | (17,395)
Accounts payable | 657,658 | (195,755)
Accrued expenses | 166,399 | 251,617
Deferred research and development obligations | (62,358) | 141,002
Income taxes payable | 0 | (100,675)
Net cash used in operating activities | (5,782,892) | (4,407,189)
Cash flows from investing activities |  |
Purchases of held-to-maturity investment securities | (47,615,550) | (49,734,681)
Proceeds from maturities of investment securities | 55,323,000 | 53,063,000
Net cash provided by investing activities | 7,707,450 | 3,328,319
Cash flows from financing activities |  |
Repurchases of common stock | 0 | (2,304,042)
Proceeds from exercise of options | 550,188 | 4,500
Net cash provided by (used in) financing activities | 550,188 | (2,299,542)
Effect of exchange rate changes on cash | (37,516) | (21,622)
Net decrease in cash and cash equivalents | 2,437,230 | (3,400,034)
Cash and cash equivalents at beginning of period | 2,386,314 | 5,786,348
Cash and cash equivalents at end of period | 4,823,544 | 2,386,314
Supplemental cash flow information |  |
Cash received from income tax refund | $ 506,866 | $ 0

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