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Note 1 - Organization and Summary of Significant Accounting Policies (Details Textual) | 12 Months Ended
--- | ---
Dec. 31, 2020 USD ($) shares | Dec. 31, 2019 USD ($) shares
Number of Research Organizations | 2 |
Number of Operating Segments | 1 |
Revenue from Contract with Customer, Excluding Assessed Tax, Total | $ 1,601,921 | $ 1,681,076
Accounts Receivable, Allowance for Credit Loss, Ending Balance | $ 0 | $ 0
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) | shares | 4,638,390 | 3,860,390
Alphazyme [Member] |  |
Equity Securities without Readily Determinable Fair Value, Amount | $ 284,709 |
Customer Concentration Risk [Member] | Revenue Benchmark [Member] |  |
Concentration Risk, Number of Customers | 14 | 10
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Non-US [Member] |  |
Concentration Risk, Number of Customers | 7 | 4
Concentration Risk, Percentage | 49.70% | 71.50%
Revenue from Contract with Customer, Excluding Assessed Tax, Total | $ 796,000 | $ 1,202,000
Customer Concentration Risk [Member] | Accounts Receivable [Member] |  |
Concentration Risk, Number of Customers | 9 | 5
Customer Concentration Risk [Member] | Accounts Receivable [Member] | Non-US [Member] |  |
Concentration Risk, Percentage | 41.60% | 69.50%
Revenue from Contract with Customer, Excluding Assessed Tax, Total | $ 123,000 | $ 388,000
Customer Concentration Risk [Member] | Contract Research Organizations [Member] |  |
Concentration Risk, Percentage | 91.60% | 86.60%
Customer Concentration Risk [Member] | Accounts Payable [Member] | Contract Research Organizations [Member] |  |
Concentration Risk, Percentage | 68.10% | 74.90%
Accounts Payable, Total | $ 690,000 | $ 706,000

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