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Note 1 - Organization and Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2020
Notes Tables  
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
  

December 31,

 
  

2020

  

2019

 

Billed receivable

 $130,532  $432,546 

Unbilled receivable

  163,667   125,984 
  $294,199  $558,530 
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
  

December 31,

 
  

2020

  

2019

 

Prepaid insurance

 $204,988  $173,890 

Prepaid expenses - various

  72,403   101,221 

Prepaid taxes

  3,164   2,888 
  $280,555  $277,999 
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
  

December 31,

 
  

2020

  

2019

 

Research and development expenses

 $904,572  $766,001 

Legal expenses

  24,496   26,994 

Other

  84,031   150,383 
  $1,013,099  $943,378 
Schedule of Accrued Liabilities [Table Text Block]
  

December 31,

 
  

2020

  

2019

 

Employee wages and benefits

 $447,881  $474,388 

Research and development expenses

  28,508   69,795 

Other

  13,367   21,820 
  $489,756  $566,003 
Schedule of Research and Development Costs [Table Text Block]
  

Years Ended December 31,

 
  

2020

  

2019

 

Outside contracted services

 $3,302,034  $2,578,507 

Contracted services - related party

     868,720 

Personnel related costs

  531,405   423,898 

Facilities, overhead and other

  34,682   85,192 
  $3,868,121  $3,956,317