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Note 4 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Notes Tables  
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
  

Years Ended December 31,

 
  

2020

  

2019

 

U.S. operations

 $(9,246,122) $(8,274,712)

Foreign operations

  (47,833)  (22,947)

Total loss before provision for income taxes

 $(9,293,955) $(8,297,659)
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
  

Years Ended December 31,

 
  

2020

  

2019

 

Tax at U.S. statutory rate

  (21.00)%  (21.00)%

State taxes, net of federal benefit

  (3.60)  (4.61)

Non-deductible items

  (0.45)  (6.49)

Change in valuation allowance

  24.19   30.99 

True-up adjustment

  1.33   0.18 

Foreign operations

  (0.13)  (0.07)

Change in tax rates

     1.00 

Other

  (0.34)   

Effective income tax rate

  %  %
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
  

December 31,

 
  

2020

  

2019

 

Stock option expense

 $689,600  $275,000 

NOL carryforward

  7,080,600   5,214,200 

Research and development credits

  1,656,500   1,656,500 
Unrealized gain from investment in Alphazyme  (69,800)   

Other

  7,900   4,400 

Deferred tax asset, net of deferred tax liabilities

  9,364,800   7,150,100 

Valuation allowance

  (9,364,800)  (7,150,100)

Net deferred tax asset

 $  $