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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Cash flows from operating activities    
Net loss $ (7,141,123) $ (4,865,561)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 867,191 863,552
Amortization of held-to-maturity securities, net 159,481 229,919
Provision for contract losses 0 74,955
Foreign currency exchange loss (gain), net 46,079 50,204
Changes in operating assets and liabilities:    
Interest receivable (51,066) 103,576
Accounts receivable (36,049) 32,112
Prepaid expenses and other current assets 179,617 (321,533)
Accounts payable 1,427,809 154,484
Accrued expenses 104,546 (188,369)
Deferred research and development obligation 135,732 (37,268)
Net cash used in operating activities (4,307,783) (3,903,929)
Cash flows from investing activities    
Purchases of held-to-maturity investment securities (11,283,940) (14,677,156)
Proceeds from maturities of investment securities 8,000,000 25,305,000
Net cash (used in) provided by investing activities (3,283,940) 10,627,844
Cash flows from financing activities    
Proceeds from exercise of options 986,140 230,743
Net cash provided by financing activities 986,140 230,743
Effect of exchange rate changes on cash (12,636) 3,347
Net (decrease) increase in cash and cash equivalents (6,618,219) 6,958,005
Cash and cash equivalents at beginning of period 20,637,045 4,823,544
Cash and cash equivalents at end of period $ 14,018,826 $ 11,781,549