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Note 3 - Research and Collaboration Agreements, Sublicense Agreements, and Investments in Privately-held Companies (Details Textual)				1 Months Ended	3 Months Ended		9 Months Ended
	Jun. 24, 2020	Jun. 30, 2017 USD ($)	Jun. 30, 2017 EUR (€)	Aug. 31, 2021 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2020 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2020 USD ($)	Jul. 26, 2021	Jul. 08, 2021 shares	Dec. 31, 2020 USD ($)	Dec. 01, 2020	Apr. 26, 2019	Jun. 30, 2017 EUR (€)
Cost of Goods and Services Sold, Total					$ 392,544	$ 266,929	$ 1,612,810	$ 1,169,351
Collaborative Arrangement, Payment for Research and Development Agreement		$ 1,100,000
ID Biologics Inc [Member]
Cost of Goods and Services Sold, Total					$ 76,000		$ 132,000
Novovet [Member]
Equity Method Investment, Ownership Percentage													20.00%
Alphazyme [Member]
Sale of Stock, Percentage of Ownership after Transaction	2.50%
Equity Securities without Readily Determinable Fair Value, Amount											$ 284,709
BDI Holdings [Member]
Proceeds from Sales of Business, Affiliate and Productive Assets				$ 1,600,000
Research Services Agreement [Member]
Collaborative Arrangement, Payment for Additional Development and Commercialization | €														€ 1,500,000
Service Framework Agreement [Member]
Collaborative Arrangement, Minimum Obligation For Research and Development		$ 1,000,000.0
Collaborative Arrangement, Duration Of Agreement (Year)		2 years	2 years
Collaborative Arrangement, Outstanding Commitment		$ 1,000,000.0
BDI Holdings [Member]
Ownership Percentage									16.10%
VLPBio Member
Ownership Percentage									3.30%
Alphazyme [Member]
Ownership Percentage												1.99%
ID Biologics Inc [Member]
Investment Owned, Balance, Shares (in shares) | shares										129,661
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners										0.37%
Research Services Agreement [Member]
Collaborative Arrangement, Payment for Research and Development Agreement | €			€ 1,000,000.0
Research Services Agreement [Member] | BDI Holdings [Member]
Collaborative Arrangement, Equity Interest Acquired		16.10%	16.10%
Collaborative Arrangement, Minimum Obligation For Research and Development | €														936,000
Collaborative Arrangement, Duration Of Agreement (Year)		2 years	2 years
Collaborative Arrangement, Maximum Obligation For Research and Development | €														8,000,000.0
Research Services Agreement [Member] | BDI Holdings [Member] | Minimum [Member]
Collaborative Arrangement, Minimum Obligation For Research and Development | €														€ 1,000,000
Collaborative Arrangement, Revenue Sharing, Percentage		50.00%	50.00%
Research Services Agreement [Member] | BDI Holdings [Member] | Maximum [Member]
Collaborative Arrangement, Revenue Sharing, Percentage		75.00%	75.00%
Research Services Agreement [Member] | VLPBio Member
Collaborative Arrangement, Equity Interest Acquired		3.30%	3.30%

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