<SEC-DOCUMENT>0001437749-21-017633.txt : 20210727
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<ACCEPTANCE-DATETIME>20210727083302
ACCESSION NUMBER:		0001437749-21-017633
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		16
CONFORMED PERIOD OF REPORT:	20210726
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20210727
DATE AS OF CHANGE:		20210727

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DYADIC INTERNATIONAL INC
		CENTRAL INDEX KEY:			0001213809
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				450486747
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32513
		FILM NUMBER:		211115980

	BUSINESS ADDRESS:	
		STREET 1:		140 INTRACOASTAL POINTE DRIVE
		STREET 2:		SUITE 404
		CITY:			JUPITER
		STATE:			FL
		ZIP:			33477
		BUSINESS PHONE:		561-743-8333

	MAIL ADDRESS:	
		STREET 1:		140 INTRACOASTAL POINTE DRIVE
		STREET 2:		SUITE 404
		CITY:			JUPITER
		STATE:			FL
		ZIP:			33477

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CCP WORLDWIDE INC
		DATE OF NAME CHANGE:	20030110
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<div style="font-family: &quot;Times New Roman&quot;; font-size: 16pt; margin: 0pt; text-align: center;"><b>UNITED STATES</b></div>

<div style="font-family: &quot;Times New Roman&quot;; font-size: 16pt; margin: 0pt; text-align: center;"><b>SECURITIES AND EXCHANGE COMMISSION</b></div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>Washington, D.C. 20549</b></div>

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<div style="font-family: &quot;Times New Roman&quot;; font-size: 18pt; margin: 0pt; text-align: center;"><b>FORM <ix:nonNumeric contextRef="d20218K" name="dei:DocumentType"><b>8-K</b></ix:nonNumeric></b></div>

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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>CURRENT REPORT</b></div>

<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>Pursuant to Section 13 or 15(d) of the</b></div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>Securities Exchange Act of 1934</b></div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>&#xa0;</b></div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>Date of Report (date of earl<span style="background-color:#ffffff;">iest event reported):&#xa0;</span><ix:nonNumeric contextRef="d20218K" format="ixt:datemonthdayyearen" name="dei:DocumentPeriodEndDate"><b><span style="text-decoration: underline;"><span style="font-family:Times New Roman;font-size:12pt;"><span style="background-color:#ffffff;">July&#xa0;26, 2021</span></span></span></b></ix:nonNumeric></b></div>

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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:18pt;margin:0pt;text-align:center;"><ix:nonNumeric contextRef="d20218K" name="dei:EntityRegistrantName"><b>Dyadic International, Inc.</b></ix:nonNumeric></div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;">(Exact name of registrant as specified in its charter)</div>

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<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:left;">&#xa0;</div>

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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:0pt;margin-right:2.25pt;margin-top:0pt;text-align:center;">(State or other jurisdiction of incorporation or organization)</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:0pt;margin-right:2.25pt;margin-top:0pt;text-align:center;">(Commission File Number)</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:0pt;margin-right:2.25pt;margin-top:0pt;text-align:center;">(I.R.S. Employer Identification Number)</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt 1.1pt;text-align:center;">(Registrant&#8217;s telephone number, including area code)</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt 2.25pt;text-align:center;"><b>N/A</b></div>

			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt 2.25pt;text-align:center;"><b>(Former Name or Former Address, if Changed Since Last Report)</b></div>
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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:left;">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</div>

<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</div>
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			<td style="vertical-align:middle;width:7%;">
			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt 1.1pt;text-align:center;"><ix:nonNumeric contextRef="d20218K" format="ixt-sec:boolballotbox" name="dei:SolicitingMaterial">&#9744;</ix:nonNumeric></div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</div>
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			<td style="vertical-align:middle;width:7%;">
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</div>
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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:left;">&#xa0;</div>

<table border="0" cellpadding="0" cellspacing="0" style="width:100%;text-indent:0;font-family:'Times New Roman', Times, serif;font-size:10pt;">

		<tbody><tr>
			<td style="vertical-align:bottom;width:100.5%;">
			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR &#167;230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR &#167;240.12b-2).</div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:0pt;margin-right:2.25pt;margin-top:0pt;text-align:right;">Emerging growth company <ix:nonNumeric contextRef="d20218K" format="ixt-sec:boolballotbox" name="dei:EntityEmergingGrowthCompany">&#9744;</ix:nonNumeric></div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. &#9744;</div>
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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:left;">Securities registered pursuant to Section 12(b) of the Act</div>

<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">&#xa0;</div>

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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:0pt;margin-right:2.25pt;margin-top:0pt;text-align:left;">Title of each class</div>
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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left"><b>Item 1.01. Entry into a Material Definitive Agreement.</b></div>

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<div style="font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; margin: 0pt; text-align: left; text-indent: 27pt;">On July 26, 2021, Dyadic International, Inc. (&#8220;Dyadic&#8221; or the &#8220;Company&#8221;) entered into (i) a Sale and Purchase of Shares Agreement under which the Company agreed to sell its equity interest in Biotechnology Developments for Industry, S.L. (the &#8220;BDI Agreement&#8221;), and (ii) a Sale and Purchase of Shares Agreement under which the Company agreed to sell its equity interest in VLP The Vaccine Company, S.L.U. (the &#8220;VLP Agreement&#8221; and together with the BDI Agreement, the &#8220;BDI Sale&#8221;). After taking into account the adjustments for transaction and legal expenses, payments to the Company were approximately 1.3 million euros in connection with the closing of the BDI Sale.&#xa0;</div>

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<div style="font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; margin: 0pt; text-align: left; text-indent: 27pt;">In connection with the BDI Sale, on July 26, 2021, the Company also entered into an amendment to the Service Framework Agreement (the &#8220;Amended SFA&#8221;) with Biotechnology Development for Industry in Pharmaceuticals, S.L.U (&#8220;BDI Pharma&#8221;).&#xa0; Under the Amended SFA, the Company maintains the right to engage in research and development projects at BDI Pharma until June 30, 2025, with the non-compete term extending to June 30, 2030, without any other material terms and conditions changed.&#xa0;</div>

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<div style="font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; margin: 0pt; text-align: left; text-indent: 27pt;">The BDI Sale and the Amended SFA, were previously approved by Dyadic&#8217;s Board of Directors.</div>

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<div style="font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; margin: 0pt; text-align: left; text-indent: 27pt;">The foregoing descriptions of the BDI Agreement, the VLP Agreement and the Amended SFA are only summaries of the material terms thereof, do not purport to be complete and are qualified in their entirety by reference to the full text of the agreements, which are filed as Exhibits 10.1, 10.2 and 10.3 to this Current Report on Form 8-K and incorporated by reference herein.</div>

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			<div style="font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; margin: 0pt 0pt 0pt 2pt; text-align: left;"><b>Item 9.01 Financial Statements and Exhibits</b></div>
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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">The following exhibit is being filed&#xa0;herein:</div>
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			<td style="vertical-align: top; width: 24.3%; text-align: center;">10.1</td>
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			<td style="vertical-align:bottom;width:75.4%;"><a href="ex_257726.htm" style="-sec-extract:exhibit;">BDI sale agreement dated July 26, 2021</a></td>
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			<td style="vertical-align:bottom;width:75.4%;"><a href="ex_267318.htm" style="-sec-extract:exhibit;">VLP sale agreement dated July 26, 2021</a></td>
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			<td style="vertical-align:bottom;width:75.4%;"><a href="ex_267349.htm" style="-sec-extract:exhibit;">Amendment No. 1 dated July 26, 2021 to the Service Framework Agreement dated June 30, 2017</a></td>
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			<td style="vertical-align: top; width: 24.3%; text-align: center;">104</td>
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<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt;text-align:center;"><b>SIGNATURE</b></div>

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<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin:0pt 14.7pt;text-align:left;text-indent:36pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</div>

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<div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">Date: July 27, 2021</div>

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			<div style="font-family:'Times New Roman', Times, serif;font-size:10pt;margin-bottom:0pt;margin-left:2.25pt;margin-right:0pt;margin-top:0pt;text-align:left;">/s/ Mark A. Emalfarb</div>
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<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>ex_257726.htm
<DESCRIPTION>EXHIBIT 10.1
<TEXT>
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<p style="margin-bottom: 0px; text-align: right; margin-top: 0px"><font style="font-family: 'Times New Roman', Times, serif; font-size: 10pt"><b>Exhibit 10.1</b></font></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;"><b><u>COMPRAVENTA DE PARTICIPACIONES SOCIALES DE LA SOCIEDAD </u></b>&#8220;<b><u>BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L.</u></b>&#8221;<b><u>.</u></b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<u> </u></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">N&#218;MERO TRES MIL CUATROCIENTOS CATORCE.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En Madrid, a veintis&#233;is de julio de dos mil veintiuno.-----</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">ANTE M&#205;, IGNACIO MARTINEZ-GIL VICH, Notario de Madrid,</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">--------------------------- COMPARECEN: ------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">-----------------------------De una parte: -------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON PABLO GUTIERREZ G</b>&#211;<b>MEZ, </b>mayor de edad, de nacionalidad espa&#241;ola, ingeniero qu&#237;mico, con domicilio a estos efectos en 37005 Salamanca, calle Vel&#225;zquez n&#250;mero 4, 5&#186; A. Con D.N.I. y N.I.F. n&#250;mero 70.868.817-K, vigente, que me exhibe.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON ADRIAN PEREZ-CISTUE ARAUJO, </b>mayor de edad, de nacionalidad espa&#241;ola, con domicilio a estos efectos en 28034 Madrid, la calle Plaza Tubilla n&#250;mero 8, 1B. Con D.N.I. y N.I.F. n&#250;mero 51.490.865-Y, vigente que me exhibe.--</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON JOSE PELLICER ESPA</b>&#209;<b>A</b>, mayor de edad, de nacionalidad espa&#241;ola, empleado, con domicilio a estos efectos en Calle Santiago Bernab&#233;u, n&#250;mero 16, 6&#186; Izquierda, 28036 Madrid, provisto de D.N.I y N.I.F. n&#250;mero 677.191-W, vigente que me exhibe.------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON ADRI</b>&#193;<b>N MACHO CURIEL, </b>mayor de edad, de nacionalidad espa&#241;ola, soltero, analista de inversiones, con domicilio a estos efectos en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Con D.N.I. y N.I.F. n&#250;mero 05.940.065-Q, vigente que me exhibe.--------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON RICARDO ARJONA ANTOL</b>&#205;<b>N</b>, mayor de edad, (nacido el 19 de mayo de 1.967) de nacionalidad espa&#241;ola, empresario, casado en r&#233;gimen de separaci&#243;n de bienes de conformidad con lo establecido en el art&#237;culo 1334 del Codigo Civil, vecino de 41005 Sevilla, con domicilio en la calle Villegas y Marmolejo n&#250;mero 7, 6&#186; A, con D.N.I. y N.I.F. n&#250;mero 28.885.881-C.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Y<b> DON PETER KHAYAT, </b>mayor de edad,<b> </b>de nacionalidad libanesa, soltero, consultor financiero, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Provisto de Tarjeta de Residencia y N.I.E. n&#250;mero Y5629675W, vigente que me exhibe.----------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Y de otra parte:<b> DON EMILIO PRIETO BEDOYA, </b>mayor de edad, de nacionalidad espa&#241;ola, soltero, con domicilio a estos efectos en el Paseo de la Castellana n&#250;mero 259 Cm 28046 Madrid. Con D.N.I. y N.i.F. n&#250;mero 72.034.312-Z, vigente que me exhibe.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">----------------------- INTERVIENEN:------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1.- Don Pablo Gutierrez G&#243;mez, en nombre y representaci&#243;n como apoderado de: ---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a).- Los c&#243;nyuges <b>DON LUIS HILARIO GUERRA TRUEBA</b>, empleado de banca y <b>DO</b>&#209;<b>A PATRICIA CAROLINA CANTALAPIEDRA PUENTES, </b>aut&#243;noma, ambos mayores de edad, casados bajo el r&#233;gimen de gananciales, vecinos de Valladolid, con domicilio a estos efectos en la calle Alemania n&#250;mero 2, 3&#186; dcha., con D.N.I. y N.I.F. n&#250;meros 12.397.729-Q y 12.373.756 D, respectivamente, vigentes.-------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta, del poder especial a su favor conferido por medio de la escritura otorgada el d&#237;a 24 de junio de 2021, ante el Notario de Valladolid, Don Javier G&#243;mez Mart&#237;nez, con el n&#250;mero 3.807 de su protocolo.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha sido exhibida copia autorizada electronica de la escritura rese&#241;ada.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para la autorizaci&#243;n de la presente acta.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago constar expresamente que he cumplido con la obligaci&#243;n de identificaci&#243;n del titular real que impone la Ley 10/2010, de 28 de abril. A tales efectos, el citado representante manifiesta que sus representados son los &#250;nicos titulares reales de todas las declaraciones, actos, contratos y negocios jur&#237;dicos que contiene el presente instrumento p&#250;blico.------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b).- <b>DON JORGE HERN</b>&#193;<b>NDEZ ESTEBAN</b>, mayor de edad, de nacionalidad espa&#241;ola, soltero, ingeniero de telecomunicaciones, con domicilio en Calle Secundino Zuazo, n&#250;mero 17, 8&#186;A, 28055 Madrid, provisto de D.N.I. 2.640.923-V, en vigor.&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder otorgado en virtud de escritura p&#250;blica de fecha 23 de junio de 2021, ante el Notario de Madrid, Don Jos&#233; Luis Mart&#237;nez-Gil Vich, con el n&#250;mero 2.136 de su protocolo.--------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha sido exhibida copia autorizada electronica de la escritura rese&#241;ada.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago constar expresamente que he cumplido con la obligaci&#243;n de identificaci&#243;n del titular real que impone la Ley 10/2010, de 28 de abril. A tales efectos, el citado representante manifiesta que su representado es el &#250;nico titular real de todas las declaraciones, actos, contratos y negocios jur&#237;dicos que contiene el presente instrumento p&#250;blico.-----------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">c).- Los c&#243;nyuges: <b>DON YAHIA EL-AMRANI BENTAHAR, </b>ingeniero de telecomunicaciones y <b>DO</b>&#209;<b>A MUNA AOUFI DAOUD,</b> m&#233;dico, ambos mayores de edad, de nacionalidad espa&#241;ola, casado en r&#233;gimen legal marroqu&#237;, ingeniero de telecomunicaciones, con domicilio en Calle Secundino Zuazo, n&#250;mero 17, 8&#186;A, 28055 Madrid. Con D.N.I. y N.I.F. n&#250;meros 72.006.419-C y 54.348.284-C, respectivamente, vigentes.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder otorgado en virtud de escritura p&#250;blica de fecha 2 de julio de 2021, ante el Notario de Madrid, Don Jos&#233; Luis Mart&#237;nez-Gil Vich, con el n&#250;mero 2.246 de su protocolo.-------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha sido exhibida copia autorizada electr&#243;nica de la escritura rese&#241;ada.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago constar expresamente que he cumplido con la obligaci&#243;n de identificaci&#243;n del titular real que impone la Ley 10/2010, de 28 de abril. A tales efectos, el citado representante manifiesta que sus representados son los &#250;nicos titulares reales de todas las declaraciones, actos, contratos y negocios jur&#237;dicos que contiene el presente instrumento p&#250;blico.------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2.- Don Adrian Perez-Cistue Araujo en nombre y representaci&#243;n como apoderado de: ---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a).- <b>DON EMILIO GUTI</b>&#201;<b>RREZ G</b>&#211;<b>MEZ</b>, mayor de edad, de nacionalidad espa&#241;ola, casado en r&#233;gimen de separaci&#243;n de bienes ingeniero t&#233;cnico inform&#225;tico, vecino de Valladolid, con domicilio a estos efectos en la calle Santiago Alba n&#250;mero 3, 2&#186; D. Con D.N.I. y N.I.F. n&#250;mero 70.882.858-D.-----------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder especial a su favor conferido por medio de la escritura otorgada el d&#237;a 21 de julio de 2.021, ante el Notario de Valladolid, Don Javier G&#243;mez Mart&#237;nez, con el n&#250;mero 4.301 de orden de protocolo.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.-Que me ha sido exhibida copia autorizada electr&#243;nica de la escritura rese&#241;ada.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago constar expresamente que he cumplido con la obligaci&#243;n de identificaci&#243;n del titular real que impone la Ley 10/2010, de 28 de abril. A tales efectos, el citado representante manifiesta que su representado es el &#250;nico titular real de todas las declaraciones, actos, contratos y negocios jur&#237;dicos que contiene el presente instrumento p&#250;blico.-----------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b).- De la compa&#241;&#237;a de nacionalidad espa&#241;ola denominada &#8220;<b>CREUX AN</b>&#193;<b>LISIS ESTRAT</b>&#201;<b>GICOS, S.L.</b>&#8221;,<b> </b>con C.I.F. n&#250;mero B-37509817, domiciliada en Salamanca, calle Vel&#225;zquez 4, 5&#186; A, constituida por tiempo indefinido en virtud de escritura autorizada por el Notario de Madrid, Don Manuel de Cueto Garc&#237;a, el d&#237;a 29 de agosto de 2011, con el n&#250;mero 1835 de orden de protocolo, e inscrita en el Registro Mercantil de Salamanca en el tomo 420, folio 191, hoja n&#250;mero SA-13991, inscripci&#243;n 1&#170;.---</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La actividad principal de la sociedad, seg&#250;n manifiesta su compareciente, es la prestaci&#243;n de servicios, actividades de gesti&#243;n y administraci&#243;n, servicios educativos, sanitarios de ocio y entretenimiento, inform&#225;tica, telecomunicaciones y ofim&#225;tica, energ&#237;as alternativas, investigaci&#243;n, desarrollo e innovaci&#243;n, actividades cient&#237;ficas y t&#233;cnicas.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder especial a su favor conferido por el administrador &#218;nico de la sociedad Don Emilio Gutierrez Gomez, por medio de la escritura otorgada el d&#237;a 21 de julio de 2.021, ante el Notario de Valladolid, Don Javier G&#243;mez Mart&#237;nez, con el n&#250;mero 4.300 de orden de protocolo.-----------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha sido exhibida copia autorizada electr&#243;nica de la escritura rese&#241;ada.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago contar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio del acta de manifestaciones autorizada el d&#237;a 9 de abril de 2.012, ante el Notario de Madrid don Pedro Contreras Ranera, con el n&#250;mero 397 de orden de protocolo, y manifiesta que todo lo indicado en la misma no ha sufrido variaci&#243;n. Consulta la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.---------------------------------------------------------------------------------</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3.- Don Ricardo Arjona Antol&#237;n, en sus propios nombre y derecho.&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">4.- Don Jose Pellicer Espa&#241;a en nombre y representaci&#243;n de la sociedad &#8220;<b>FLOEMA BIOTEC, S.L.</b>&#8221;, con C.I.F. n&#250;mero B-86643749, domiciliada en Madrid, calle Padilla 40, 4&#186; Centro, constituida por tiempo indefinido en virtud de escritura autorizada por el Notario de Madrid, Don &#193;ngel Ben&#237;tez-Donoso Cuesta, el d&#237;a 24 de enero de 2013, con el n&#250;mero 56 de orden de protocolo, e inscrita en el Registro Mercantil de Madrid en el tomo 30887, folio 1, secci&#243;n 8&#170;, hoja n&#250;mero M-555914, inscripci&#243;n 1&#170;.-----</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La actividad principal de la sociedad, seg&#250;n manifiesta su representante, es la prestaci&#243;n de servicios, actividades de gesti&#243;n y administraci&#243;n; servicios educativos, sanitarios, de ocio y de administraci&#243;n; inform&#225;tica, telecomunicaciones y ofim&#225;tica; energ&#237;as alternativas; investigaci&#243;n, desarrollo e innovaci&#243;n; y de las actividades cient&#237;ficas y t&#233;cnicas. ------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta de la escritura p&#250;blica de fecha 22 de junio de 2021 autorizada ante el Notario de Madrid D. Eduardo Hijas Cid, bajo el n&#250;mero 648 de su protocolo.--------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha sido exhibida la copia autorizada de la escritura rese&#241;ada.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad del poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago contar que a mi juicio, las facultades representativas acreditadas son suficientes para el otorgamiento de la presente escritura. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario, hago contar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio del acta de manifestaciones autorizada por el Notario de Madrid Don Eduardo Hijas Cid, el d&#237;a 22 de junio de 2.021, con el n&#250;mero 647 de orden de protocolo, y manifiesta que todo lo indicado en la misma no ha sufrido variaci&#243;n. Consulta la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">5- Don Adri&#225;n Macho Curiel, en nombre y representaci&#243;n como apoderado<b>, </b>de la compa&#241;&#237;a de nacionalidad espa&#241;ola denominada &#8220;<b>INVEREADY BIOTECH III, S.C.R., S.A.</b>&#8221;, con C.I.F. n&#250;mero A-88139399, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituida con una duraci&#243;n de diez a&#241;os por medio de la escritura otorgada el d&#237;a 8 de junio de 2.018, ante el Notario de Barcelona Don Jaime Agustin Justribo, con el n&#250;mero 2.253 de orden de protocolo; inscrita en el Registro Mercantil de San Sebasti&#225;n, en el tomo 2.961, folio 169, secci&#243;n 8&#170;, hoja n&#250;mero SS-43.025, inscripci&#243;n 1&#170; y en el Registro Especial de Sociedades de Capital Riesgo en la Comisi&#243;n Nacional del Mercado de Valores.&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">El objeto social de la sociedad, seg&#250;n manifiesta su representante es el propio de una sociedad de capital riesgo.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder a su favor conferido por acuerdo adoptado por el Consejo de Administraci&#243;n de la sociedad en su reuni&#243;n celebrada el d&#237;a 17 de julio de 2.021, elevado a p&#250;blico por medio de la escritura otorgada el d&#237;a 22 de julio de 2.021, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.548 de orden de protocolo.----------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.-Que me ha sido exhibida la copia autorizada de la escritura rese&#241;ada.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 8 de junio de 2.018, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.254 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">6.- Don Peter Khayat,<b> </b>&nbsp;en nombre y representaci&#243;n como apoderada<b>, </b>de la compa&#241;&#237;a de nacionalidad espa&#241;ola denominada &#8220;<b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A.</b>&#8221;, A-88264130, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituida con una duraci&#243;n de diez a&#241;os por medio de la escritura otorgada el d&#237;a 12 de noviembre de 2.018, ante el Notario de Barcelona Don Jaime Agustin Justrib&#243;, con el n&#250;mero 2.427 de orden de protocolo; inscrita en el Registro Mercantil de San Sebasti&#225;n, en el tomo 2.963, folio 1, secci&#243;n 8&#170;, hoja n&#250;mero Ss-43-031, inscripci&#243;n 1&#170;.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">El objeto social de la sociedad, seg&#250;n manifiesta su representante es el propio de una sociedad de capital riesgo.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder a su favor conferido por el Consejo de Administraci&#243;n de la sociedad en su reuni&#243;n celebrada el d&#237;a 17 de julio de 2.021, elevado a p&#250;blico por medio de la escritura otorgada el d&#237;a 22 de julio de 2.021, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.549 de orden de protocolo.--------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.-Que me ha sido exhibida la copia autorizada de la escritura rese&#241;ada.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 12 de noviembre de 2.018, por el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 2.428 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">7.- Don Emilio Prieto Bedoya, en nombre y representaci&#243;n, como apoderado de la sociedad &#8220;<b>DYADIC INTERNATIONAL (USA), INC</b>&#8221;, con n&#250;mero de identificaci&#243;n (EIN) 65-0645993, domiciliada en 140 Intracoastal Pointe Drive, Suite 404, Jupiter, Florida 33477, USA, debidamente constituida de conformidad con las leyes del Estado de Florida y provista de C.I.F. espa&#241;ol n&#250;mero N4008645F.-------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La actividad principal de la sociedad, seg&#250;n manifiesta su representante, es el desarrollo de actividades de biotecnolog&#237;a.--------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder especial a su favor conferido por Don Mark Emalfarb, como representante de la sociedad, el d&#237;a 6 de julio de 2021, ante el Notario de la ciudad de Florida, estados Unidos, Don Palm Beach County, Florida, Don Heidi Zosiak, cuya copia debidamente apostillada tengo a la vista. --</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con este apoderamiento, yo, el Notario hago constar:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha exhibido el referido poder, que se encuentra redactado en idioma ingl&#233;s, idioma que en lo pertinente conozco.------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad del poderdante.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Yo, el Notario, hago contar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para la autorizaci&#243;n de la presente acta.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 30 de junio de 2.017, ante el Notario de Madrid Don Ignacio Mart&#237;nez-Gil Vich, con el n&#250;mero 986 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Tienen, a mi juicio, los comparecientes, seg&#250;n intervienen, la capacidad legal suficiente para formalizar la presente escritura de <b>COMPRAVENTA DE PARTICIPACIONES </b>y, al efecto,---------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">-------------------------------- EXPONEN<b>:</b> -------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I.- Que la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, es titular en pleno dominio y por el t&#237;tulo que se dir&#225; de diez millones setecientas siete mil setecientas cincuenta (10.707.750) participaciones, n&#250;meros 49.985.001 al 60.692.750, ambos inclusive de un (0,01) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L.&#8221;, con CIF n&#250;mero B-47729934; domiciliada en Valladolid, avenida de Francisco Vall&#233;s n&#250;mero 8; constituida por tiempo indefinido, mediante la escritura autorizada el d&#237;a 22 de septiembre de 2.014, por el Notario de Madrid Don Jorge Prades L&#243;pez, con el n&#250;mero 789 de orden de protocolo, inscrita en el Registro mercantil de Valladolid al tomo 1.477, folio 91, hoja n&#250;mero VA-27.242.&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su <u>objeto social</u> es el propio de una sociedad holding.---</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">TITULO.- Le pertenecen las referidas participaciones sociales por Escritura de Ampliaci&#243;n de Capital de fecha 30 de junio de 2017, otorgada ante el Notario de Madrid, D. Jose Luis Martinez Gil Vich, bajo el n&#250;mero de protocolo 1.814.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La presente transmisi&#243;n ha sido autorizada por la Junta General Extraordinaria y Universal de Socios celebrada en fecha 26 de julio de 2021, seg&#250;n resulta de la certificaci&#243;n que me exhibe, expedida el d&#237;a 26 de julio de 2021, por el Secretario no Consejero del Consejo de Administraci&#243;n de la sociedad, D. Borja D&#237;az-Guerra Heredero, con el visto bueno de su Presidente, D. Ricardo Arjona Antol&#237;n.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">CARGAS.- Manifiesta el representante de la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, que las referidas participaciones de su titularidad est&#225;n libres de cargas y grav&#225;menes.-----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">II. Que los comparecientes, en la presente fecha han otorgado ante m&#237; un acta de dep&#243;sito notarial bajo el n&#250;mero de protocolo &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;en virtud de la cual me han requerido para que libere el precio correspondiente a la presente compraventa con car&#225;cter inmediatamente posterior a su otorgamiento.----------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">III.- Que los comparecientes, seg&#250;n intervienen, tienen convenida la compraventa de las referidas participaciones, que se llevan a efecto por esta escritura, con arreglo a las siguientes,-------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">--------------------------- ESTIPULACIONES:--------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">PRIMERA.- La sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, por medio de su representante en este acto, <u>VENDE Y TRANSMITE</u> a CREUX AN&#193;LISIS ESTRAT&#201;GICOS, S.L., DON EMILIO GUTI&#201;RREZ G&#211;MEZ, DON RICARDO ARJONA ANTOL&#205;N, DON LUIS HILARIO GUERRA TRUEBA, FLOEMA BIOTEC, S.L., DON JORGE HERN&#193;NDEZ ESTEBAN, DON YAHIA EL-AMRANI, INVEREADY BIOTECH III, S.C.R., S.A. y INVEREADY BIOTECH III PARALLEL, S.C.R., S.A., que COMPRAN Y ADQUIEREN, (10.707.750) participaciones, n&#250;meros 49.985.001 al 60.692.750, ambos inclusive de un (0,01) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L.&#8221;, totalmente desembolsadas, con cuanto a las mismas sea accesorio e inherente, y libres de toda carga, gravamen, trabas, embargos y pignoraciones conforme a continuaci&#243;n se indica:---------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON YAHIA EL-AMRANI</b>, ADQUIERE 171.908 participaciones sociales, numeradas de la 49.985.001 a 50.156.908, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de &nbsp;&nbsp;&nbsp;<b>VEINTE MIL EUROS</b> (<b>20.000,00 Euros)</b>.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON JORGE HERN</b>&#193;<b>NDEZ ESTEBAN, </b>ADQUIERE 362.726 participaciones sociales, numeradas de la 50.156.909 a la 50.519.634, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>CUARENTA Y DOS MIL DOSCIENTOS EUROS (42.200 </b>&#8364;<b>)</b>.--------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La sociedad <b>FLOEMA BIOTEC, S.L.</b>, ADQUIERE 156.436 participaciones sociales, numeradas de la 50.519.635 a la 50.676.070, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>DIECIOCHO MIL DOSCIENTOS EUROS</b> (<b>18.200,00 </b>&#8364;<b>)</b>.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON LUIS HILARIO GUERRA TRUEBA</b>, ADQUIERE 171.908 participaciones sociales, numeradas de la 50.676.071 a la 50.047.978, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total <b>VEINTE MIL EUROS (20.000,00 </b>&#8364;<b>).--------------------------------------------------------------------------------- </b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON EMILIO GUTI</b>&#201;<b>RREZ G</b>&#211;<b>MEZ</b>, ADQUIERE 61.887 participaciones sociales, numeradas de la 50.847.979 a la 50.909.865, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>SIETE MIL DOSCIENTOS EUROS</b> (<b>7.200,00 </b>&#8364;<b>)</b>.----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON RICARDO ARJONA ANTOL</b>&#205;<b>N</b>, ADQUIERE 362.726 participaciones sociales, numeradas de la 50.909.866 a la 51.272.591, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>CUARENTA Y DOS MIL DOSCIENTOS EUROS</b> <b>(42.200,00 </b>&#8364;<b>)</b>.---------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La sociedad <b>CREUX AN</b>&#193;<b>LISIS ESTRAT</b>&#201;<b>GICOS, S.L.</b>, ADQUIERE 362.726 participaciones sociales, numeradas de la 51.272.592 a la 51.635.317, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>CUARENTA Y DOS MIL DOSCIENTOS EUROS</b> <b>(42.200,00 </b>&#8364;<b>)</b>.-------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>INVEREADY BIOTECH III, S.C.R., S.A.</b>, ADQUIERE 7.547.861 participaciones sociales, numeradas de la 51.635.318 a la 59.183.178, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>OCHOCIENTOS SETENTA Y OCHO MIL CIENTO VEINTISIETE EUROS CON NOVENTA Y NUEVE CENTIMOS (878.127,99 </b>&#8364;<b>)</b>.------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A.</b> ADQUIERE 1.509.572 participaciones sociales, numeradas de la 59.183.179 a la 60.692.750, ambas inclusive, titularidad de Dyadic International (USA), Inc., por un precio total de <b>CIENTO SETENTA Y CINCO MIL SEISCIENTOS VEINTICINCO EUROS CON SESENTA C</b>&#201;<b>NTIMOS (175.625,57 </b>&#8364;<b>)</b>.------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SEGUNDA.- El precio de la compraventa es en conjunto de <b>UN MILLON DOSCIENTOS CUARENTA Y CINCO MIL SETECIENTOS CINCUENTA Y TRES MIL EUROS CON CINCUENTA Y SEIS CENTIMOS (1.245.753,56 </b>&#8364;<b>)</b>.&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">TERCERA.- Yo, el Notario, una vez otorgada la presente Escritura realizar&#233; el pago del precio total de la compraventa a la parte vendedora mediante transferencia bancaria a la cuenta n&#250;mero SWIFT SNTRUS3AXXX n&#250;mero 1000090561274, titularidad de la parte vendedora, todo ello en los t&#233;rminos y condiciones previstos en el acta de dep&#243;sito notarial otorgada en la presente fecha por m&#237; bajo el n&#250;mero de protocolo &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;en virtud de la cual acept&#233; el requerimiento de las partes compradoras y la parte vendedora de liberar los fondos correspondientes a la presente compraventa de participaciones.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Una vez realizada la transferencia, dejar&#233; incorporada a la presente escritura copia de dicha transferencia.---------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">CUARTA.-<b> </b>En este acto queda diligenciado un impreso modelo D-1B, correspondiente a la declaraci&#243;n de la liquidaci&#243;n de la inversi&#243;n extranjera realizada por la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, dejando unido a esta matriz dicho impreso debidamente cumplimentado y presentado en el registro correspondiente.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">QUINTA.- Los gastos que se deriven de esta escritura ser&#225;n a cargo del comprador.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SEXTA.-<b> </b>Manifiestan los comparecientes que comunicar&#225;n la presente transmisi&#243;n al &#243;rgano de administraci&#243;n de la sociedad, con el fin de quedar esta anotada en el Libro Registro de Socios, tal como prev&#233; la Ley de Sociedades de Capital.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">S&#201;PTIMA.- La transmisi&#243;n que se realiza por medio de esta escritura est&#225; exenta del pago del Impuesto de Transmisiones Patrimoniales y actos Jur&#237;dicos Documentados (Art.314 RDL 4/2015 de 23 de octubre de 2.015, por el que se aprueba el Texto Refundido de la Ley del Mercado de Valores).-------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><u>PROTECCI</u>&#211;<u>N DE DATOS DE CAR</u>&#193;<u>CTER PERSONAL:</u>--</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">De conformidad con lo previsto en el Reglamento General de Protecci&#243;n de Datos europeo, se informa de que los datos personales de los intervinientes ser&#225;n tratados por el Notario autorizante, cuyos datos de contacto figuran en el presente documento. Los datos ser&#225;n tratados con la finalidad de realizar las funciones propias de la actividad notarial y para la facturaci&#243;n y gesti&#243;n de clientes, para lo cual se conservar&#225;n durante los plazos previstos en la normativa aplicable y, en cualquier caso, mientras se mantenga la relaci&#243;n con los interesados. ------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La base del tratamiento es el desempe&#241;o de las funciones p&#250;blicas notariales, lo que obliga a que los datos sean facilitados al Notario e impedir&#237;a su intervenci&#243;n en caso contrario. Se realizar&#225;n las comunicaciones previstas en la Ley a las Administraciones P&#250;blicas y, en su caso, al Notario que suceda al actual en la plaza.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Los intervinientes tienen derecho a solicitar el acceso a sus datos personales, su rectificaci&#243;n, su supresi&#243;n, su portabilidad y la limitaci&#243;n de su tratamiento, as&#237; como oponerse a este. Frente a cualquier eventual vulneraci&#243;n de derechos, puede presentarse una reclamaci&#243;n ante la Agencia Espa&#241;ola de Protecci&#243;n de Datos. Si se facilitan datos de personas distintas de los intervinientes, estos deber&#225;n haberles informado previamente de todo lo previsto en el art&#237;culo 14 del RGPD.-------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">As&#237; lo dicen y otorgan los comparecientes, a quienes hago las reservas y advertencias legales, en especial y a efectos fiscales advierto de las obligaciones y responsabilidades tributarias que incumben a las partes en su aspecto material, formal y sancionador, y de las consecuencias de toda &#237;ndole que se derivar&#237;an de la inexactitud de sus declaraciones.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Doy cumplimiento al requisito de la lectura en la forma prevenida por el art&#237;culo 193 del Reglamento Notarial; tras la lectura, doy fe de que los comparecientes manifiestan haber quedado informados del contenido del instrumento p&#250;blico y prestar su libre consentimiento a este contenido, firmando conmigo Notario.---</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, Notario, DOY FE:----------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a) De haber identificado a los comparecientes por medio de sus documentos de identidad, rese&#241;ados en la comparecencia, que me han sido exhibidos.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b) De que los comparecientes, <u>a mi juicio</u>, tienen capacidad y est&#225;n legitimados para el presente otorgamiento.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">c) De que el consentimiento de los otorgantes ha sido libremente prestado.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">d) De que el otorgamiento se adecua a la legalidad y a la voluntad libre y debidamente informada de los comparecientes.-------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">e) De que el presente instrumento p&#250;blico queda extendido en trece folios de papel de uso exclusivo para documentos notariales, serie GA, n&#250;meros el presente y los doce anteriores en orden correlativo, que signo, firmo y rubrico, de cuya adecuaci&#243;n y completo contenido doy fe.-</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b><u>SALE AND PURCHASE OF SHARES OF THE COMPANY "BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L.".-------------------------- </u></b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">NUMBER THREE THOUSAND FOUR HUNDRED AND FOURTEEN.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In Madrid, on the twenty-sixth day of July of the year two thousand and twenty-one.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">BEFORE ME, IGNACIO MARTINEZ-GIL VICH, Notary Public of Madrid,&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">--------------------------- APPEAR: -------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">-----------------------------From one party: ---------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON PABLO GUTIERREZ G</b>&#211;<b>MEZ</b>, of legal age, of Spanish nationality, chemical engineer, with address for these purposes at 37005 Salamanca, calle Vel&#225;zquez number 4, 5&#186; A. With D.N.I. and N.I.F. number 70.868.817-K, in force, which he exhibits to me.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. ADRIAN PEREZ-CISTUE ARAUJO</b>, of legal age, of Spanish nationality, with address for these purposes in 28034 Madrid, at Calle Plaza Tubilla number 8, 1B. With D.N.I. and N.I.F. number 51.490.865-Y, in force and exhibited to me.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. JOSE PELLICER ESPA</b>&#209;<b>A</b>, of legal age, of Spanish nationality, employee, with address for these purposes at Calle Santiago Bernab&#233;u, number 16, 6&#186; Izquierda, 28036 Madrid, with D.N.I. and N.I.F. number 677.191-W, in force, which he exhibits to me.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. ADRI</b>&#193;<b>N MACHO CURIEL</b>, of legal age, Spanish nationality, single, investment analyst, with address for these purposes at Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa). With D.N.I. and N.I.F. number 05.940.065-Q, in force and exhibited to me.------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. RICARDO ARJONA ANTOL</b>&#205;<b>N</b>, of legal age, (born May 19, 1967) of Spanish nationality, businessman, married in regime of separation of goods in accordance with the established in article 1334 of the Civil Code, neighbor of 41005 Seville, with domicile in Villegas y Marmolejo street number 7, 6&#186; A, with D.N.I. and N.I.F. number 28.885.881-C.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">And <b>Mr. PETER KHAYAT</b>, of legal age, Lebanese nationality, single, financial consultant, with address at Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Provided with Residence Card and N.I.E. number Y5629675W, in force, which he exhibits to me.--------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">And on the other hand: <b>Mr. EMILIO PRIETO BEDOYA</b>, of legal age, of Spanish nationality, single, with address for these purposes at Paseo de la Castellana number 259 Cm 28046 Madrid. With D.N.I. and N.i.F. number 72.034.312-Z, in force and exhibited to me.----------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">----------------------- INTERVENE:-------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1.- Mr. Pablo Gutierrez G&#243;mez, on behalf of and representing as attorney-in-fact: ---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a).- The spouses <b>DON LUIS HILARIO GUERRA TRUEBA</b>, bank employee and <b>DO</b>&#209;<b>A PATRICIA CAROLINA CANTALAPIEDRA PUENTES</b>, self-employed, both of legal age, married under the community property regime, neighbors of Valladolid, with domicile for these purposes at Alemania Street number 2, 3&#186; dcha., with D.N.I. and N.I.F. numbers 12.397.729-Q and 12.373.756 D, respectively, in force.---------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Their legitimacy for this act results from the special power of attorney in their favor conferred by means of the deed granted on June 24, 2021, before the Notary Public of Valladolid, Mr. Javier G&#243;mez Mart&#237;nez, with number 3,807 of his protocol.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this power of attorney, I, the Notary Public, hereby state the following:---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That an authorized electronic copy of the above-mentioned deed has been exhibited to me.------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, that the capacity of the attorney-in-fact has not changed.-----------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186; - I, the Notary, state for the record that in my opinion, the representative powers accredited are sufficient for the authorization of these minutes.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, expressly state for the record that I have complied with the obligation of identification of the beneficial owner imposed by Law 10/2010, of April 28th. To such effects, the aforementioned representative declares that his represented parties are the only real titleholders of all the declarations, acts, contracts and legal business contained in this public instrument.---------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b) - <b>Mr. JORGE HERN</b>&#193;<b>NDEZ ESTEBAN</b>, of legal age, Spanish nationality, single, telecommunications engineer, with address at Calle Secundino Zuazo, number 17, 8&#186;A, 28055 Madrid, holder of valid D.N.I. 2.640.923-V, in force.-----</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">His legitimacy for this act results from the power of attorney granted by virtue of public deed dated June 23, 2021, before the Notary Public of Madrid, Mr. Jos&#233; Luis Mart&#237;nez-Gil Vich, under number 2,136 of his protocol.---------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this power of attorney, I, the Notary Public, hereby state the following:---------------------------------------------------------------------------------</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That an authorized electronic copy of the above-mentioned deed has been exhibited to me.------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, that the capacity of the attorney-in-fact has not changed.----------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, expressly state that I have complied with the obligation of identification of the beneficial owner imposed by Law 10/2010, of April 28th. To such effects, the aforementioned representative declares that the represented party is the sole beneficial owner of all the declarations, acts, contracts and legal business contained in this public instrument.------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">c) - The spouses: <b>Mr. YAHIA EL-AMRANI BENTAHAR</b>, telecommunications engineer and <b>Mrs. MUNA AOUFI DAOUD</b>, doctor, both of legal age, of Spanish nationality, married under Moroccan law, telecommunications engineer, residing at Calle Secundino Zuazo, number 17, 8&#186;A, 28055 Madrid. With valid D.N.I. and N.I.F. numbers 72.006.419-C and 54.348.284-C, respectively.---------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Their legitimacy for this act results from the power of attorney granted by virtue of public deed dated July 2, 2021, before the Notary Public of Madrid, Mr. Jos&#233; Luis Mart&#237;nez-Gil Vich, under number 2,246 of his protocol.----------------------</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this power of attorney, I, the Notary Public, hereby state the following:---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That an authorized electronic copy of the above-mentioned deed has been exhibited to me.------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, expressly state for the record that I have complied with the obligation of identification of the beneficial owner imposed by Law 10/2010, of April 28th. To such effects, the aforementioned representative declares that his principals are the sole beneficial owners of all the declarations, acts, contracts and legal transactions contained in this public instrument.---------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2.- Mr. Adrian Perez-Cistue Araujo in the name and representation as attorney-in-fact of: ------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a).- <b>Mr. EMILIO GUTI</b>&#201;<b>RREZ G</b>&#211;<b>MEZ</b>, of legal age, of Spanish nationality, married in separation of property regime computer technical engineer, resident of Valladolid, with domicile for these purposes in Santiago Alba Street number 3, 2&#186; D. With D.N.I. and N.I.F. number 70.882.858-D.---------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">His legitimacy for this act results from the special power of attorney in his favor conferred by means of the deed granted on July 21, 2.021, before the Notary Public of Valladolid, Mr. Javier G&#243;mez Mart&#237;nez, with the number 4.301 of the protocol order.&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this deed of power of attorney, I, the Notary Public, state the following:---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That an electronic authorized copy of the above-mentioned deed has been exhibited to me.------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, expressly state for the record that I have complied with the obligation of identification of the beneficial owner imposed by Law 10/2010, of April 28th. To such effects, the aforementioned representative declares that his representative is the sole beneficial owner of all the declarations, acts, contracts and legal business contained in this public instrument.---------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b) - Of the Spanish company "<b>CREUX AN</b>&#193;<b>LISIS AN</b>&#193;<b>LIS ESTRAT</b>&#201;<b>GICOS, S.L.</b>", with tax identification number B-37509817. number B-37509817, domiciled in Salamanca, calle Vel&#225;zquez 4, 5&#186; A, incorporated for an indefinite period of time by virtue of a deed authorized by the Notary Public of Madrid, Mr. Manuel de Cueto Garc&#237;a, on August 29, 2011, with protocol order number 1835, and registered in the Mercantile Registry of Salamanca in volume 420, folio 191, sheet number SA-13991, entry 1.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The main activity of the company, as stated by the person appearing, is the provision of services, management and administration activities, educational, health, leisure and entertainment services, information technology, telecommunications and office automation, alternative energies, research, development and innovation, scientific and technical activities. --------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its legitimacy for this act results from the special power of attorney in its favor conferred by the sole administrator of the company Mr. Emilio Gutierrez Gomez, by means of the deed granted on July 21, 2.021, before the Notary Public of Valladolid, Mr. Javier G&#243;mez Mart&#237;nez, with the number 4.300 of the protocol order.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That an authorized electronic copy of the aforementioned deed has been exhibited to me.-------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, hereby state that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of the deed of manifestations authorized on April 9, 2012, before the Notary Public of Madrid Mr. Pedro Contreras Ranera, under number 397 of the protocol order, and state that everything indicated therein has not undergone any variation. Consultation of the database of real ownership, I verify that the real owner coincides with the declared in the above mentioned deed.--------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3.- Mr. Ricardo Arjona Antol&#237;n, in his own name and right.&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">4.- Mr. Jose Pellicer Espa&#241;a on behalf and representation of the company "<b>FLOEMA BIOTEC, S.L</b>.", with C.I.F. number B-86643749. number B-86643749, domiciled in Madrid, calle Padilla 40, 4&#186; Centro, incorporated for an indefinite period of time by virtue of a deed authorized by the Notary Public of Madrid, Mr. &#193;ngel Ben&#237;tez-Donoso Cuesta, on January 24, 2013, with protocol order number 56, and registered in the Mercantile Registry of Madrid in volume 30887, folio 1, section 8&#170;, sheet number M-555914, entry 1&#170;.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The main activity of the company, according to its representative, is the provision of services, management and administration activities; educational, health, leisure and administration services; IT, telecommunications and office automation; alternative energies; research, development and innovation; and scientific and technical activities. ---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its legitimacy for this act results from the public deed dated June 22, 2021 authorized before the Notary Public of Madrid Mr. Eduardo Hijas Cid, under number 648 of his protocol.----------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That the authorized copy of the aforementioned deed has been exhibited to me.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, declare that in my opinion, the accredited representative powers are sufficient for the execution of this deed. ------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, hereby declare that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of the record of declarations authorized by the Notary of Madrid, Mr. Eduardo Hijas Cid, on June 22, 2.021, under number 647 of the protocol order, and declare that everything indicated therein has not undergone any variation. Consultation of the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.--------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">5- Mr. Adri&#225;n Macho Curiel, in name and representation as attorney-in-fact, of the Spanish company called "<b>INVEREADY BIOTECH III, S.C.R., S.A.", </b>with C.I.F. number A-88139399, with address in Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituted with a duration of ten years by means of the deed granted on June 8, 2.018, before the Notary of Barcelona Mr. Jaime Agustin Justribo, with the number 2. 253 of protocol order; registered in the Mercantile Registry of San Sebastian, in volume 2.961, folio 169, section 8&#170;, sheet number SS-43.025, inscription 1&#170; and in the Special Registry of Venture Capital Companies at the National Securities Market Commission (Comisi&#243;n Nacional del Mercado de Valores).&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The corporate purpose of the company, according to its representative, is that of a venture capital company.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its legitimacy for this act results from the power of attorney in its favor conferred by agreement adopted by the Board of Directors of the company at its meeting held on July 17, 2002, which was made public by means of the deed granted on July 22, 2002, before the Notary Public of Barcelona, Mr. Jaime Agust&#237;n Justrib&#243;, under number 1,548 of the protocol order.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this deed of power of attorney, I, the Notary, state the following:&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That the authorized copy of the above-mentioned deed has been exhibited to me.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the attorney-in-fact has not changed.--------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a deed of manifestations authorized on June 8, 2008, before the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 1,254 of the protocol order, stating that his representative has not modified the content of the same. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">6.- Mr. Peter Khayat, in name and representation as attorney-in-fact, of the Spanish company called "<b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A</b>.", A-88264130, with domicile in Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituted with a duration of ten years by means of the deed granted on November 12, 2. 018, before the Notary of Barcelona Mr. Jaime Agustin Justrib&#243;, with the number 2.427 of protocol order; registered in the Mercantile Registry of San Sebastian, in the volume 2.963, folio 1, section 8&#170;, sheet number Ss-43-031, inscription 1&#170;.---------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The corporate purpose of the company, according to its representative, is that of a venture capital company.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its legitimacy for this act results from the power of attorney in its favor conferred by the Board of Directors of the company in its meeting held on July 17, 2.021, elevated to public by means of the deed granted on July 22, 2.021, before the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 1.549 of the protocol order.&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In relation to this deed of power of attorney, I, the Notary, state the following:&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That the authorized copy of the above-mentioned deed has been exhibited to me.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the attorney-in-fact has not changed.--------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186; - I, the Notary Public, hereby state that in my opinion, the representative powers accredited are sufficient for the execution of this deed.----------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, hereby state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a record of declarations authorized on November 12, 2008, by the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 2,428 of the protocol order, and his representative declares that the content of the same has not been modified. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.---------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">7.- Mr. Emilio Prieto Bedoya, in the name and representation, as attorney-in-fact of the company "<b>DYADIC INTERNATIONAL (USA), INC</b>", with identification number (EIN) 65-0645993, domiciled at 140 Intracoastal Pointe Drive, Suite 404, Jupiter, Florida 33477, USA, duly constituted in accordance with the laws of the State of Florida and provided with Spanish C.I.F. number N4008645F.----------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The main activity of the company, according to its representative, is the development of biotechnology activities.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its legitimacy for this act results from the special power of attorney in its favor conferred by Mr. Mark Emalfarb, as representative of the company, on July 6, 2021, before the Notary of the city of Florida, United States, Mr. Palm Beach County, Florida, Mr. Heidi Zosiak, a duly apostilled copy of which I have before me. -------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In connection with this power of attorney, I, the Notary, hereby state:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- That he has exhibited to me the aforementioned power of attorney, which is written in English, a language with which I am familiar in all pertinent aspects.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.---------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- I, the Notary, state that in my opinion, the accredited representative powers are sufficient for the authorization of the present deed.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, the Notary, state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a deed of manifestations authorized on June 30, 2007, before the Notary Public of Madrid Mr. Ignacio Mart&#237;nez-Gil Vich, under number 986 of the protocol order, and his representative declares that the content of the same has not been modified. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in said deed.----------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In my opinion, the parties, as they intervene, have sufficient legal capacity to formalize the present deed of <b>PURCHASE AND SALE OF SHARES</b> and, to that effect,</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">-------------------------------- EXHIBIT: -------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I.- That the company "DYADIC INTERNATIONAL (USA), INC.", is the holder in full ownership and by the title to be stated of ten million seven hundred and seven thousand seven hundred and fifty (10,707,750) shares, numbers 49,985,001 to 60,692,750, both inclusive, of one (0.01) cent nominal value each of the company "BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L." with CIF number B-47729934; domiciled in Valladolid, Avenida de Francisco Vall&#233;s number 8; incorporated for an indefinite period of time, by means of a deed authorized on September 22, 2014, by the Notary Public of Madrid Mr. Jorge Prades L&#243;pez, with protocol number 789, registered in the Commercial Registry of Valladolid in volume 1,477, folio 91, page number VA-27,242.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Its corporate purpose is that of a holding company.-------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">TITLE: The aforementioned shares belong to the company by Deed of Capital Increase dated June 30, 2017, executed before the Notary Public of Madrid, Mr. Jose Luis Martinez Gil Vich, under protocol number 1,814.------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">This transfer has been authorized by the Extraordinary and Universal General Shareholders' Meeting held on July 26, 2021, as shown in the certification exhibited to me, issued on July 26, 2021, by the Non-Director Secretary of the Board of Directors of the Company, Mr. Borja D&#237;az-Guerra Heredero, with the approval of its Chairman, Mr. Ricardo Arjona Antol&#237;n.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">CHARGES: The representative of the company "DYADIC INTERNATIONAL (USA), INC", declares that the referred shares of its ownership are free of charges and encumbrances.-------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">II. That the parties hereto, on this date, have executed before me a notarial deed of deposit under protocol number by virtue of which they have requested me to release the price corresponding to the present sale and purchase immediately after its execution.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">III.- That the parties, as intervening, have agreed the purchase and sale of the referred shares, which are carried into effect by this deed, in accordance with the following,&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">--------------------------- PROVISIONS:--------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">FIRST.- The company "DYADIC INTERNATIONAL (USA), INC", through its representative in this act, SELLS AND TRANSFERS to CREUX AN&#193;LISIS AN&#193;LIS ESTRAT&#201;GICOS, S.L., EMILIO GUTI&#201;RREZ G&#211;MEZ, RICARDO ARJONA ANTOL&#205;N, LUIS HILARIO GUERRA TRUEBA, FLOEMA BIOTEC, S.L., JORGE HERN&#193;NDEZ ESTEBAN, YAHIA EL-AMRANI, INVEREADY BIOTECH III, S.C.R., S.A. and INVEREADY BIOTECH III PARALLEL, S.C.R., S.A., that PURCHASE AND ACQUIRE, (10,707,750) shares, numbers 49,985,001 to 60,692,750, both inclusive, of one (0.01) cents of nominal value each of the company "BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY, S.L.", fully paid up, with all that is accessory and inherent thereto, and free of all charges, encumbrances, encumbrances, liens and pledges as indicated below:------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>MR. YAHIA EL-AMRANI</b>, ACQUIRES 171,908 shares, numbered from 49,985,001 to 50,156,908, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>TWENTY THO THOUSAND EUROS (20,000.00 Euros).</b>--------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>MR. JORGE HERN</b>&#193;<b>NDEZ ESTEBAN,</b> ACQUIRES 362,726 shares, numbered from 50,156,909 to 50,519,634, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>FORTY TWO THO THOUSAND TWO HUNDRED EUROS (42,200 Euros).</b>---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The company <b>FLOEMA BIOTEC, S.L.,</b> ACQUIRES 156,436 shares, numbered from 50,519,635 to 50,676,070, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>EIGHTEEN THOUSAND TWO HUNDRED EUROS (18,200.00 </b>&#8364;<b>).</b>&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. LUIS HILARIO GUERRA TRUEBA,</b> ACQUIRES 171.908 shares, numbered from 50.676.071 to 50.047.978, both inclusive, owned by Dyadic International (USA), Inc. for a total price of TWENTY THO THOUSAND EUROS (20.000,00 &#8364;).</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. EMILIO GUTI</b>&#201;<b>RREZ G</b>&#211;<b>MEZ</b>, ACQUIRES 61.887 shares, numbered from 50.847.979 to 50.909.865, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>SEVEN THOUSAND TWO HUNDRED EUROS (7.200,00 </b>&#8364;<b>). </b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. RICARDO ARJONA ANTOL</b>&#205;<b>N</b>, ACQUIRES 362,726 shares, numbered from 50,909,866 to 51,272,591, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>FORTY TWO THO THOUSAND TWO HUNDRED EUROS (42,200.00 </b>&#8364;<b>).</b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>CREUX AN</b>&#193;<b>LISIS ESTRAT</b>&#201;<b>GICOS, S.L</b>., ACQUIRES 362,726 shares, numbered from 51,272,592 to 51,635,317, both inclusive, owned by Dyadic International (USA), Inc. for a total price <b>of FORTY TWO THO THOUSAND TWO HUNDRED EUROS (42,200.00 </b>&#8364;<b>).</b>---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>INVEREADY BIOTECH III, S.C.R., S.A</b>., ACQUIRES 7,547,861 shares, numbered from 51,635,318 to 59,183,178, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>EIGHT HUNDRED AND SEVENTY-EIGHT THOUSAND ONE HUNDRED AND TWENTY SEVEN EUROS AND NINETY-NINE CENTS (878,127.99 </b>&#8364;<b>).</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A.</b> ACQUIRES 1,509,572 shares, numbered from 59,183,179 to 60,692,750, both inclusive, owned by Dyadic International (USA), Inc. for a total price of <b>ONE HUNDRED SEVENTY-FIVE THOUSAND SIX HUNDRED TWENTY-FIVE EUROS AND SIXTY CENTS (175,625.57 </b>&#8364;<b>).</b>--</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SECOND.- The price of the sale and purchase is ONE MILLION TWO HUNDRED AND FORTY-FIVE THOUSAND SEVEN HUNDRED AND FIFTY-THREE THOUSAND EUROS AND FIFTY-SIX CENTS (1,245,753.56 &#8364;).----------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">THIRD.- I, the Notary, once this Deed has been executed, will make the payment of the total price of the sale and purchase to the selling party by means of a bank transfer to the SWIFT account number SNTRUS3AXXX number 1000090561274, owned by the selling party, all in accordance with the terms and conditions set forth in the notarial deposit deed executed on this date by me under the protocol number by virtue of which I accepted the request of the purchasing parties and the selling party to release the funds corresponding to this sale and purchase of shares.-----------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Once the transfer has been made, I will leave a copy of said transfer incorporated in this deed.--------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">FOURTH.- A form model D-1B is hereby executed, corresponding to the declaration of the liquidation of the foreign investment made by the company "DYADIC INTERNATIONAL (USA), INC", leaving attached to this deed said form duly completed and presented at the corresponding registry.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">FIFTH.- The expenses arising from this deed shall be borne by the purchaser.&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SIXTH.- The parties hereto declare that they will communicate the present transfer to the administrative body of the company, in order to be recorded in the Register of Shareholders, as provided for in the Capital Companies Act.---</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SEVENTH.- The transfer carried out by means of this deed is exempt from the payment of the Transfer Tax and Documented Legal Acts (Art.314 RDL 4/2015 of 23 October 2015, which approves the Consolidated Text of the Securities Market Law).&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">PROTECTION OF PERSONAL DATA:--------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In accordance with the provisions of the European General Data Protection Regulation, it is hereby informed that the personal data of the intervening parties will be processed by the authorizing Notary, whose contact details appear in this document. The data will be processed for the purpose of performing the functions inherent to the notarial activity and for billing and client management, for which purpose they will be kept for the periods provided for in the applicable regulations and, in any case, for as long as the relationship with the interested parties is maintained. ----------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">The basis of the processing is the performance of notarial public functions, which requires the data to be provided to the Notary and would otherwise prevent his intervention. The communications foreseen in the Law will be made to the Public Administrations and, if applicable, to the Notary who succeeds the current Notary in the position.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Participants have the right to request access to their personal data, its rectification, deletion, portability and limitation of its processing, as well as to oppose its processing. In the event of any violation of rights, a complaint may be lodged with the Spanish Data Protection Agency (Agencia Espa&#241;ola de Protecci&#243;n de Datos). If data of persons other than the participants are provided, they must have previously informed them of all the provisions of Article 14 of the GDPR.------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">This is so stated and granted by the parties, to whom I make the legal reservations and warnings, especially and for tax purposes I warn of the tax obligations and responsibilities incumbent on the parties in their material, formal and sanctioning aspect, and of the consequences of all kinds that would result from the inaccuracy of their declarations.----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I comply with the requirement of the reading in the manner provided for in Article 193 of the Notarial Regulations; after the reading, I attest that the participants declare that they have been informed of the content of the public instrument and give their free consent to this content, signing with me, Notary.-----------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I, Notary, WITNESS:-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a) That I have identified the parties by means of their identity documents, as stated in the appearance, which have been exhibited to me.-------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b) That the parties, in my opinion, have capacity and are legitimized for the present execution.--------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">c) That the consent of the grantors has been freely given.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">d) That the grant is in accordance with the legality and the free and duly informed will of the parties.----------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">e) That the present public instrument is drawn on thirteen sheets of paper of exclusive use for notarial documents, series GA, numbers the present and the twelve previous ones in correlative order, which I sign, sign and countersign, of whose adequacy and complete content I attest.</p>

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<DOCUMENT>
<TYPE>EX-10.2
<SEQUENCE>3
<FILENAME>ex_267318.htm
<DESCRIPTION>EXHIBIT 10.2
<TEXT>
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<p style="margin-bottom: 0px; text-align: right; margin-top: 0px"><font style="font-family: 'Times New Roman', Times, serif; font-size: 10pt"><b>Exhibit 10.2</b></font></p>

<p style="margin-bottom: 0px; text-align: left; margin-top: 0px"><font style="font-family: 'Times New Roman', Times, serif; font-size: 10pt">&nbsp;</font></p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;"><b><u>COMPRAVENTA DE PARTICIPACIONES SOCIALES DE LA SOCIEDAD </u></b>&#8220;<b><u>VLP THE VACCINES COMPANY, S.L.</u></b>&#8221;<b><u>.</u></b><u>------------------------------------------ </u></p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">N&#218;MERO TRES MIL CUATROCIENTOS QUINCE.-----------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En Madrid, a veintis&#233;is de julio de dos mil veintiuno.-----</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">ANTE M&#205;,&nbsp; IGNACIO MARTINEZ-GIL VICH, Notario de Madrid,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">--------------------------- COMPARECEN: ------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">--------------------------- De una parte: ---------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>DON ADRI</b>&#193;<b>N MACHO CURIEL, </b>mayor de edad, de nacionalidad espa&#241;ola, soltero, analista de inversiones, con domicilio a estos efectos en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Con D.N.I. y N.I.F. n&#250;mero 05.940.065-Q, vigente que me exhibe.--------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Y<b> DON PETER KHAYAT, </b>mayor de edad,<b> </b>de nacionalidad libanesa, soltero, consultor financiero, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Provisto de Tarjeta de Residencia y N.I.E. n&#250;mero Y5629675W, vigente que me exhibe.----------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Y de otra parte: <b>DON EMILIO PRIETO BEDOYA, </b>mayor de edad, de nacionalidad espa&#241;ola, soltero, con domicilio a estos efectos en el Paseo de la Castellana n&#250;mero 259 Cm 28046 Madrid. Con D.N.I. y N.I.F. n&#250;mero 72.034.312-Z, vigente que me exhibe.&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">--------------------------- INTERVIENEN:--------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1.- Don Adri&#225;n Macho Curiel, en nombre y representaci&#243;n como apoderado<b>, </b>de la compa&#241;&#237;a de nacionalidad espa&#241;ola denominada &#8220;<b>INVEREADY BIOTECH III, S.C.R., S.A.</b>&#8221;, con C.I.F. n&#250;mero A-88139399, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituida con una duraci&#243;n de diez a&#241;os por medio de la escritura otorgada el d&#237;a 8 de junio de 2.018, ante el Notario de Barcelona Don Jaime Agustin Justribo, con el n&#250;mero 2.253 de orden de protocolo; inscrita en el Registro Mercantil de San Sebasti&#225;n, en el tomo 2.961, folio 169, secci&#243;n 8&#170;, hoja n&#250;mero SS-43.025, inscripci&#243;n 1&#170; y en el Registro Especial de Sociedades de Capital Riesgo en la Comisi&#243;n Nacional del Mercado de Valores.&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">El objeto social de la sociedad, seg&#250;n manifiesta su representante es el propio de una sociedad de capital riesgo.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder a su favor conferido por acuerdo adoptado por el Consejo de Administraci&#243;n de la sociedad en su reuni&#243;n celebrada el d&#237;a 17 de julio de 2.021, elevado a p&#250;blico por medio de la escritura otorgada el d&#237;a 22 de julio de 2.021, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.548 de orden de protocolo.----------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.-Que me ha sido exhibida la copia autorizada de la escritura rese&#241;ada.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 8 de junio de 2.018, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.254 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2.- Don Peter Khayat,<b> </b>&nbsp;en nombre y representaci&#243;n como apoderada<b>, </b>de la compa&#241;&#237;a de nacionalidad espa&#241;ola denominada &#8220;<b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A.</b>&#8221;, A-88264130, con domicilio en Zuatzu Kalea, n&#250;mero 7, Edificio Urola, Local n&#186;1, Planta Baja, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituida con una duraci&#243;n de diez a&#241;os por medio de la escritura otorgada el d&#237;a 12 de noviembre de 2.018, ante el Notario de Barcelona Don Jaime Agustin Justrib&#243;, con el n&#250;mero 2.427 de orden de protocolo; inscrita en el Registro Mercantil de San Sebasti&#225;n, en el tomo 2.963, folio 1, secci&#243;n 8&#170;, hoja n&#250;mero Ss-43-031, inscripci&#243;n 1&#170;.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">El objeto social de la sociedad, seg&#250;n manifiesta su representante es el propio de una sociedad de capital riesgo.-----------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder a su favor conferido por el Consejo de Administraci&#243;n de la sociedad en su reuni&#243;n celebrada el d&#237;a 17 de julio de 2.021, elevado a p&#250;blico por medio de la escritura otorgada el d&#237;a 22 de julio de 2.021, ante el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 1.549 de orden de protocolo.--------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con esta escritura de apoderamiento, yo, el Notario, hago constar:&nbsp;&nbsp;</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.-Que me ha sido exhibida la copia autorizada de la escritura rese&#241;ada.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad de la poderdante.---------------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago constar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para el otorgamiento de la presente escritura.</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 12 de noviembre de 2.018, por el Notario de Barcelona Don Jaime Agust&#237;n Justrib&#243;, con el n&#250;mero 2.428 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

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<p style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin: 0pt; text-align: left">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3.- Don Emilio Prieto Bedoya, en nombre y representaci&#243;n, como apoderado de la sociedad &#8220;<b>DYADIC INTERNATIONAL (USA), INC</b>&#8221;, con n&#250;mero de identificaci&#243;n (EIN) 65-0645993, domiciliada en 140 Intracoastal Pointe Drive, Suite 404, Jupiter, Florida 33477, USA, debidamente constituida de conformidad con las leyes del Estado de Florida y provista de C.I.F. espa&#241;ol n&#250;mero N4008645F.-------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La actividad principal de la sociedad, seg&#250;n manifiesta su representante, es el desarrollo de actividades de biotecnolog&#237;a.--------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su legitimaci&#243;n para este acto resulta del poder especial a su favor conferido por Don Mark Emalfarb, como representante de la sociedad, el d&#237;a 6 de julio de 2021, ante el Notario de la ciudad de Florida, estados Unidos, Don Palm Beach County, Florida, Don Heidi Zosiak, cuya copia debidamente apostillada tengo a la vista. --</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">En relaci&#243;n con este apoderamiento, yo, el Notario hago constar:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1&#186;.- Que me ha exhibido el referido poder, que se encuentra redactado en idioma ingl&#233;s, idioma que en lo pertinente conozco.------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">2&#186;.- Que el apoderado manifiesta, bajo su responsabilidad, que el apoderamiento no ha sido revocado, suspendido o limitado, que no ha variado la capacidad del poderdante.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">3&#186;.- Yo, el Notario, hago contar que a mi juicio, las facultades representativas acreditadas son <u>suficientes</u> para la autorizaci&#243;n de la presente acta.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, el Notario hago constar que he cumplido con la obligaci&#243;n de identificar al titular real (persona con un porcentaje superior al veinticinco por ciento del capital social), por medio de un acta de manifestaciones autorizada el d&#237;a 30 de junio de 2.017, ante el Notario de Madrid Don Ignacio Mart&#237;nez-Gil Vich, con el n&#250;mero 1.986 de orden de protocolo, manifestando su representante no haberse modificado el contenido de la misma. Consultada la base de datos de titularidad real, compruebo que el titular real coincide con lo manifestado en dicha acta.-------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Tienen, a mi juicio, los comparecientes, seg&#250;n intervienen, la capacidad legal suficiente para formalizar la presente escritura de <b>COMPRAVENTA DE PARTICIPACIONES </b>y, al efecto,---------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">-------------------------------- EXPONEN<b>:</b> -------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">I.- Que la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, es titular en pleno dominio y por el titulo que se dir&#225; de setenta y cuatro mil ciento veintitr&#233;s (74.123) participaciones, n&#250;meros 1.778.955 al 1.853.077, ambos inclusive de diez (0,10) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;VLP THE VACCINES COMPANY, S.L.&#8221;, con CIF n&#250;mero B-37515111; con domicilio en 37005- Salamanca, calle Vel&#225;zquez, 4, 5&#186;A; constituida&nbsp; por tiempo indefinido bajo la denominaci&#243;n de &#8220;STAR2UP BUSINESS AND MANAGEMENT INVEST, S.L.&#8221; en escritura otorgada ante el Notario de Madrid, Don Andr&#233;s de la Fuente O&#8217;Connor, el d&#237;a 16 de marzo de 2.012, bajo el n&#250;mero 435 de orden de protocolo: Cambiada su denominaci&#243;n social por la actual, por medio de la escritura otorgada el d&#237;a 9 de abril de 2.012, ante el Notario de Madrid, Don Pedro Contreras Ranera, con el n&#250;mero 394 de orden de protocolo; inscrita en el Registro Mercantil de Salamanca, en el tomo 426, libro 0, folio 219, hoja, SA-14239, inscripci&#243;n 2&#170; de la hoja de la sociedad.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Su <u>objeto social</u> es el desarrollo de vacunas innovadoras, basadas en plataforma VLP, actividades de I + D en Biotecnolog&#237;a, servicios t&#233;cnicos, servicios tecnol&#243;gicos, servicios de asesoramiento tecnol&#243;gico, y desarrollo de f&#225;rmacos. ------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">TITULO.- Le pertenecen las referidas participaciones sociales por Escritura de Ampliaci&#243;n de Capital de fecha 30 de junio de 2017, otorgada ante el Notario de Madrid, D. Jose Luis Martinez Gil Vich, bajo el n&#250;mero de protocolo 1.812.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La presente transmisi&#243;n ha sido autorizada por la Junta General Extraordinaria y Universal de Socios celebrada en fecha 26 de julio de 2021, seg&#250;n resulta de la certificaci&#243;n que me exhibe, expedida el d&#237;a 26 de julio de 2021, por el Secretario no Consejero del Consejo de Administraci&#243;n de la sociedad, D. Borja D&#237;az-Guerra Heredero, con el visto bueno de su Presidente, D. Ricardo Arjona Antol&#237;n.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">CARGAS.- Manifiesta el representante de la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, que las referidas participaciones de su titularidad est&#225;n libres de cargas y grav&#225;menes.-----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">II. Que los comparecientes, en la presente fecha han otorgado ante m&#237; un acta de dep&#243;sito notarial bajo el n&#250;mero de protocolo &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;en virtud de la cual me han requerido para que libere el precio correspondiente a la presente compraventa con car&#225;cter inmediatamente posterior a su otorgamiento.----------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">III.- Que los comparecientes, seg&#250;n intervienen, tienen convenida la compraventa de las referidas participaciones, que se llevan a efecto por esta escritura, con arreglo a las siguientes,-------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">------------------------- ESTIPULACIONES:-----------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">PRIMERA.- La sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, por medio de su representante en este acto, <u>VENDE Y TRANSMITE</u> a INVEREADY BIOTECH III, S.C.R., S.A. y INVEREADY BIOTECH III PARALLEL, S.C.R., S.A., que <u>COMPRAN Y ADQUIEREN</u>, (74.123) participaciones, n&#250;meros 1.778.955 al 1.853.077, ambos inclusive de diez (0,10) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;VLP THE VACCINES COMPANY, S.L.&#8221;, totalmente desembolsadas, con cuanto a las mismas sea accesorio e inherente, y libres de toda carga, gravamen, trabas, embargos y pignoraciones conforme a continuaci&#243;n se indica:---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">INVEREADY BIOTECH III, S.C.R., S.A. adquiere (61.769) participaciones, n&#250;meros 1.778.956 al 1.840.723, ambos inclusive de diez (0,10) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;VLP THE VACCINES COMPANY, S.L.&#8221; por un precio total de 88.845,84 Euros.-------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">INVEREADY BIOTECH III PARALLEL, S.C.R., S.A. adquiere (12.354) participaciones, n&#250;meros 1.840.724 al 1.853.077, ambos inclusive de diez (0,10) c&#233;ntimos de valor nominal cada una de la sociedad &#8220;VLP THE VACCINES COMPANY, S.L.&#8221; por un precio total de 17.769,45 Euros.----------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SEGUNDA.- El precio de la compraventa es en conjunto de <b>CIENTO SEIS MIL SEISCIENTOS QUINCE EUROS CON VEINTINUVE CENTIMOS (106.615,29 </b>&#8364;<b>).</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">El precio de la compraventa ser&#225; abonado mediante transferencia bancaria y en la forma y t&#233;rminos y condiciones previstos en el acta de dep&#243;sito notarial autorizada por m&#237; el d&#237;a que hoy, con el n&#250;mero&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; de protocolo, en virtud de la cual acept&#233; el requerimiento de las partes compradoras y la parte vendedora de liberar los fondos correspondientes a la presente compraventa de participaciones.---------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">TERCERA.- Yo, el Notario, una vez otorgada la presente escritura realizar&#233; el pago del precio total de la compraventa a la parte vendedora mediante transferencia bancaria a la cuenta n&#250;mero &nbsp;&nbsp;SWIFT SNTRUS3AXXX n&#250;mero 1000090561274 titularidad de la parte vendedora.-------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Una vez realizada la transferencia, dejar&#233; incorporada a la presente escritura copia de dicha transferencia.---------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">CUARTA.-<b> </b>En este acto queda diligenciado un impreso modelo D-1B, correspondiente a la declaraci&#243;n de la liquidaci&#243;n de la inversi&#243;n extranjera realizada por la sociedad &#8220;DYADIC INTERNATIONAL (USA), INC&#8221;, dejando unido a esta matriz dicho impreso debidamente cumplimentado y presentado en el registro correspondiente.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">QUINTA.- Los gastos que se deriven de esta escritura ser&#225;n a cargo de la parte compradora.-----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">SEXTA.-<b> </b>Manifiestan los comparecientes que comunicar&#225;n la presente transmisi&#243;n al &#243;rgano de administraci&#243;n de la sociedad, con el fin de quedar esta anotada en el Libro Registro de Socios, tal como prev&#233; la Ley de Sociedades de Capital.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">S&#201;PTIMA.- La transmisi&#243;n que se realiza por medio de esta escritura est&#225; exenta del pago del Impuesto de Transmisiones Patrimoniales y actos Jur&#237;dicos Documentados (Art.314 RDL 4/2015 de 23 de octubre de 2.015, por el que se aprueba el Texto Refundido de la Ley del Mercado de Valores).-------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><u>PROTECCI</u>&#211;<u>N DE DATOS DE CAR</u>&#193;<u>CTER PERSONAL:</u>--</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">De conformidad con lo previsto en el Reglamento General de Protecci&#243;n de Datos europeo, se informa de que los datos personales de los intervinientes ser&#225;n tratados por el Notario autorizante, cuyos datos de contacto figuran en el presente documento. Los datos ser&#225;n tratados con la finalidad de realizar las funciones propias de la actividad notarial y para la facturaci&#243;n y gesti&#243;n de clientes, para lo cual se conservar&#225;n durante los plazos previstos en la normativa aplicable y, en cualquier caso, mientras se mantenga la relaci&#243;n con los interesados. ------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">La base del tratamiento es el desempe&#241;o de las funciones p&#250;blicas notariales, lo que obliga a que los datos sean facilitados al Notario e impedir&#237;a su intervenci&#243;n en caso contrario. Se realizar&#225;n las comunicaciones previstas en la Ley a las Administraciones P&#250;blicas y, en su caso, al Notario que suceda al actual en la plaza.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Los intervinientes tienen derecho a solicitar el acceso a sus datos personales, su rectificaci&#243;n, su supresi&#243;n, su portabilidad y la limitaci&#243;n de su tratamiento, as&#237; como oponerse a este. Frente a cualquier eventual vulneraci&#243;n de derechos, puede presentarse una reclamaci&#243;n ante la Agencia Espa&#241;ola de Protecci&#243;n de Datos. Si se facilitan datos de personas distintas de los intervinientes, estos deber&#225;n haberles informado previamente de todo lo previsto en el art&#237;culo 14 del RGPD.-------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">As&#237; lo dicen y otorgan los comparecientes, a quienes hago las reservas y advertencias legales, en especial y a efectos fiscales advierto de las obligaciones y responsabilidades tributarias que incumben a las partes en su aspecto material, formal y sancionador, y de las consecuencias de toda &#237;ndole que se derivar&#237;an de la inexactitud de sus declaraciones.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Doy cumplimiento al requisito de la lectura en la forma prevenida por el art&#237;culo 193 del Reglamento Notarial; tras la lectura, doy fe de que los comparecientes manifiestan haber quedado informados del contenido del instrumento p&#250;blico y prestar su libre consentimiento a este contenido, firmando conmigo Notario.---</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">Yo, Notario, DOY FE:----------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">a) De haber identificado a los comparecientes por medio de sus documentos de identidad, rese&#241;ados en la comparecencia, que me han sido exhibidos.&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">b) De que los comparecientes, <u>a mi juicio</u>, tienen capacidad y est&#225;n legitimados para el presente otorgamiento.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">c) De que el consentimiento de los otorgantes ha sido libremente prestado.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">d) De que el otorgamiento se adecua a la legalidad y a la voluntad libre y debidamente informada de los comparecientes.-------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">e) De que el presente instrumento p&#250;blico queda extendido en siete folios de papel de uso exclusivo para documentos notariales, serie GA, n&#250;meros el presente y los seis anteriores en orden correlativo, que signo, firmo y rubrico, de cuya adecuaci&#243;n y completo contenido doy fe.-</p>

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<p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: right;"><i><b>English Version only for information purposes</b></i></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b><u>PURCHASE AND SALE OF SHARES IN THE COMPANY "VLP THE VACCINES COMPANY, S.L.".---------------------------------------------------------- </u></b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">NUMBER THREE THOUSAND FOUR HUNDRED AND FIFTEEN.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">In Madrid, on the twenty-sixth day of July of the year two thousand and twenty-one.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">BEFORE ME, IGNACIO MARTINEZ-GIL VICH, Notary Public of Madrid,&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">--------------------------- APPEAR: -------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">--------------------------- On the one hand: --------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;"><b>Mr. ADRI</b>&#193;<b>N MACHO CURIEL</b>, of legal age, Spanish nationality, single, investment analyst, with address for these purposes at Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa). With D.N.I. and N.I.F. number 05.940.065-Q, in force and exhibited to me.------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">And <b>Mr. PETER KHAYAT</b>, of legal age, Lebanese nationality, single, financial consultant, with address at Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa). Provided with Residence Card and N.I.E. number Y5629675W, in force, which he exhibits to me.--------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">And on the other hand: <b>Mr. EMILIO PRIETO BEDOYA</b>, of legal age, of Spanish nationality, single, with address for these purposes at Paseo de la Castellana number 259 Cm 28046 Madrid. With D.N.I. and N.I.F. number 72.034.312-Z, in force and exhibited to me.----------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">--------------------------- INTERVENE:---------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;text-indent:36pt;">1.- Mr. Adri&#225;n Macho Curiel, on behalf of and representing as attorney-in-fact, the Spanish company called "<b>INVEREADY BIOTECH III, S.C.R., S.A.</b>", with C.I.F. number A-88139399, with address in Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituted with a duration of ten years by means of the deed granted on June 8, 2.018, before the Notary of Barcelona Mr. Jaime Agustin Justribo, with the number 2. 253 of the protocol order; registered in the Mercantile Registry of San Sebastian, in volume 2.961, folio 169, section 8&#170;, sheet number SS-43.025, inscription 1&#170; and in the Special Registry of Venture Capital Companies in the National Securities Market Commission (Comisi&#243;n Nacional del Mercado de Valores).</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The corporate purpose of the company, as stated by its representative, is that of a venture capital company.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">Its legitimacy for this act results from the power of attorney in its favor conferred by agreement adopted by the Board of Directors of the company at its meeting held on July 17, 2002, which was made public by means of the deed executed on July 22, 2002, before the Notary Public of Barcelona, Mr. Jaime Agust&#237;n Justrib&#243;, under number 1,548 of the protocol order.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">In relation to this deed of power of attorney, I, the Notary, state the following:&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">1&#186;.- That the authorized copy of the above-mentioned deed has been exhibited to me.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the attorney-in-fact has not changed.--------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I, the Notary, state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a deed of manifestations authorized on June 8, 2008, before the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 1,254 of the protocol order, stating that his representative has not modified the content of the same. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">2.- Mr. Peter Khayat, in the name and on behalf of the Spanish company "<b>INVEREADY BIOTECH III PARALLEL, S.C.R., S.A</b>.", A-88264130, with domicile in Zuatzu Kalea, number 7, Edificio Urola, Local n&#186;1, Ground Floor, 20018 San Sebasti&#225;n (Guip&#250;zcoa), constituted with a duration of ten years by means of the deed granted on November 12, 2. 018, before the Notary of Barcelona Mr. Jaime Agustin Justrib&#243;, with the number 2.427 of protocol order; registered in the Mercantile Registry of San Sebastian, in the volume 2.963, folio 1, section 8&#170;, sheet number Ss-43-031, inscription 1&#170;.----</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The corporate purpose of the company, according to its representative, is that of a venture capital company.------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">Its legitimacy for this act results from the power of attorney in its favor conferred by the Board of Directors of the company in its meeting held on July 17, 2.021, elevated to public by means of the deed granted on July 22, 2.021, before the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 1.549 of the protocol order.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">In relation to this power of attorney, I, the Notary,</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I hereby state for the record:--------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">1&#186;.- That the authorized copy of the aforementioned deed has been exhibited to me.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">3&#186;.- I, the Notary, state for the record that in my opinion, the accredited representative powers are sufficient for the execution of this deed.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I, the Notary, state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a deed of manifestations authorized on November 12, 2008, by the Notary Public of Barcelona Mr. Jaime Agust&#237;n Justrib&#243;, with the number 2,428 of the protocol order, stating that his representative has not modified the content of the same. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.----------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">3.- Mr. Emilio Prieto Bedoya, in the name and representation, as attorney-in-fact of the company "<b>DYADIC INTERNATIONAL (USA), INC</b>", with identification number (EIN) 65-0645993, domiciled at 140 Intracoastal Pointe Drive, Suite 404, Jupiter, Florida 33477, USA, duly constituted in accordance with the laws of the State of Florida and provided with Spanish C.I.F. number N4008645F.----------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The main activity of the company, according to its representative, is the development of biotechnology activities.--------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">Its legitimacy for this act results from the special power of attorney in its favor conferred by Mr. Mark Emalfarb, as representative of the company, on July 6, 2021, before the Notary of the city of Florida, United States, Mr. Palm Beach County, Florida, Mr. Heidi Zosiak, a duly apostilled copy of which I have before me. --------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">In connection with this power of attorney, I, the Notary, hereby state:</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">1&#186;.- That the aforementioned power of attorney has been exhibited to me, which is written in English, a language with which I am familiar.--------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">2&#186;.- That the attorney-in-fact declares, under his responsibility, that the power of attorney has not been revoked, suspended or limited, and that the capacity of the principal has not changed.-----------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">3&#186; - I, the Notary, state that in my opinion, the accredited representative powers are sufficient for the authorization of the present deed.---------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I, the Notary, state for the record that I have complied with the obligation to identify the beneficial owner (person with a percentage of more than twenty-five percent of the share capital), by means of a deed of manifestations authorized on June 30, 2007, before the Notary Public of Madrid Mr. Ignacio Mart&#237;nez-Gil Vich, with the number 1,986 of the protocol order, stating that his representative has not modified the content of the same. Having consulted the database of real ownership, I verify that the real owner coincides with what is stated in the said deed.----------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">In my opinion, the parties, as they intervene, have sufficient legal capacity to formalize the present deed of <b>PURCHASE AND SALE OF SHARES</b> and, to that effect,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">-------------------------------- EXHIBIT: ---------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I.- That the company "DYADIC INTERNATIONAL (USA), INC.", is the holder in full ownership and by the title to be stated of seventy-four thousand one hundred and twenty-three (74,123) shares, numbers 1,778,955 to 1,853,077, both inclusive of ten (0.10) cents of nominal value each of the company "VLP THE VACCINES COMPANY, S.L. "with CIF number B-37515111; domiciled in 37005- Salamanca, calle Vel&#225;zquez, 4, 5&#186;A; incorporated for an indefinite period of time under the name of "STAR2UP BUSINESS AND MANAGEMENT INVEST, S.L." in a deed executed before the Notary Public of Madrid, Mr. Andr&#233;s de la Fuente O'Connor, on March 16, 2012, under number 435 of the protocol order: Changed its corporate name to the current one, by means of the deed granted on April 9, 2012, before the Notary of Madrid, Mr. Pedro Contreras Ranera, under number 394 of protocol order; registered in the Mercantile Registry of Salamanca, in volume 426, book 0, folio 219, sheet, SA-14239, inscription 2&#170; of the company's sheet.&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">Its corporate purpose is the development of innovative vaccines based on VLP platform, R &amp; D activities in Biotechnology, technical services, technological services, technology consulting services, and drug development. ---------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">TITLE.- The aforementioned shares belong to it by Deed of Capital Increase dated June 30, 2017, granted before the Notary Public of Madrid, Mr. Jose Luis Martinez Gil Vich, under protocol number 1,812.------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">This transfer has been authorized by the Extraordinary and Universal General Shareholders' Meeting held on July 26, 2021, as shown in the certification exhibited to me, issued on July 26, 2021, by the Non-Director Secretary of the Board of Directors of the Company, Mr. Borja D&#237;az-Guerra Heredero, with the approval of its Chairman, Mr. Ricardo Arjona Antol&#237;n.--------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">CHARGES: The representative of the company "DYADIC INTERNATIONAL (USA), INC", declares that the referred shares of its ownership are free of charges and encumbrances.-------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">&nbsp;&nbsp;II. That the parties hereto, on this date, have executed before me a notarial deed of deposit under protocol number by virtue of which they have requested me to release the price corresponding to the present sale and purchase immediately after its execution.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">III.- That the parties, as intervening, have agreed the purchase and sale of the referred shares, which are carried into effect by this deed, in accordance with the following,&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">------------------------- PROVISIONS:------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">FIRST.- The company "DYADIC INTERNATIONAL (USA), INC", through its representative in this act, SELLS AND TRANSMITS to INVEREADY BIOTECH III, S.C.R., S.A. and INVEREADY BIOTECH III PARALLEL, S.C.R., S.A., that they PURCHASE AND ACQUIRE, (74,123) shares, numbers 1,778,955 to 1,853,077, both inclusive, of ten (0.10) cents of nominal value each, of the company "VLP THE VACCINES COMPANY, S.L.", fully paid up, with all that is accessory and inherent thereto, and free of all charges, liens, encumbrances, attachments and pledges as indicated below:--</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">INVEREADY BIOTECH III, S.C.R., S.A. acquires (61,769) shares, numbers 1,778,955 to 1,840,723, both inclusive, of ten (0.10) cents of nominal value each of the company "VLP THE VACCINES COMPANY, S.L." for a total price of 88,845.84 Euros.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">INVEREADY BIOTECH III PARALLEL, S.C.R., S.A. acquires (12,354) shares, numbers 1,840,724 to 1,853,077, both inclusive, of ten (0.10) cents of nominal value each of the company "VLP THE VACCINES COMPANY, S.L." for a total price of 17,769.45 Euros.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">SECOND.- The price of the sale and purchase is, as a whole<b>, ONE HUNDRED AND SIX THOUSAND SIX HUNDRED AND FIFTEEN EUROS AND TWENTY-NINE CENTS (106,615.29 </b>&#8364;<b>).</b>------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The price of the sale and purchase shall be paid by bank transfer and in the manner and terms and conditions set forth in the notarial deposit deed authorized by me today, with the protocol number, by virtue of which I accepted the requirement of the purchasing parties and the selling party to release the funds corresponding to the present sale and purchase of shares.--------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">THIRD.- I, the Notary Public, once this deed has been executed, will make the payment of the total price of the sale and purchase to the selling party by bank transfer to the SWIFT account number SNTRUS3AXXX number 1000090561274 owned by the selling party.--------------------------------------------------------------------------</p>

<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;">&nbsp;</p>

<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Once the transfer has been made, I will leave a copy of said transfer incorporated in this deed.-----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">FOURTH.- A form model D-1B, corresponding to the declaration of the liquidation of the foreign investment made by the company "DYADIC INTERNATIONAL (USA), INC" is hereby executed, leaving attached to this deed the said form duly completed and submitted to the corresponding registry.&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">FIFTH.- The expenses arising from this deed shall be borne by the purchaser.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">SIXTH.- The parties hereto declare that they will communicate the present transfer to the administrative body of the company, in order to be recorded in the Register of Shareholders, as provided for in the Capital Companies Act.---</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">SEVENTH.- The transfer carried out by means of this deed is exempt from the payment of the Transfer Tax and Documented Legal Acts (Art.314 RDL 4/2015 of 23 October 2015, which approves the Consolidated Text of the Securities Market Law).&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">PROTECTION OF PERSONAL DATA:-----------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">In accordance with the provisions of the European General Data Protection Regulation, it is hereby informed that the personal data of the intervening parties will be processed by the authorizing Notary, whose contact details appear in this document. The data will be processed for the purpose of carrying out the functions inherent to the notarial activity and for billing and client management, for which purpose they will be kept for the periods provided for in the applicable regulations and, in any case, for as long as the relationship with the interested parties is maintained. ---------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The basis of the processing is the performance of notarial public functions, which requires the data to be provided to the Notary and would otherwise prevent his intervention. The communications foreseen in the Law will be made to the Public Administrations and, where appropriate, to the Notary who succeeds the current Notary in the position.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">The intervening parties have the right to request access to their personal data, its rectification, deletion, portability and limitation of its processing, as well as to oppose its processing. In the event of any violation of rights, a complaint may be lodged with the Spanish Data Protection Agency. If data of persons other than the participants are provided, they must have previously informed them of all the provisions of Article 14 of the GDPR.---------------------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">This is so stated and granted by the parties, to whom I make the legal reservations and warnings, especially and for tax purposes I warn of the tax obligations and responsibilities incumbent on the parties in their material, formal and sanctioning aspect, and of the consequences of all kinds that would result from the inaccuracy of their declarations.----------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I comply with the requirement of the reading in the manner provided for in Article 193 of the Notarial Regulations; after the reading, I attest that the participants declare that they have been informed of the content of the public instrument and give their free consent to this content, signing with me, Notary.-----------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">I, Notary, WITNESS:------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">a) That I have identified the parties by means of their identity documents, as stated in the appearance, which have been exhibited to me.----------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">&nbsp;b) That the parties, in my opinion, have capacity and are legitimized for the present execution.--------------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">c) That the consent of the grantors has been freely given.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">d) That the grant is in accordance with the legality and the free and duly informed will of the parties.---------------------------------------------------------------</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 8pt;">e) That the present public instrument is drawn on seven sheets of paper for exclusive use for notarial documents, series GA, numbers the present and the six preceding ones in correlative order, which I sign, sign and initial, of whose adequacy and complete content I attest.-</p>

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<DESCRIPTION>EXHIBIT 10.3
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<p style="margin-bottom: 0px; text-align: right; margin-top: 0px"><font style="font-family: 'Times New Roman', Times, serif; font-size: 10pt"><b>Exhibit 10.3</b></font></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:center;margin:0pt;"><b>AMENDMENT N</b>&#186;<b>1 TO THE SERVICE FRAMEWORK AGREEMENT</b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt;">This <b>AMENDMENT N</b>&#186;<b>1 TO THE SERVICE FRAMEWORK AGREEMENT</b> (this &#8220;<b>Agreement</b>&#8221;), signed as of July 26, 2021, is entered into by and between DYADIC INTERNATIONAL, INC., a Delaware corporation with headquarters located at 140 Intracoastal Pointe Drive, Suite 404, Jupiter, Florida 33477-5094 USA and U.S. tax identification number 45-04867472 (&#8220;<b>Dyadic</b>&#8221;), and BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY IN PHARMACEUTICALS, S.L.U., a company incorporated under the laws of Spain having its registered office at Louist Proust 13, 47151 Boecillo (Valladolid), Spain, and identification code -CIF number- B-86206695 (&#8220;<b>BDI Pharmaceuticals</b>&#8221;).<b> </b>Dyadic and BDI Pharmaceuticals are sometimes collectively referred to as the &#8220;<b>Parties</b>&#8221; and individually as a &#8220;<b>Party</b>.&#8221;</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:center;margin:0pt;"><b>RECITALS:</b></p>

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			<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;margin:0pt;">I.</p>
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			<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;margin:0pt;">Dyadic and BDI Pharmaceuticals entered into a Service Framework Agreement dated on June 30<sup style="vertical-align:top;line-height:120%;font-size:pt">th</sup>, 2017;</p>
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			<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;margin:0pt;">Dyadic and BDI Pharmaceuticals are willing to extend the Term of the Service Framework Agreement to extend the collaboration under the same terms and conditions.</p>
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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt;"><b>NOW, THEREFORE, IN CONSIDERATION</b> of the mutual covenants contained in this Amendment, and the foregoing Recitals, which are incorporated herein and by this reference made a part hereof, and for other good and valuable consideration the receipt and adequacy of which hereby are mutually acknowledged by Dyadic and BDI Pharmaceuticals, the Parties hereby agree as follows:</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:center;margin:0pt;"><b><u>ARTICLE 1</u></b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;margin:0pt;">Amend Article 8 of the Agreement as follows:</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; text-align: center; margin: 0pt;"><b>ARTICLE 8</b><br>
<b>TERM AND TERMINATION</b></p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 29pt;"><b>8.1</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Term</b>. This Agreement shall enter into force upon the closing of the transactions contemplated by the Investment Agreement (the &#8220;<b>Effective Date</b>&#8221;) and shall expire June 30, 2025 (the &#8220;<b>Term</b>&#8221;), excluding the Articles and Sections and their legal effects of which are meant to survive the termination or expiration of the Agreement.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt 0pt 0pt 29pt;"><b>8.2</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Termination in the Event of Insolvency</b>. Either Party may terminate this Agreement if the other Party becomes insolvent, voluntarily files a petition for relief under bankruptcy or any similar or other insolvency laws (or has a petition filed against it and the same remains undischarged or unstayed for sixty (60) days) or voluntarily or involuntarily enters receivership or any similar or other insolvency proceeding.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>8.3</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Termination for Breach</b>. Without prejudice to any other damages or remedies available under applicable law and/or this Agreement, either Party has the right, at any time, to terminate this Agreement or any Statement of Work hereunder by written notice and without further formality upon a breach by the other Party in the performance of the provisions of this Agreement or such Statement of Work, provided such breach is not cured within thirty (30) days following receipt by the defaulting Party of a written notice from the non-defaulting Party to remedy such breach. However, (i) in case of a breach, which is not capable of being cured; or (ii) where any Party repeatedly or consistently fails to meet its contractual obligations following an initial cure period, the other Party has the right to terminate this Agreement or such Statement of Work immediately, by written notice and without any further formality and (additional) cure period.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>8.4</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Termination by Dyadic or Sponsor</b>. Dyadic may terminate this Agreement, at its sole option, in its entirety or Sponsor may terminate any Statement of Work, at any time upon either (i) thirty (30) days written notice to BDI Pharmaceuticals, if no Statements of Work are operational under the Agreement at the time of termination and the date of termination; (ii) upon ninety (90) days written notice to BDI Pharmaceuticals;</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>8.5</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Termination by BDI Pharmaceuticals</b>. After July 26, 2025, BDI Pharmaceuticals may terminate this Agreement in writing, at its sole option, in its entirety at any time upon one hundred and eighty (180) days written notice to Dyadic, if there are no active Statements of Work and no Projects have been contracted by Dyadic under this Agreement during the six (6) month period immediately prior to the termination date.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>8.6</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<b>Effect of Termination</b>.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-indent: 36pt; text-align: justify;">(a)&nbsp;&nbsp;&nbsp;&nbsp;<u>Accrued Rights and Obligations</u>. Termination of this Agreement or a Statement of Work hereunder for any reason shall not release any Party from any obligation which, at the time of such termination, has already accrued and become due to the other Party or which is attributable to a period prior to such termination nor preclude either Party from pursuing any rights and remedies it may have hereunder or at law or in equity with respect to any breach of this Agreement.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-indent: 36pt; text-align: justify;">(b)&nbsp;&nbsp;&nbsp;&nbsp;<u>Return of Confidential Information and Materials</u>. Upon any termination of this Agreement, BDI Pharmaceuticals shall promptly return to Sponsor all Confidential Information and Materials received from or on behalf of Sponsor. BDI Pharmaceuticals may retain a copy of the Confidential Information that must thereafter be used solely as a legal record of the Confidential Information under this Agreement.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-indent: 36pt; text-align: justify;">(c)&nbsp;&nbsp;&nbsp;&nbsp;<u>Destruction of Confidential Information and Materials</u>. Upon any termination of this Agreement, Sponsor may request BDI Pharmaceuticals to destroy all Confidential Information and Materials received from or on behalf of Sponsor instead of returning it in accordance with paragraph (b) above. BDI Pharmaceuticals may retain a copy of the Confidential Information that must thereafter be used solely as a legal record of the Confidential Information under this Agreement.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-indent: 36pt; text-align: justify;">(d)&nbsp;&nbsp;&nbsp;&nbsp;<u>Rights in IP</u>. In the event of termination of this Agreement either on or prior to the expiration of the Term by either Party, all rights and licenses of BDI Pharmaceuticals to Background IP and Results shall automatically terminate and/or revert back to Sponsor and any license grants from Dyadic to BDI Pharmaceuticals, such, for example, without limitation, the license grants provided in Article 4 shall terminate.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-indent: 36pt; text-align: justify;">(e)&nbsp;&nbsp;&nbsp;&nbsp;<u>Other Remedies Available</u>. Notwithstanding anything in this Agreement to the contrary, in the event of termination of this Agreement, each Party shall have available every remedy allowed under law and equity, including but not limited to specific performance, suit for damages, and rescission.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>8.7</b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<u>Survival</u>. Termination of a Statement of Work shall not result in a termination of the entire Agreement unless so stated in the termination notice. Notwithstanding anything to the contrary contained herein, the provisions of Recital VI, Article 1, Section 2.3, Section 3.1, Section 3.4, Section 4.1 through Section 4.3, Section 4.5 through Section 4.8, Article 5 through Article 7, Section 8.6, Section 8.7, Article 9 shall survive any termination of this Agreement.</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: center;"><b><u>ARTICLE 2</u></b></p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: justify;">Amend Article 9.12 of the Agreement as follows:</p>

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<p style="font-family: Times New Roman; font-size: 10pt; font-variant: normal; margin: 0pt 0pt 0pt 29pt; text-align: justify;"><b>9.12</b> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Non-Compete. During the term of this Agreement and until June 30, 2030, BDI Pharmaceuticals agrees that it, and its affiliates, will not work on C1 Strains for anyone other than Dyadic on pharmaceutical applications and/or processes (animal or human, including but not limited to active pharmaceutical ingredients or catalysts) unless so authorized by the CEO of Dyadic. BDI Pharmaceuticals shall cause the substance of this clause to be included in any sub-contract for performance of Services hereunder. For the purposes of this Section, &#8220;C1 Strains&#8221; shall be defined as and fungal strain(s) that have the taxonomy of either (i) Thermothelomyces heterothallica, (ii) Myceliophthora thermophila, (ii) Corynascus or (iv) Sporotrichium and any strains derived or generated from the C1 Strains transferred hereunder in (i) the Project, (ii) under the prior Agreement or (iii) this Agreement.</p>

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<p style="font-family:Times New Roman;font-size:10pt;font-variant:normal;text-align:justify;margin:0pt;">IN WITNESS WHEREOF, the parties have caused this Agreement to be executed in two counterparts by their duly authorized representatives, each Party acknowledging receipt of one original.</p>

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			<td colspan="2" rowspan="1" style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; vertical-align: top;"><b>DYADIC INTERNATIONAL, INC.</b></td>
			<td style="width: 4%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">&nbsp;</td>
			<td colspan="2" rowspan="1" style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt; vertical-align: top;"><b>BIOTECHNOLOGY DEVELOPMENTS FOR INDUSTRY IN PHARMACEUTICALS, S.L.U.</b></td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">By:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">/s/ Mark A. Emalfarb</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">By:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">/s/ Emilio&nbsp;Guti&#233;rrez G&#243;mez</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Name:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Mark A. Emalfarb</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Name:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Emilio Guti&#233;rrez G&#243;mez</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Title:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Chief Executive Officer</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Title:</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Legal Representative</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Date: &nbsp;</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">26<sup style="vertical-align:top;line-height:120%;font-size:pt">th</sup> July 2021&nbsp;</td>
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			<td style="width: 5%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">Date: &nbsp;</td>
			<td style="border-bottom: thin solid rgb(0, 0, 0); width: 43%; font-family: &quot;Times New Roman&quot;, Times, serif; font-size: 10pt;">26<sup style="vertical-align:top;line-height:120%;font-size:pt">th</sup> July 2021</td>
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<xsd:import namespace="http://xbrl.sec.gov/dei/2020-01-31" schemaLocation="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd"/>
<xsd:import namespace="http://xbrl.sec.gov/country/2020-01-31" schemaLocation="https://xbrl.sec.gov/country/2020/country-2020-01-31.xsd"/>
<xsd:import namespace="http://xbrl.sec.gov/sic/2020-01-31" schemaLocation="https://xbrl.sec.gov/sic/2020/sic-2020-01-31.xsd"/>
<xsd:import namespace="http://xbrl.sec.gov/currency/2020-01-31" schemaLocation="https://xbrl.sec.gov/currency/2020/currency-2020-01-31.xsd"/>
<xsd:import namespace="http://xbrl.sec.gov/exch/2020-01-31" schemaLocation="https://xbrl.sec.gov/exch/2020/exch-2020-01-31.xsd"/>

<xsd:annotation>
<xsd:appinfo>
<link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="dyai-20210726_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
<link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="dyai-20210726_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
<link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="dyai-20210726_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
<link:roleType id="statement-document-and-entity-information" roleURI="http://www.dyai.com/20210726/role/statement-document-and-entity-information">
<link:definition xmlns="http://www.xbrl.org/2003/linkbase">000 - Document - Document And Entity Information</link:definition>
<link:usedOn>link:calculationLink</link:usedOn>
<link:usedOn>link:definitionLink</link:usedOn>
<link:usedOn>link:presentationLink</link:usedOn>
</link:roleType>
</xsd:appinfo>
</xsd:annotation>
<xsd:element abstract="true" id="dyai_DocumentAndEntityInformation" name="DocumentAndEntityInformation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.DEF
<SEQUENCE>6
<FILENAME>dyai-20210726_def.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION DEFINITION LINKBASE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
<!--Generated by ThunderDome Portal - 7/27/2021 12:09:34 PM-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" xlink:type="simple"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" xlink:type="simple"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" xlink:type="simple"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" xlink:type="simple"/>
<link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" xlink:type="simple"/>
<link:roleRef roleURI="http://www.dyai.com/20210726/role/statement-document-and-entity-information" xlink:href="dyai-20210726.xsd#statement-document-and-entity-information" xlink:type="simple"/>
<link:definitionLink xlink:role="http://www.dyai.com/20210726/role/statement-document-and-entity-information" xlink:type="extended">
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain" xlink:label="dei_EntityDomain" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain" xlink:label="dei_EntityDomain-default" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationTable" xlink:label="dei_DocumentInformationTable" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationLineItems" xlink:label="dei_DocumentInformationLineItems" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LegalEntityAxis" xlink:label="dei_LegalEntityAxis" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType" xlink:label="dei_DocumentType" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName" xlink:label="dei_EntityRegistrantName" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber" xlink:label="dei_EntityFileNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="dei_EntityTaxIdentificationNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="dei_EntityAddressAddressLine1" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications" xlink:label="dei_WrittenCommunications" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial" xlink:label="dei_SolicitingMaterial" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer" xlink:label="dei_PreCommencementTenderOffer" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="dei_PreCommencementIssuerTenderOffer" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle" xlink:label="dei_Security12bTitle" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol" xlink:label="dei_TradingSymbol" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName" xlink:label="dei_SecurityExchangeName" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="dei_EntityCentralIndexKey" xlink:type="locator"/>
<link:definitionArc order="0" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="dei_LegalEntityAxis" xlink:to="dei_EntityDomain" xlink:type="arc"/>
<link:definitionArc order="1" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="dei_LegalEntityAxis" xlink:to="dei_EntityDomain-default" xlink:type="arc"/>

<link:definitionArc order="0" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="dei_DocumentInformationTable" xlink:to="dei_LegalEntityAxis" xlink:type="arc"/>


<link:definitionArc order="0" xbrldt:closed="true" xbrldt:contextElement="segment" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_DocumentInformationTable" xlink:type="arc"/>
<link:definitionArc order="1" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_DocumentType" xlink:type="arc"/>
<link:definitionArc order="2" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_DocumentPeriodEndDate" xlink:type="arc"/>
<link:definitionArc order="3" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityRegistrantName" xlink:type="arc"/>
<link:definitionArc order="4" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityIncorporationStateCountryCode" xlink:type="arc"/>
<link:definitionArc order="5" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityFileNumber" xlink:type="arc"/>
<link:definitionArc order="6" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityTaxIdentificationNumber" xlink:type="arc"/>
<link:definitionArc order="7" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressAddressLine1" xlink:type="arc"/>
<link:definitionArc order="8" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressCityOrTown" xlink:type="arc"/>
<link:definitionArc order="9" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressStateOrProvince" xlink:type="arc"/>
<link:definitionArc order="10" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressPostalZipCode" xlink:type="arc"/>
<link:definitionArc order="11" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_CityAreaCode" xlink:type="arc"/>
<link:definitionArc order="12" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_LocalPhoneNumber" xlink:type="arc"/>
<link:definitionArc order="13" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_WrittenCommunications" xlink:type="arc"/>
<link:definitionArc order="14" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_SolicitingMaterial" xlink:type="arc"/>
<link:definitionArc order="15" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_PreCommencementTenderOffer" xlink:type="arc"/>
<link:definitionArc order="16" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_PreCommencementIssuerTenderOffer" xlink:type="arc"/>
<link:definitionArc order="17" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityEmergingGrowthCompany" xlink:type="arc"/>
<link:definitionArc order="18" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_Security12bTitle" xlink:type="arc"/>
<link:definitionArc order="19" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_TradingSymbol" xlink:type="arc"/>
<link:definitionArc order="20" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_SecurityExchangeName" xlink:type="arc"/>
<link:definitionArc order="21" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_AmendmentFlag" xlink:type="arc"/>
<link:definitionArc order="22" xbrldt:closed="true" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityCentralIndexKey" xlink:type="arc"/>

</link:definitionLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>7
<FILENAME>dyai-20210726_lab.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
<!--Generated by ThunderDome Portal - 7/27/2021 12:09:34 PM-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple"/>
<link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple"/>
<link:labelLink xlink:role="http://www.xbrl.org/2003/role/link" xlink:type="extended">
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain" xlink:label="dei_EntityDomain" xlink:type="locator"/>
<link:label xlink:label="dei_EntityDomain-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity [Domain]</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityDomain" xlink:to="dei_EntityDomain-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LegalEntityAxis" xlink:label="dei_LegalEntityAxis" xlink:type="locator"/>
<link:label xlink:label="dei_LegalEntityAxis-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Legal Entity [Axis]</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LegalEntityAxis" xlink:to="dei_LegalEntityAxis-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationLineItems" xlink:label="dei_DocumentInformationLineItems" xlink:type="locator"/>
<link:label xlink:label="dei_DocumentInformationLineItems-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Line Items]</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_DocumentInformationLineItems-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationTable" xlink:label="dei_DocumentInformationTable" xlink:type="locator"/>
<link:label xlink:label="dei_DocumentInformationTable-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Table]</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentInformationTable" xlink:to="dei_DocumentInformationTable-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType" xlink:label="dei_DocumentType" xlink:type="locator"/>
<link:label xlink:label="dei_DocumentType-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document, Type</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentType" xlink:to="dei_DocumentType-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate" xlink:type="locator"/>
<link:label xlink:label="dei_DocumentPeriodEndDate-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document, Period End Date</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodEndDate" xlink:to="dei_DocumentPeriodEndDate-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName" xlink:label="dei_EntityRegistrantName" xlink:type="locator"/>
<link:label xlink:label="dei_EntityRegistrantName-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Registrant Name</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityRegistrantName" xlink:to="dei_EntityRegistrantName-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode" xlink:type="locator"/>
<link:label xlink:label="dei_EntityIncorporationStateCountryCode-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Incorporation, State or Country Code</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber" xlink:label="dei_EntityFileNumber" xlink:type="locator"/>
<link:label xlink:label="dei_EntityFileNumber-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, File Number</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFileNumber" xlink:to="dei_EntityFileNumber-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="dei_EntityTaxIdentificationNumber" xlink:type="locator"/>
<link:label xlink:label="dei_EntityTaxIdentificationNumber-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Tax Identification Number</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityTaxIdentificationNumber" xlink:to="dei_EntityTaxIdentificationNumber-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="dei_EntityAddressAddressLine1" xlink:type="locator"/>
<link:label xlink:label="dei_EntityAddressAddressLine1-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Address, Address Line One</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine1" xlink:to="dei_EntityAddressAddressLine1-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown" xlink:type="locator"/>
<link:label xlink:label="dei_EntityAddressCityOrTown-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Address, City or Town</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCityOrTown" xlink:to="dei_EntityAddressCityOrTown-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince" xlink:type="locator"/>
<link:label xlink:label="dei_EntityAddressStateOrProvince-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Address, State or Province</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressStateOrProvince" xlink:to="dei_EntityAddressStateOrProvince-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode" xlink:type="locator"/>
<link:label xlink:label="dei_EntityAddressPostalZipCode-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Address, Postal Zip Code</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressPostalZipCode" xlink:to="dei_EntityAddressPostalZipCode-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode" xlink:type="locator"/>
<link:label xlink:label="dei_CityAreaCode-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">City Area Code</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CityAreaCode" xlink:to="dei_CityAreaCode-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber" xlink:type="locator"/>
<link:label xlink:label="dei_LocalPhoneNumber-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Local Phone Number</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LocalPhoneNumber" xlink:to="dei_LocalPhoneNumber-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications" xlink:label="dei_WrittenCommunications" xlink:type="locator"/>
<link:label xlink:label="dei_WrittenCommunications-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Written Communications</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_WrittenCommunications" xlink:to="dei_WrittenCommunications-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial" xlink:label="dei_SolicitingMaterial" xlink:type="locator"/>
<link:label xlink:label="dei_SolicitingMaterial-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Soliciting Material</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SolicitingMaterial" xlink:to="dei_SolicitingMaterial-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer" xlink:label="dei_PreCommencementTenderOffer" xlink:type="locator"/>
<link:label xlink:label="dei_PreCommencementTenderOffer-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Pre-commencement Tender Offer</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementTenderOffer" xlink:to="dei_PreCommencementTenderOffer-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="dei_PreCommencementIssuerTenderOffer" xlink:type="locator"/>
<link:label xlink:label="dei_PreCommencementIssuerTenderOffer-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Pre-commencement Issuer Tender Offer</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementIssuerTenderOffer" xlink:to="dei_PreCommencementIssuerTenderOffer-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany" xlink:type="locator"/>
<link:label xlink:label="dei_EntityEmergingGrowthCompany-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Emerging Growth Company</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityEmergingGrowthCompany" xlink:to="dei_EntityEmergingGrowthCompany-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle" xlink:label="dei_Security12bTitle" xlink:type="locator"/>
<link:label xlink:label="dei_Security12bTitle-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Title of 12(b) Security</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12bTitle" xlink:to="dei_Security12bTitle-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol" xlink:label="dei_TradingSymbol" xlink:type="locator"/>
<link:label xlink:label="dei_TradingSymbol-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Trading Symbol</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_TradingSymbol" xlink:to="dei_TradingSymbol-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName" xlink:label="dei_SecurityExchangeName" xlink:type="locator"/>
<link:label xlink:label="dei_SecurityExchangeName-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Security Exchange Name</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityExchangeName" xlink:to="dei_SecurityExchangeName-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag" xlink:type="locator"/>
<link:label xlink:label="dei_AmendmentFlag-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amendment Flag</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentFlag" xlink:to="dei_AmendmentFlag-label" xlink:type="arc"/>

<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="dei_EntityCentralIndexKey" xlink:type="locator"/>
<link:label xlink:label="dei_EntityCentralIndexKey-label" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity, Central Index Key</link:label>
<link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCentralIndexKey" xlink:to="dei_EntityCentralIndexKey-label" xlink:type="arc"/>

</link:labelLink>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>8
<FILENAME>dyai-20210726_pre.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="US-ASCII" standalone="no"?>
<!--Generated by ThunderDome Portal - 7/27/2021 12:09:34 PM-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
<link:roleRef roleURI="http://www.dyai.com/20210726/role/statement-document-and-entity-information" xlink:href="dyai-20210726.xsd#statement-document-and-entity-information" xlink:type="simple"/>
<link:presentationLink xlink:role="http://www.dyai.com/20210726/role/statement-document-and-entity-information" xlink:type="extended">
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain" xlink:label="dei_EntityDomain" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LegalEntityAxis" xlink:label="dei_LegalEntityAxis" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationTable" xlink:label="dei_DocumentInformationTable" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentInformationLineItems" xlink:label="dei_DocumentInformationLineItems" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType" xlink:label="dei_DocumentType" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="dei_DocumentPeriodEndDate" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName" xlink:label="dei_EntityRegistrantName" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="dei_EntityIncorporationStateCountryCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber" xlink:label="dei_EntityFileNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="dei_EntityTaxIdentificationNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="dei_EntityAddressAddressLine1" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="dei_EntityAddressCityOrTown" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="dei_EntityAddressStateOrProvince" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="dei_EntityAddressPostalZipCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode" xlink:label="dei_CityAreaCode" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber" xlink:label="dei_LocalPhoneNumber" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications" xlink:label="dei_WrittenCommunications" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial" xlink:label="dei_SolicitingMaterial" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer" xlink:label="dei_PreCommencementTenderOffer" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="dei_PreCommencementIssuerTenderOffer" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="dei_EntityEmergingGrowthCompany" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle" xlink:label="dei_Security12bTitle" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol" xlink:label="dei_TradingSymbol" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName" xlink:label="dei_SecurityExchangeName" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag" xlink:label="dei_AmendmentFlag" xlink:type="locator"/>
<link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="dei_EntityCentralIndexKey" xlink:type="locator"/>
<link:presentationArc order="0" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_LegalEntityAxis" xlink:to="dei_EntityDomain" xlink:type="arc"/>

<link:presentationArc order="0" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationTable" xlink:to="dei_LegalEntityAxis" xlink:type="arc"/>

<link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationTable" xlink:to="dei_DocumentInformationLineItems" xlink:type="arc"/>
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<link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_DocumentType" xlink:type="arc"/>
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<link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityFileNumber" xlink:type="arc"/>
<link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityTaxIdentificationNumber" xlink:type="arc"/>
<link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressAddressLine1" xlink:type="arc"/>
<link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressCityOrTown" xlink:type="arc"/>
<link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressStateOrProvince" xlink:type="arc"/>
<link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityAddressPostalZipCode" xlink:type="arc"/>
<link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_CityAreaCode" xlink:type="arc"/>
<link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_LocalPhoneNumber" xlink:type="arc"/>
<link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_WrittenCommunications" xlink:type="arc"/>
<link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_SolicitingMaterial" xlink:type="arc"/>
<link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_PreCommencementTenderOffer" xlink:type="arc"/>
<link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_PreCommencementIssuerTenderOffer" xlink:type="arc"/>
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<link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_TradingSymbol" xlink:type="arc"/>
<link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_SecurityExchangeName" xlink:type="arc"/>
<link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_AmendmentFlag" xlink:type="arc"/>
<link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/label" xbrldt:closed="true" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_DocumentInformationLineItems" xlink:to="dei_EntityCentralIndexKey" xlink:type="arc"/>

</link:presentationLink>
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<DOCUMENT>
<TYPE>XML
<SEQUENCE>9
<FILENAME>dyai20210616_8k_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version="1.0" encoding="utf-8"?>
<xbrl
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  xmlns:dei="http://xbrl.sec.gov/dei/2020-01-31"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:xlink="http://www.w3.org/1999/xlink">
    <link:schemaRef xlink:href="dyai-20210726.xsd" xlink:type="simple"/>
    <context id="d20218K">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001213809</identifier>
        </entity>
        <period>
            <startDate>2021-07-26</startDate>
            <endDate>2021-07-26</endDate>
        </period>
    </context>
    <dei:AmendmentFlag contextRef="d20218K">false</dei:AmendmentFlag>
    <dei:EntityCentralIndexKey contextRef="d20218K">0001213809</dei:EntityCentralIndexKey>
    <dei:DocumentType contextRef="d20218K">8-K</dei:DocumentType>
    <dei:DocumentPeriodEndDate contextRef="d20218K">2021-07-26</dei:DocumentPeriodEndDate>
    <dei:EntityRegistrantName contextRef="d20218K">Dyadic International, Inc.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode contextRef="d20218K">DE</dei:EntityIncorporationStateCountryCode>
    <dei:EntityFileNumber contextRef="d20218K">000-55264</dei:EntityFileNumber>
    <dei:EntityTaxIdentificationNumber contextRef="d20218K">45-0486747</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1 contextRef="d20218K">140 Intracoastal Pointe Drive, Suite 404</dei:EntityAddressAddressLine1>
    <dei:EntityAddressCityOrTown contextRef="d20218K">Jupiter</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince contextRef="d20218K">FL</dei:EntityAddressStateOrProvince>
    <dei:EntityAddressPostalZipCode contextRef="d20218K">33477</dei:EntityAddressPostalZipCode>
    <dei:CityAreaCode contextRef="d20218K">561</dei:CityAreaCode>
    <dei:LocalPhoneNumber contextRef="d20218K">743-8333</dei:LocalPhoneNumber>
    <dei:WrittenCommunications contextRef="d20218K">false</dei:WrittenCommunications>
    <dei:SolicitingMaterial contextRef="d20218K">false</dei:SolicitingMaterial>
    <dei:PreCommencementTenderOffer contextRef="d20218K">false</dei:PreCommencementTenderOffer>
    <dei:PreCommencementIssuerTenderOffer contextRef="d20218K">false</dei:PreCommencementIssuerTenderOffer>
    <dei:EntityEmergingGrowthCompany contextRef="d20218K">false</dei:EntityEmergingGrowthCompany>
    <dei:Security12bTitle contextRef="d20218K">Common Stock</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="d20218K">DYAI</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="d20218K">NASDAQ</dei:SecurityExchangeName>
</xbrl>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>10
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
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</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140451600551480">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Document And Entity Information<br></strong></div></th>
<th class="th"><div>Jul. 26, 2021</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentInformationLineItems', window );"><strong>Document Information [Line Items]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity, Registrant Name</a></td>
<td class="text">Dyadic International, Inc.<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentType', window );">Document, Type</a></td>
<td class="text">8-K<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document, Period End Date</a></td>
<td class="text">Jul. 26,  2021<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity, Incorporation, State or Country Code</a></td>
<td class="text">DE<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity, File Number</a></td>
<td class="text">000-55264<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity, Tax Identification Number</a></td>
<td class="text">45-0486747<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity, Address, Address Line One</a></td>
<td class="text">140 Intracoastal Pointe Drive, Suite 404<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity, Address, City or Town</a></td>
<td class="text">Jupiter<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity, Address, State or Province</a></td>
<td class="text">FL<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity, Address, Postal Zip Code</a></td>
<td class="text">33477<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">561<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">743-8333<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_WrittenCommunications', window );">Written Communications</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SolicitingMaterial', window );">Soliciting Material</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_PreCommencementTenderOffer', window );">Pre-commencement Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_PreCommencementIssuerTenderOffer', window );">Pre-commencement Issuer Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityEmergingGrowthCompany', window );">Entity, Emerging Growth Company</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Common Stock<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">DYAI<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity, Central Index Key</a></td>
<td class="text">0001213809<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentInformationLineItems">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentInformationLineItems</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The end date of the period reflected on the cover page if a periodic report. For all other reports and registration statements containing historical data, it is the date up through which that historical data is presented.  If there is no historical data in the report, use the filing date. The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
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<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
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<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityEmergingGrowthCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate if registrant meets the emerging growth company criteria.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityEmergingGrowthCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
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<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
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<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementIssuerTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 13e<br> -Subsection 4c<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementIssuerTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 14d<br> -Subsection 2b<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_Security12bTitle">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Title of a 12(b) registered security.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_Security12bTitle</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:securityTitleItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SecurityExchangeName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the Exchange on which a security is registered.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection d1-1<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SecurityExchangeName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarExchangeCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SolicitingMaterial">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Section 14a<br> -Number 240<br> -Subsection 12<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SolicitingMaterial</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
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<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_TradingSymbol">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Trading symbol of an instrument as listed on an exchange.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_TradingSymbol</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:tradingSymbolItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
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<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_WrittenCommunications">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Securities Act<br> -Number 230<br> -Section 425<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_WrittenCommunications</td>
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<td>dei_</td>
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<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
