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Note 4 - Income Taxes - Component of Deferred Tax Assets (Details) - USD ($) | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Stock option expense | $ 947,400 | $ 689,600
NOL carryforward | 10,509,900 | 7,080,600
Research and development credits | 1,656,500 | 1,656,500
Unrealized gain from investment in Alphazyme | (72,100) | (69,800)
Other | (6,100) | 7,900
Deferred tax asset, net of deferred tax liabilities | 13,035,600 | 9,364,800
Valuation allowance | (13,035,600) | (9,364,800)
Net deferred tax asset | $ 0 | $ 0

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