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Note 1 - Organization and Summary of Significant Accounting Policies - Accounts Payable (Details) - USD ($) | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Research and development expenses | $ 1,363,889 | $ 904,572
Legal expenses | 27,675 | 24,496
Other | 156,389 | 84,031
Accounts Payable, Current, Total | $ 1,547,953 | $ 1,013,099

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