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v3.22.1

Note 1 - Organization and Summary of Significant Accounting Policies (Details Textual) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2021 USD ($) | Dec. 31, 2021 USD ($) shares | Dec. 31, 2020 USD ($) shares
Number of Operating Segments |  | 1 |
Revenue from Contract with Customer, Excluding Assessed Tax, Total |  | $ 2,403,831 | $ 1,601,921
Accounts Receivable, Allowance for Credit Loss, Ending Balance |  | $ 0 | $ 0
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) | shares |  | 4,774,215 | 4,638,390
Alphazyme [Member] |  |  |
Equity Securities without Readily Determinable Fair Value, Amount |  |  | $ 284,709
BDI Holdings [Member] |  |  |
Proceeds from Sales of Business, Affiliate and Productive Assets | $ 1,600,000 | $ 1,600,000 |
Customer Concentration Risk [Member] | Revenue Benchmark [Member] |  |  |
Concentration Risk, Number of Customers |  | 14 | 14
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Non-US [Member] |  |  |
Concentration Risk, Number of Customers |  | 8 | 7
Revenue from Contract with Customer, Excluding Assessed Tax, Total |  | $ 1,716,000 | $ 796,000
Concentration Risk, Percentage |  | 71.30% | 49.70%
Customer Concentration Risk [Member] | Accounts Receivable [Member] |  |  |
Concentration Risk, Number of Customers |  | 8 | 9
Customer Concentration Risk [Member] | Accounts Receivable [Member] | Non-US [Member] |  |  |
Concentration Risk, Number of Customers |  | 4 | 7
Concentration Risk, Percentage |  | 56.40% | 41.60%
Accounts Receivable, after Allowance for Credit Loss, Total |  | $ 157,000 | $ 123,000
Supplier Concentration Risk [Member] | Contract Research Organizations [Member] |  |  |
Concentration Risk, Number of Suppliers |  | 3 | 1
Supplier Concentration Risk [Member] | Contract Research Organizations [Member] | Three CROs [Member] |  |  |
Concentration Risk, Percentage |  | 95.10% |
Research Services Purchased |  | $ 9,061,000 |
Supplier Concentration Risk [Member] | Contract Research Organizations [Member] | One CRO [Member] |  |  |
Concentration Risk, Percentage |  |  | 91.60%
Research Services Purchased |  |  | $ 4,576,000
Supplier Concentration Risk [Member] | Accounts Payable [Member] |  |  |
Concentration Risk, Number of Suppliers |  | 2 | 1
Supplier Concentration Risk [Member] | Accounts Payable [Member] | One CRO [Member] |  |  |
Concentration Risk, Percentage |  |  | 68.10%
Accounts Payable, Total |  |  | $ 690,000
Supplier Concentration Risk [Member] | Accounts Payable [Member] | Two CROs [Member] |  |  |
Concentration Risk, Percentage |  | 84.80% |
Accounts Payable, Total |  | $ 1,312,000 |

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