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Note 1 - Organization and Summary of Significant Accounting Policies - Accounts Payable (Details) - USD ($)	Dec. 31, 2021	Dec. 31, 2020
Research and development expenses	$ 1,363,889	$ 904,572
Legal expenses	27,675	24,496
Other	156,389	84,031
Accounts Payable, Current, Total	$ 1,547,953	$ 1,013,099

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