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Note 1 - Organization and Summary of Significant Accounting Policies - Research and Development Costs (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Outside contracted services $ 7,607,035 $ 3,302,034
Personnel related costs 669,328 531,405
Facilities, overhead and other 116,007 34,682
Research And Development Expense, Including Related Party $ 8,392,370 $ 3,868,121