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Note 4 - Income Taxes - Component of Deferred Tax Assets (Details) - USD ($)	Dec. 31, 2021	Dec. 31, 2020
Stock option expense	$ 947,400	$ 689,600
NOL carryforward	10,509,900	7,080,600
Research and development credits	1,656,500	1,656,500
Unrealized gain from investment in Alphazyme	(72,100)	(69,800)
Other	(6,100)	7,900
Deferred tax asset, net of deferred tax liabilities	13,035,600	9,364,800
Valuation allowance	(13,035,600)	(9,364,800)
Net deferred tax asset	$ 0	$ 0

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- Definition

Represents net of liabilities before valuation allowance for deferred tax assets.

+ References

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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Amount of deferred tax liability attributable to taxable temporary differences from investments (excludes investments in subsidiaries and equity method investments).

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