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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities    
Net loss $ (5,779,660) $ (7,141,123)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 908,291 867,191
Amortization of held-to-maturity securities, net 25,217 159,481
Foreign currency exchange loss (gain), net 10,372 46,079
Changes in operating assets and liabilities:    
Interest receivable 52,138 (51,066)
Accounts receivable (890,686) (36,049)
Prepaid expenses and other current assets 273,288 179,617
Accounts payable (430,899) 1,427,809
Accrued expenses 514,778 104,546
Deferred research and development obligation 750,184 135,732
Deferred license revenue (58,823) 0
Net cash used in operating activities (4,625,800) (4,307,783)
Cash flows from investing activities    
Purchases of held-to-maturity investment securities (6,177,270) (11,283,940)
Proceeds from maturities of investment securities 4,500,000 8,000,000
Net cash used in investing activities (1,677,270) (3,283,940)
Cash flows from financing activities    
Proceeds from exercise of options 42,350 986,140
Net cash provided by financing activities 42,350 986,140
Effect of exchange rate changes on cash (11,348) (12,636)
Net decrease in cash and cash equivalents (6,272,068) (6,618,219)
Cash and cash equivalents at beginning of period 15,748,480 20,637,045
Cash and cash equivalents at end of period $ 9,476,412 $ 14,018,826