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Note 5 - Share-based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2022
Notes Tables |
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
Risk-Free interest rate |  |  | 1.40% - 3.24% |
Expected dividend yield |  |  | —% |
Expected stock price volatility |  |  | 61.30 - 61.58% |
Expected life of options (in years) |  |  | 5.50 - 6.25 |
Share-Based Payment Arrangement, Option, Activity [Table Text Block] |
|  |  |  |  |  |  |  |  |  | Weighted-Average |  |  |  |  |
|  |  |  |  |  | Weighted-Average |  |  | Remaining Contractual |  |  | Aggregate Intrinsic |
|  | Shares |  |  | Exercise Price |  |  | Term (Years) |  |  | Value |
Outstanding at December 31, 2021 |  |  | 4,774,215 |  |  | $ | 3.04 |  |  |  | 6.14 |  |  | $ | 8,413,444 |
Granted (1) |  |  | 865,825 |  |  |  | 4.43 |  |  |  |  |  |  |  |  |
Exercised |  |  | (233,943 | ) |  |  | 1.72 |  |  |  |  |  |  |  |  |
Expired |  |  | (50,000 | ) |  |  | 6.22 |  |  |  |  |  |  |  |  |
Canceled |  |  | (75,000 | ) |  |  | 4.81 |  |  |  |  |  |  |  |  |
Outstanding at September 30, 2022 |  |  | 5,281,097 |  |  | $ | 3.27 |  |  |  | 5.72 |  |  | $ | 770,536 |
Exercisable at September 30, 2022 |  |  | 3,876,280 |  |  | $ | 2.85 |  |  |  | 4.65 |  |  | $ | 766,446 |
Share-Based Payment Arrangement, Activity [Table Text Block] |
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2022 |  |  | 2021 |  |  | 2022 |  |  | 2021 |
General and administrative |  | $ | 441,279 |  |  | $ | 405,383 |  |  | $ | 1,219,827 |  |  | $ | 1,183,568 |
Research and development |  |  | 58,640 |  |  |  | 51,826 |  |  |  | 188,383 |  |  |  | 140,832 |
Total |  | $ | 499,919 |  |  | $ | 457,209 |  |  | $ | 1,408,210 |  |  | $ | 1,324,400 |

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- Definition Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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