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v3.22.2.2

Note 1 - Organization and Summary of Significant Accounting Policies (Details Textual) | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2022 USD ($) shares | Sep. 30, 2021 USD ($) shares | Sep. 30, 2022 USD ($) shares | Sep. 30, 2021 USD ($) shares | Dec. 31, 2021 USD ($)
Number of Operating Segments |  |  | 1 |  |
Revenue from Contract with Customer, Excluding Assessed Tax | $ 879,597 | $ 692,929 | $ 2,186,577 | $ 2,090,541 |
Accounts Receivable, Allowance for Credit Loss, Ending Balance | 0 |  | 0 |  | $ 0
Deferred Tax Assets, Net, Total | $ 15,700,000 |  | $ 15,700,000 |  | $ 13,000,000.0
Deferred Tax Assets, Valuation Allowance Coverage, Percent |  |  | 100.00% |  | 100.00%
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) | shares | 5,281,097 | 4,824,215 | 5,281,097 | 4,824,215 |
Customer Concentration Risk [Member] | Revenue Benchmark [Member] |  |  |  |  |
Concentration Risk, Number of Customers | 8 | 8 | 13 | 13 |
Customer Concentration Risk [Member] | Revenue Benchmark [Member] | Non-US [Member] |  |  |  |  |
Concentration Risk, Number of Customers | 4 | 5 | 6 | 7 |
Revenue from Contract with Customer, Excluding Assessed Tax | $ 133,000 | $ 478,000 | $ 509,000 | $ 1,599,000 |
Concentration Risk, Percentage | 16.00% | 69.10% | 25.60% | 76.50% |
Customer Concentration Risk [Member] | Accounts Receivable [Member] |  |  |  |  |
Concentration Risk, Number of Customers |  |  | 4 |  | 8
Customer Concentration Risk [Member] | Accounts Receivable [Member] | Non-US [Member] |  |  |  |  |
Concentration Risk, Number of Customers |  |  | 2 |  | 4
Revenue from Contract with Customer, Excluding Assessed Tax |  |  | $ 43,000 |  |
Concentration Risk, Percentage |  |  | 17.80% |  | 56.40%
Accounts Receivable, after Allowance for Credit Loss, Total |  |  |  |  | $ 157,000
Supplier Concentration Risk [Member] | Contract Research Organizations [Member] |  |  |  |  |
Concentration Risk, Number of Customers | 3 | 2 |  |  |
Concentration Risk, Number of Suppliers |  |  | 3 | 3 |
Supplier Concentration Risk [Member] | Contract Research Organizations [Member] | Two CROs [Member] |  |  |  |  |
Concentration Risk, Percentage | 99.50% | 97.20% | 97.40% | 96.90% |
Research Services Purchased | $ 1,352,000 | $ 1,982,000 | $ 4,146,000 | $ 6,621,000 |
Supplier Concentration Risk [Member] | Accounts Payable [Member] |  |  |  |  |
Concentration Risk, Number of Suppliers |  |  | 3 |  | 2
Supplier Concentration Risk [Member] | Accounts Payable [Member] | Two CROs [Member] |  |  |  |  |
Concentration Risk, Percentage |  |  | 91.90% |  | 84.80%
Accounts Payable, Total | $ 714,000 |  | $ 714,000 |  | $ 1,312,000

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