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Note 5 - Share-based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

Risk-Free interest rate			1.40% - 3.24%
Expected dividend yield			—%
Expected stock price volatility			61.30 - 61.58%
Expected life of options (in years)			5.50 - 6.25

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

										Weighted-Average
						Weighted-Average				Remaining Contractual				Aggregate Intrinsic
		Shares				Exercise Price				Term (Years)				Value
Outstanding at December 31, 2021			4,774,215			$	3.04				6.14			$	8,413,444
Granted (1)			865,825				4.43
Exercised			(233,943	)			1.72
Expired			(50,000	)			6.22
Canceled			(75,000	)			4.81
Outstanding at September 30, 2022			5,281,097			$	3.27				5.72			$	770,536
Exercisable at September 30, 2022			3,876,280			$	2.85				4.65			$	766,446

Share-Based Payment Arrangement, Activity [Table Text Block]

		Three Months Ended September 30,								Nine Months Ended September 30,
		2022				2021				2022				2021
General and administrative		$	441,279			$	405,383			$	1,219,827			$	1,183,568
Research and development			58,640				51,826				188,383				140,832
Total		$	499,919			$	457,209			$	1,408,210			$	1,324,400

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- Definition

Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value.

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