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Note 1 - Organization and Summary of Significant Accounting Policies - Research and Development Costs (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Outside contracted services $ 550,750 $ 1,700,280 $ 3,302,911 $ 5,396,227
Personnel related costs 186,993 174,856 593,258 472,605
Facilities, overhead and other 5,842 26,412 21,076 50,056
Research And Development Expense, Including Related Party $ 743,585 $ 1,901,548 $ 3,917,245 $ 5,918,888