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Consolidated Statements of Cash Flows (Unaudited) - USD ($)	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities
Net loss	$ (7,588,833)	$ (8,856,391)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	1,408,210	1,324,400
Amortization of held-to-maturity securities, net	37,094	254,193
Gain on investment in BDI	0	(1,605,532)
Foreign currency exchange loss (gain), net	23,579	76,081
Changes in operating assets and liabilities:
Interest receivable	50,502	37,454
Accounts receivable	(14,837)	72,051
Prepaid expenses and other current assets	(70,051)	(289,481)
Accounts payable	(716,964)	(47,033)
Accrued expenses	278,331	352,713
Deferred research and development obligation	293,897	39,664
Deferred license revenue	(102,941)	0
Net cash used in operating activities	(6,402,013)	(8,641,881)
Cash flows from investing activities
Purchases of held-to-maturity investment securities	(8,487,198)	(11,283,940)
Proceeds from maturities of investment securities	5,500,000	10,400,000
Proceeds from the sale of investment in BDI	0	1,605,532
Net cash (used in) provided by investing activities	(2,987,198)	721,592
Cash flows from financing activities
Proceeds from exercise of options	402,091	985,550
Net cash provided by financing activities	402,091	985,550
Effect of exchange rate changes on cash	(22,243)	(41,695)
Net decrease in cash and cash equivalents	(9,009,363)	(6,976,434)
Cash and cash equivalents at beginning of period	15,748,480	20,637,045
Cash and cash equivalents at end of period	$ 6,739,117	$ 13,660,611

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