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Note 6 - Share-based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2022
Notes Tables |
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
|  | Years Ended December 31, |
|  | 2022 |  |  | 2021 |
Risk-free interest rate |  |  | 1.40% - 3.24% |  |  |  | 0.05% - 1.24% |
Expected dividend yield |  |  | —% |  |  |  | —% |
Expected stock price volatility |  |  | 61.30% - 61.58% |  |  |  | 54.52% - 60.80% |
Expected life of options (in years) |  |  | 5.5 - 6.25 |  |  |  | 0.5 - 6.25 |
Share-Based Payment Arrangement, Option, Activity [Table Text Block] |
|  |  |  |  |  |  |  |  |  | Weighted- |  |  |  |  |
|  |  |  |  |  |  |  |  |  | Average |  |  |  |  |
|  |  |  |  |  | Weighted- |  |  | Remaining |  |  | Aggregate |
|  |  |  |  |  | Average |  |  | Contractual |  |  | Intrinsic |
|  | Shares |  |  | Exercise Price |  |  | Term (Years) |  |  | Value |
Outstanding at December 31, 2020 |  |  | 4,638,390 |  |  | $ | 2.44 |  |  |  | 5.64 |  |  | $ | 13,701,610 |
Granted |  |  | 870,825 |  |  |  | 5.11 |  |  |  |  |  |  |  |  |
Exercised |  |  | (735,000 | ) |  |  | 1.67 |  |  |  |  |  |  |  |  |
Expired |  |  | — |  |  |  | — |  |  |  |  |  |  |  |  |
Canceled |  |  | — |  |  |  | — |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2021 |  |  | 4,774,215 |  |  | $ | 3.04 |  |  |  | 6.14. |  |  | $ | 8,413,444 |
Granted (1) |  |  | 865,825 |  |  |  | 4.43 |  |  |  |  |  |  |  |  |
Exercised (2) |  |  | (333,943 | ) |  |  | 1.63 |  |  |  |  |  |  |  |  |
Expired (3) |  |  | (200,000 | ) |  |  | 5.47 |  |  |  |  |  |  |  |  |
Canceled (4) |  |  | (75,000 | ) |  |  | 4.81 |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2022 |  |  | 5,031,097 |  |  | $ | 3.25 |  |  |  | 5.75 |  |  | $ | 13,000 |
Exercisable at December 31, 2022 |  |  | 3,655,280 |  |  | $ | 2.80 |  |  |  | 4.75 |  |  | $ | 13,000 |
Share-Based Payment Arrangement, Activity [Table Text Block] |
|  | Years Ended December 31, |
|  | 2022 |  |  | 2021 |
General and administrative |  | $ | 1,661,025 |  |  | $ | 1,571,328 |
Research and development |  |  | 227,919 |  |  |  | 212,774 |
Total |  | $ | 1,888,944 |  |  | $ | 1,784,102 |

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- Definition Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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