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v3.23.1

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Cash flows from operating activities |  |
Net loss | $ (9,735,258) | $ (13,070,251)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 1,888,944 | 1,784,102
Amortization of held-to-maturity securities, net | 33,790 | 329,612
Gain on investment in BDI | 0 | (1,605,532)
Foreign currency exchange loss | 49,918 | 96,893
Changes in operating assets and liabilities: |  |
Interest receivable | 36,090 | 17,872
Accounts receivable | (83,265) | (31,792)
Prepaid expenses and other current assets | (13,925) | (95,366)
Accounts payable | (248,128) | 549,562
Accrued expenses | 245,521 | 219,824
Deferred license revenue | (147,058) | 500,000
Deferred research and development obligations | (110,404) | 28,131
Net cash used in operating activities | (8,083,775) | (11,276,945)
Cash flows from investing activities |  |
Purchases of held-to-maturity investment securities | (9,869,280) | (11,283,940)
Proceeds from maturities of investment securities | 7,500,000 | 14,900,000
Proceeds from the sale of investment in BDI | 0 | 1,605,532
Net cash (used in) provided by investing activities | (2,369,280) | 5,221,592
Cash flows from financing activities |  |
Proceeds from exercise of options | 543,591 | 1,230,050
Net cash provided by financing activities | 543,591 | 1,230,050
Effect of exchange rate changes on cash | (44,744) | (63,262)
Net decrease in cash and cash equivalents | (9,954,208) | (4,888,565)
Cash and cash equivalents at beginning of period | 15,748,480 | 20,637,045
Cash and cash equivalents at end of period | $ 5,794,272 | $ 15,748,480

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