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Note 6 - Share-based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Years Ended December 31,
		2022				2021
Risk-free interest rate			1.40% - 3.24%				0.05% - 1.24%
Expected dividend yield			—%				—%
Expected stock price volatility			61.30% - 61.58%				54.52% - 60.80%
Expected life of options (in years)			5.5 - 6.25				0.5 - 6.25

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

										Weighted-
										Average
						Weighted-				Remaining				Aggregate
						Average				Contractual				Intrinsic
		Shares				Exercise Price				Term (Years)				Value
Outstanding at December 31, 2020			4,638,390			$	2.44				5.64			$	13,701,610
Granted			870,825				5.11
Exercised			(735,000	)			1.67
Expired			—				—
Canceled			—				—
Outstanding at December 31, 2021			4,774,215			$	3.04				6.14.			$	8,413,444
Granted (1)			865,825				4.43
Exercised (2)			(333,943	)			1.63
Expired (3)			(200,000	)			5.47
Canceled (4)			(75,000	)			4.81
Outstanding at December 31, 2022			5,031,097			$	3.25				5.75			$	13,000
Exercisable at December 31, 2022			3,655,280			$	2.80				4.75			$	13,000

Share-Based Payment Arrangement, Activity [Table Text Block]

		Years Ended December 31,
		2022				2021
General and administrative		$	1,661,025			$	1,571,328
Research and development			227,919				212,774
Total		$	1,888,944			$	1,784,102

X

- Definition

Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value.

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