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Note 5 - Share-based Compensation - Noncash Stock Option Compensation (Details) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Stock-based compensation | $ 281,307 | $ 499,919 | $ 946,262 | $ 1,408,210
Share-Based Payment Arrangement, Option [Member] |  |  |  |
Stock-based compensation | 224,749 | 499,919 | 779,663 | 1,408,210
Restricted Stock Units (RSUs) [Member] |  |  |  |
Stock-based compensation | 56,558 | 0 | 166,599 | 0
General and Administrative Expense [Member] |  |  |  |
Stock-based compensation | 270,672 | 441,279 | 913,804 | 1,219,827
Research and Development Expense [Member] |  |  |  |
Stock-based compensation | $ 10,635 | $ 58,640 | $ 32,458 | $ 188,383

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479830/718-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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