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Note 5 - Share-based Compensation (Tables)
9 Months Ended
Sep. 30, 2023
Notes Tables  
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

Risk-Free interest rate

  3.90% - 5.12% 

Expected dividend yield

  

—%

 

Expected stock price volatility

  

62.22% - 64.27%

 

Expected life of options (in years)

  1.13 - 6.25 
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
          

Weighted-Average

     
      

Weighted-Average

  

Remaining Contractual

  

Aggregate Intrinsic

 
  

Shares

  

Exercise Price

  

Term (Years)

  

Value

 

Outstanding at December 31, 2022

  5,031,097  $3.25   5.75  $13,000 

Granted (1)

  800,350   1.45         

Exercised

              

Expired (2)

  (320,000)  1.62         

Canceled(3)

  (15,680)  3.50         

Outstanding at September 30, 2023

  5,495,767  $3.08   5.80  $987,330 
                 

Exercisable at September 30, 2023

  4,191,818  $3.15   5.03  $559,251 
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
      

Weighted-Average

 
      

Grant Date

 
  

Shares

  

Fair Value

 

Outstanding at December 31, 2022

    $ 

Granted (1)

  411,005   1.38 

Vested (1)

  (247,961)  1.38 

Outstanding at September 30, 2023

  163,044  $1.38 
Share-Based Payment Arrangement, Activity [Table Text Block]
  

Three Months Ended September 30,

  

Nine Months Ended September 30,

 
  

2023

  

2022

  

2023

  

2022

 

General and administrative

 $270,672  $441,279  $913,804  $1,219,827 

Research and development

  10,635   58,640   32,458   188,383 

Total

 $281,307  $499,919  $946,262  $1,408,210 
  

Three Months Ended September 30,

  

Nine Months Ended September 30,

 
  

2023

  

2022

  

2023

  

2022

 

Share based compensation expense- stock option

 $224,749  $499,919  $779,663  $1,408,210 

Share based compensation expense- restricted stock units

  56,558      166,599    

Total

 $281,307  $499,919  $946,262  $1,408,210