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Note 1 - Organization and Summary of Significant Accounting Policies - Research and Development Costs (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Outside contracted services $ 2,677,941 $ 3,707,269
Personnel related costs 553,741 743,051
Facilities, overhead and other 65,584 51,045
Research And Development Expense, Including Related Party $ 3,297,266 $ 4,501,365