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Note 6 - Share-based Compensation - Noncash Stock Option Compensation (Details) - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Stock-based compensation | $ 297,603 | $ 334,316 | $ 604,081 | $ 664,955
Share based compensation expense - stock option | 297,603 | 334,316 | 604,081 | 664,955
Share-Based Payment Arrangement, Option [Member] |  |  |  |
Stock-based compensation | 243,538 | 278,373 | 433,807 | 554,914
Share based compensation expense - stock option | 243,538 | 278,373 | 433,807 | 554,914
Restricted Stock Units (RSUs) [Member] |  |  |  |
Stock-based compensation | 54,065 | 55,943 | 170,274 | 110,041
Share based compensation expense - stock option | 54,065 | 55,943 | 170,274 | 110,041
General and Administrative Expense [Member] |  |  |  |
Stock-based compensation | 285,372 | 323,796 | 579,406 | 643,132
Share based compensation expense - stock option | 285,372 | 323,796 | 579,406 | 643,132
Research and Development Expense [Member] |  |  |  |
Stock-based compensation | 12,231 | 10,520 | 24,675 | 21,823
Share based compensation expense - stock option | $ 12,231 | $ 10,520 | $ 24,675 | $ 21,823

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479830/718-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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