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Note 6 - Share-based Compensation (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Years Ended December 31,
		2024				2023
Risk-free interest rate			3.56% - 4.61	%			3.90% -5.12	%
Expected dividend yield			—	%			—	%
Expected stock price volatility			63.02-63.64	%			62.22% - 64.27	%
Expected life of options (in years)			2.63-6.25				1.13 -6.25

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

										Weighted-
										Average
						Weighted-				Remaining				Aggregate
						Average				Contractual				Intrinsic
		Shares				Exercise Price				Term (Years)				Value
Outstanding at December 31, 2022			5,031,097			$	3.25				5.75			$	13,000
Granted			805,350				1.45
Exercised			—				—
Expired			(351,520	)			1.71
Canceled			(15,680	)			3.50
Outstanding at December 31, 2023			5,469,247			$	3.08				5.66			$	322,738
Granted (1)			830,725				1.61
Exercised (2)			(55,000	)			1.18
Expired (3)			(383,063	)			2.16
Canceled (4)			(73,312	)			1.73
Outstanding at December 31, 2024			5,788,597			$	2.97				5.34			$	655,578
Exercisable at December 31, 2024			4,438,810			$	3.19				4.44			$	436,263

Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]

						Weighted-Average
						Grant Date
		Shares				Fair Value
Outstanding at December 31, 2023			213,044				1.43
Granted (1)			354,219				1.60
Vested (2)			(437,546	)			1.52
Unvested shares forfeited (3)			(11,792	)			1.59
Outstanding at December 31, 2024			117,925			$	1.59

Share-Based Payment Arrangement, Activity [Table Text Block]

		Years Ended December 31,
		2024				2023
General and administrative		$	1,067,750			$	1,201,027
Research and development			58,529				43,094
Total		$	1,126,279			$	1,244,121

		Years Ended December 31,
		2024				2023
Share-based compensation expenses- stock option		$	861,999			$	1,004,054
Share-based compensation expenses- restricted stock units			264,280				240,067
Total		$	1,126,279			$	1,244,121

X

- Definition

Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value.

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