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Note 6 - Share-based Compensation - Noncash Stock Option Compensation (Details) - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Stock-based compensation	$ 1,126,279	$ 1,244,121
Share-based compensation expenses	1,126,279	1,244,121
Share-Based Payment Arrangement, Option [Member]
Stock-based compensation	861,999	1,004,054
Share-based compensation expenses	861,999	1,004,054
Restricted Stock Units (RSUs) [Member]
Stock-based compensation	264,280	240,067
Share-based compensation expenses	264,280	240,067
General and Administrative Expense [Member]
Stock-based compensation	(1,067,750)	(1,201,027)
Share-based compensation expenses	(1,067,750)	(1,201,027)
Research and Development Expense [Member]
Stock-based compensation	58,529	43,094
Share-based compensation expenses	$ 58,529	$ 43,094

X

- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 718
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 14.F)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479830/718-10-S99-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 718
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480429/718-10-50-2

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